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Find Resorts & Hotels with Spas in Northeast Missouri, MO

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Check availability on Northeast Missouri Resorts & Hotels with Spas

Tonight
Oct 22 - Oct 23
Tomorrow
Oct 23 - Oct 24
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Our top choices for Northeast Missouri hotels with a spa

A wooden interior with a hot tub, a wheelchair-accessible bench, and a window.
A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.
A hotel room with a bed, a sofa, a desk, and a lamp.
A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.

1. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
Hannibal
  • Serene spa sanctuary awaits in the heart of Hannibal with rejuvenating hot tub, indoor pool, and hydromassage showers.
NT$2,544
NT$3,031 total
includes taxes & fees
Nov 15 - Nov 16
Comfort Inn & Suites - Hannibal
A modern reception area with a marble counter, a wooden panel with a light fixture, a fireplace, and a seating area with a sofa and chairs.
A hotel room with a sofa, armchair, lamp, and a large mirror.
A Holiday Inn hotel with a modern facade, a covered entrance, and landscaped areas with shrubs.
A spacious lobby with a fireplace, seating area, and large windows.

2. Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
Quincy
  • Revitalizing spa treatments await at this hotel, where an indoor pool, cozy pillow menus, and attentive staff create a relaxing retreat.
NT$3,599
NT$4,103 total
includes taxes & fees
Nov 22 - Nov 23
Holiday Inn Quincy East by IHG
A bathroom with a white sink, dark wooden door, and a shower area with striped glass walls.
A room with a green armchair, a round table, a lamp, and a mirror on the wall.
A modern interior with a staircase, a large abstract painting, and a seating area with a glass coffee table.
A room with a bed, a nightstand with a lamp, a painting on the wall, and a radiator.

3. Truitt Hotel

Truitt Hotel
Lafayette Square
NT$5,448
NT$6,613 total
includes taxes & fees
Oct 25 - Oct 26
Truitt Hotel
A modern spa with a curved reception desk, a large mirror, and a decorative water feature.
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A bar area with multiple seating arrangements, a stage, and a chandelier.
A bakery display case with various pastries and cakes.

4. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
NT$5,162
NT$6,571 total
includes taxes & fees
Nov 16 - Nov 17
Ameristar Casino Resort and Spa
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.

5. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
NT$4,658
NT$5,609 total
includes taxes & fees
Nov 22 - Nov 23
21C Museum Hotel St Louis
A spa area with a massage table, a hot tub, and a grill.
A row of houses with a driveway leading to a gated entrance.
A hot tub, a fire pit, and a view of a lake.
A hot tub with a view of a forest, a bath brush, and a robe hanging on the wall.

6. Hermann Hill

Hermann Hill
Hermann
  • Riverside bed and breakfast with private hot tubs and spa treatments offers romantic rejuvenation.
NT$9,874
NT$11,353 total
includes taxes & fees
Nov 17 - Nov 18
Hermann Hill
A modern kitchen with wooden cabinets, a central island, and framed artwork on the walls.
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.
A bar area with leather seating, a bar counter, and shelves of bottles.
A couple standing on a balcony with a cityscape view.

7. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
NT$18,897
NT$22,060 total
includes taxes & fees
Nov 1 - Nov 2
The Ritz-Carlton, St. Louis
A couple relaxing by a window overlooking a bridge and water.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.
A modern hotel lobby with a glass facade, seating area, and a staircase.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.

8. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
NT$12,160
NT$14,219 total
includes taxes & fees
Oct 25 - Oct 26
Four Seasons Hotel St Louis
View all properties

Choose what matters most at spa hotels in Northeast Missouri

Pool
Breakfast included
Hot tub
4 stars
5 stars

Spa hotels with free breakfast in Northeast Missouri

A hotel room with a bed, a sofa, a desk, and a lamp.
A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.
An indoor swimming pool with wooden walls, a tiled floor, and a sign indicating no diving is allowed.
A restaurant with multiple tables and chairs, an exit sign, and a counter area.

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
Hannibal
NT$2,544
NT$3,031 total
includes taxes & fees
Nov 15 - Nov 16
Comfort Inn & Suites - Hannibal
A modern reception area with a marble counter, a wooden panel with a light fixture, a fireplace, and a seating area with a sofa and chairs.
A hotel room with a sofa, armchair, lamp, and a large mirror.
A Holiday Inn hotel with a modern facade, a covered entrance, and landscaped areas with shrubs.
A spacious lobby with a fireplace, seating area, and large windows.

Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
Quincy
NT$3,599
NT$4,103 total
includes taxes & fees
Nov 22 - Nov 23
Holiday Inn Quincy East by IHG
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."
A spacious lobby with multiple seating areas, a pool table, and artwork on the walls.
A reception desk with a wooden finish and the name "IDOL WOLF" on it.

21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
NT$4,658
NT$5,609 total
includes taxes & fees
Nov 22 - Nov 23
21C Museum Hotel St Louis
A hot tub, a fire pit, and a view of a lake.
A hotel room with a large bed, a bathtub, and a view of the outdoors.
A hot tub with a view of a forest, a bath brush, and a robe hanging on the wall.
A row of houses with a driveway leading to a gated entrance.

Hermann Hill

Hermann Hill
Hermann
NT$9,874
NT$11,353 total
includes taxes & fees
Nov 17 - Nov 18
Hermann Hill
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.
A bar area with leather seating, a bar counter, and shelves of bottles.
A lobby with a fireplace, two armchairs, a round table, and a bench.
A modern living room with a sofa, chairs, a coffee table, and a chandelier.

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
NT$18,897
NT$22,060 total
includes taxes & fees
Nov 1 - Nov 2
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Northeast Missouri Hotel Reviews

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent
"Loved the area to the event"
Jorge 3-night trip
Posted 4 hours ago
Pear Tree Inn St. Louis Near Union Station
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

10/10 Excellent
"Room was quite large and very comfortable."
Barbara 3-night trip
Posted 13 hours ago
Ameristar Casino Resort and Spa
Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"The staff were friendly and helpful. It was a wonderful stay a around"
Irma 1-night trip
Posted 1 day ago
Drury Plaza Hotel St. Louis Union Station

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