Find Luxury Hotels in Northeast Missouri, MO
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Northeast Missouri Luxury Hotels
Our top choices for Northeast Missouri luxury hotels
The Royal Sonesta Chase Park Plaza St. Louis
The Royal Sonesta Chase Park Plaza St. LouisCentral West End
9.0 out of 10, Wonderful, (1003)
"Clean nice room, friendly staff, and good restaurants "
Timothy
The price is NT$4,739
NT$6,513 total
includes taxes & fees
Jan 18 - 2026/1/19
8.4 out of 10, Very Good, (1001)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
Robyn
The price is NT$5,620
NT$7,090 total
includes taxes & fees
Jan 12 - 2026/1/13
9.2 out of 10, Wonderful, (554)
"The stay was ok even though nothing was explained to be. The hours of restaurant, where the gym is located about the bar in the room nothing. "
Shemelle
The price is NT$15,659
NT$18,280 total
includes taxes & fees
Jan 2 - 2026/1/3
5.0 out of 10, (172)
"We did not stay there the motel was condemed The website needs to be took down"
Anonymous traveler
7.0 out of 10, Good, (1000)
"The room was comfortable and clean."
Lady Gina
The price is NT$2,135
NT$2,434 total
includes taxes & fees
Jan 20 - 2026/1/21
8.8 out of 10, Excellent, (3044)
"Great stay‼️"
Calvin
The price is NT$2,958
NT$3,454 total
includes taxes & fees
Jan 30 - 2026/1/31
8.6 out of 10, Excellent, (1004)
"Great location "
Gregory
The price is NT$4,511
NT$5,275 total
includes taxes & fees
Jan 15 - 2026/1/16
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Magnolia Hotel St. Louis, a Tribute Portfolio HotelDowntown St. Louis
8.8 out of 10, Excellent, (1178)
"Great staff and location"
Robin or David
The price is NT$3,046
NT$3,623 total
includes taxes & fees
Jan 25 - 2026/1/26
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Northeast Missouri Hotel Reviews
Pear Tree Inn St. Louis Airport
10/10 Excellent
Explore a world of travel with Expedia
- Memphis Hotels
- Marriott Hotels & Resorts in Hannibal
- Kirksville Hotels
- Romantic Hotels in Hannibal
- Golf Hotels in Canton
- Hotels near Jim's Journey: The Huck Finn Freedom Center
- Hotels near Molly Brown Museum and Home
- Golf Hotels in Moberly
- Stoutsville Hotels
- Perry Hotels
- B&B in Memphis
- Moberly Hotels
- Hotels with smoking rooms in Hannibal
- Hotels near Mark Twain Casino
- Pet-Friendly Hotels in Hannibal
- Hotels near Truman State University
- 4 Star Hotels in Hannibal
- Hannibal Hotels
- Hotel with a Concierge Hotels in Macon
- Pet-Friendly Hotels in Brookfield
- Hotels with Hot Tubs in Macon
- Hotels with a Pool in Brookfield
- Resorts & Hotels with Spas in Perry
- Pet-Friendly Hotels in Monroe City
- Historic Hotels in Mexico
- Hotels near Rockcliffe Mansion
- Pet-Friendly Hotels in Mexico
- Macon Hotels
- Luxury Hotels in Rutledge
- Hotels with Bars in Rutledge
- Kahoka Hotels
- Hotels with an Indoor Pool in Macon
- Shelbina Hotels
- Golf Hotels in Hannibal
- Hotels near Heritage Hills Golf Course
- Palmyra Hotels
- Cheap Hotels in New Cambria
- Hotels with Bars in Hannibal
- Hotels near Magic City Line Mini Train
- Flights from St. Petersburg (PIE) to Kirksville (IRK)
- Flights from Waukesha (UES) to Kirksville (IRK)
- Flights from Dothan (DHN) to Kirksville (IRK)
- Flights from Tupelo (TUP) to Kirksville (IRK)
- Flights from Chennai (MAA) to Kirksville (IRK)
- Flights from Takapoto (TKP) to Kirksville (IRK)
- Flights to Memphis
- Flights from Hanoi (HAN) to Kirksville (IRK)
- Flights from Flint (FNT) to Kirksville (IRK)
- Flights from Appleton (ATW) to Kirksville (IRK)
- Flights from Rutledge
- Flights from Chattanooga (CHA) to Kirksville (IRK)
- Flights from Kirksville Municipal
- Flights to Ethel
- Flights from Old Crow (YOC) to Kirksville (IRK)
- Flights from Carbondale (MDH) to Kirksville (IRK)
- Flights from Novinger
- Flights from Hannibal
- Flights from Jacobabad (JAG) to Kirksville (IRK)
- Flights to Palmyra
- Flights from Burbank (BUR) to Kirksville (IRK)
- Flights to Shelbina
- Flights from Shelbina
- Flights from Maywood
- Flights from Puebla (PBC) to Kirksville (IRK)
- Flights from Akron (CAK) to Kirksville (IRK)
- Flights from Cape Girardeau (CGI) to Kirksville (IRK)
- Flights from Neuquén (NQN) to Kirksville (IRK)
- Flights from Memphis
- Flights to Hannibal
- Flights from San Diego (SAN) to Kirksville (IRK)
- Visit Lentner
- Visit Gibbs
- Visit Stoutsville
- Visit Hannibal
- Visit Novinger
- Visit Holliday
- Mark Twain Memorial Lighthouse
- Visit Shelbina
- Visit La Plata
- Jim's Journey: The Huck Finn Freedom Center
- Magic City Line Mini Train
- Visit Callao
- Hannibal Vacations
- Truman State University
- Visit La Grange
- Kahoka Vacations
- Mark Twain Casino
- Memphis Vacations
- Visit New London
- Car rental Hannibal
- Budget Rental Cars in Taylor
- Thrifty Car Rental Rental Cars in Palmyra
- Thrifty Car Rental Rental Cars in Kirksville Municipal
- Car rental Kahoka
- Car rental Monroe City
- First-Car Rental Cars in Taylor
- Top Rent a Car Rental Cars in Edina
- Rental cars Kirksville Municipal airport
- Budget Rental Cars in Holliday
- Dollar Rent A Car Rental Cars in Granger