Find hotels in Mayo Clinic, Phoenix

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mayo Clinic hotels

Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus
3.0 star property
Mayo Clinic
8.2 out of 10, Very Good, (1,075 reviews)
"Beautiful room, couteous and experienced front desk staff. Easiest check in."
United States
April
The price is NT$4,145
NT$4,724 total
includes taxes & fees
Jan 20 - Jan 21
Sonesta Select Scottsdale at Mayo Clinic Campus

Stay7 Studios Hotel Phoenix

Stay7 Studios Hotel Phoenix
2.0 star property
29.8 km from Mayo Clinic
7.4 out of 10, Good, (81 reviews)
"Very pleasant stay."
United States
Michelle
The price is NT$2,134
NT$2,413 total
includes taxes & fees
Jan 20 - Jan 21
Stay7 Studios Hotel Phoenix

Hilton Garden Inn Phoenix Airport North

Hilton Garden Inn Phoenix Airport North
3.0 star property
24.2 km from Mayo Clinic
8.6 out of 10, Excellent, (2,407 reviews)
"Great value and close to wherever we needed to go"
United States
Gabriel
The price is NT$3,735
NT$4,223 total
includes taxes & fees
Jan 23 - Jan 24
Hilton Garden Inn Phoenix Airport North

La Quinta Inn & Suites by Wyndham Mesa Superstition Springs

La Quinta Inn & Suites by Wyndham Mesa Superstition Springs
3.0 star property
24.1 km from Mayo Clinic
8.2 out of 10, Very Good, (1,825 reviews)
"Clean rooms and friendly staff. "
United States
Maria
The price is NT$3,274
NT$3,741 total
includes taxes & fees
Jan 25 - Jan 26
La Quinta Inn & Suites by Wyndham Mesa Superstition Springs

Scottsdale Parkview Resort

Scottsdale Parkview Resort
3.5 star property
17.6 km from Mayo Clinic
8.0 out of 10, Very Good, (5,214 reviews)
"Great stay, friendly staff and excellent location!"
United States
Michael Jason
The price is NT$2,929
NT$3,572 total
includes taxes & fees
Jan 19 - Jan 20
Scottsdale Parkview Resort

Days Inn & Suites by Wyndham Mesa Near Phoenix

Days Inn & Suites by Wyndham Mesa Near Phoenix
3.0 star property
23 km from Mayo Clinic
9.0 out of 10, Wonderful, (2,117 reviews)
"Very quiet, clean, good breakfast and very courteous staff all the way around! "
United States
Candace
The price is NT$2,630
NT$3,006 total
includes taxes & fees
Jan 25 - Jan 26
Days Inn & Suites by Wyndham Mesa Near Phoenix

Drury Inn & Suites Phoenix Airport

Drury Inn & Suites Phoenix Airport
3.0 star property
27.7 km from Mayo Clinic
9.6 out of 10, Exceptional, (2,354 reviews)
"It was a great stay!"
United States
Nicholas
The price is NT$4,078
NT$4,610 total
includes taxes & fees
Jan 25 - Jan 26
Drury Inn & Suites Phoenix Airport

SureStay Hotel by Best Western Phoenix Airport

SureStay Hotel by Best Western Phoenix Airport
2.5 star property
25.5 km from Mayo Clinic
8.4 out of 10, Very Good, (1,581 reviews)
"Clean and comfortable rooms l, will stay again "
United States
Bhargab
The price is NT$2,497
NT$2,824 total
includes taxes & fees
Feb 3 - Feb 4
SureStay Hotel by Best Western Phoenix Airport

The Azure Hotel

The Azure Hotel
2.5 star property
19.2 km from Mayo Clinic
8.8 out of 10, Excellent, (1,633 reviews)
"Rooms were clean, beds were comfy and the hotel was generally quiet. "
United States
Aaron
The Azure Hotel

Hyatt Place Phoenix/Mesa

Hyatt Place Phoenix/Mesa
3.0 star property
17.9 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,718 reviews)
"Good breakfast and staff very helpful."
United States
Neal
The price is NT$4,268
NT$4,877 total
includes taxes & fees
Jan 25 - Jan 26
Hyatt Place Phoenix/Mesa

Holiday Inn Express & Suites Phoenix - Airport North by IHG

Holiday Inn Express & Suites Phoenix - Airport North by IHG
2.5 star property
23.2 km from Mayo Clinic
9.4 out of 10, Exceptional, (2,164 reviews)
"It was a good overall stay. "
United States
Vincent
The price is NT$4,236
NT$4,790 total
includes taxes & fees
Jan 25 - Jan 26
Holiday Inn Express & Suites Phoenix - Airport North by IHG

Inn at Eagle Mountain

Inn at Eagle Mountain
3.5 star property
3 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,003 reviews)
"Great place to stay. "
United States
Alexandra
The price is NT$6,167
NT$7,041 total
includes taxes & fees
Jan 18 - Jan 19
Inn at Eagle Mountain

Papago Scottsdale by Reside, Trademark Collection by Wyndham

Papago Scottsdale by Reside, Trademark Collection by Wyndham
3.0 star property
18.5 km from Mayo Clinic
8.6 out of 10, Excellent, (298 reviews)
"Room was clean and service was great."
United States
Zoar
The price is NT$3,386
NT$3,859 total
includes taxes & fees
Jan 25 - Jan 26
Papago Scottsdale by Reside, Trademark Collection by Wyndham

SureStay Plus by Best Western Mesa Superstition Springs

SureStay Plus by Best Western Mesa Superstition Springs
2.5 star property
23.4 km from Mayo Clinic
8.4 out of 10, Very Good, (1,690 reviews)
"Room was clean and staff very pleasant. "
United States
Jovana
The price is NT$3,762
NT$4,299 total
includes taxes & fees
Jan 19 - Jan 20
SureStay Plus by Best Western Mesa Superstition Springs

Sentral Sol Modern

Sentral Sol Modern
4.0 star property
29.9 km from Mayo Clinic
9.6 out of 10, Exceptional, (146 reviews)
"Friendly staff, clean room, great place and easy parking ."
United States
Steve
The price is NT$4,541
NT$5,925 total
includes taxes & fees
Jan 26 - Jan 27
Sentral Sol Modern

Home2 Suites by Hilton Phoenix Downtown

Home2 Suites by Hilton Phoenix Downtown
3.0 star property
30.3 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,214 reviews)
"Nice locations"
United States
Milena
The price is NT$4,172
NT$4,717 total
includes taxes & fees
Jan 24 - Jan 25
Home2 Suites by Hilton Phoenix Downtown

Hotel San Carlos - Downtown Convention Center

Hotel San Carlos - Downtown Convention Center
3.0 star property
30.1 km from Mayo Clinic
7.6 out of 10, Good, (1,003 reviews)
"Great stay "
United States
David
The price is NT$8,820
NT$10,289 total
includes taxes & fees
Jan 16 - Jan 17
Hotel San Carlos - Downtown Convention Center

Wekopa Casino Resort

Wekopa Casino Resort
4.0 star property
10.1 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,000 reviews)
"One of the best places I have ever stayed at. Very clean and the staff was superb."
United States
Thomas
Wekopa Casino Resort

Radisson Hotel Phoenix Airport

Radisson Hotel Phoenix Airport
3.5 star property
23.3 km from Mayo Clinic
8.6 out of 10, Excellent, (1,864 reviews)
"Great service and breakfast "
United States
Ellason
The price is NT$3,735
NT$4,223 total
includes taxes & fees
Jan 25 - Jan 26
Radisson Hotel Phoenix Airport

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
3.0 star property
Central Scottsdale, 9 km from Mayo Clinic
8.8 out of 10, Excellent, (1,841 reviews)
"Fantastic room, staff and breakfast!"
United States
Terry G
The price is NT$4,475
NT$5,100 total
includes taxes & fees
Jan 28 - Jan 29
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mayo Clinic

Find the best Mayo Clinic areas and neighborhoods for the activities you enjoy most.

Downtown Phoenix

A true urban neighborhood, Downtown Phoenix boasts major sports venues like Chase Field and Footprint Center, as well as cultural attractions such as the Arizona Science Center and Phoenix Art Museum. Easily accessible via Valley Metro Light Rail, enjoy walkable streets, friendly cafes, and local businesses.

Old Town

Old Town is known for its popular shops, and you can see some sights in the area like Western Spirit: Scottsdale's Museum of the West and Scottsdale Fashion Square.

Camelback East

Adjacent to Paradise Valley and Scottsdale, Camelback East Village boasts two main cores and sits between Piestewa Peak and Camelback Mountain. Explore the vibrant 24th Street and Camelback Road or 44th Street and Van Buren Street areas.

North Phoenix

While you're in North Phoenix, take in top sights like Reach 11 Sports Complex and jump on the metro at 19th Avenue/ Dunlap Station to see more of the city.

East Mesa

While you're in East Mesa, take in top sights like Salt River Tubing and jump on the metro at Superstition Springs Transit Center to see more of the city.

Top Mayo Clinic Hotel Reviews

Frequently asked questions

What is Mayo Clinic like?
Travelers will be sure to find plenty to entertain them in Scottsdale's Mayo Clinic neighborhood.
Where is the best place to stay in Mayo Clinic?
Based on Expedia customer reviews, Sonesta Select Scottsdale at Mayo Clinic Campus is the highest ranked property in Mayo Clinic. This hotel is a short 4-minute walk from Mayo Clinic Scottsdale, and it offers a restaurant and an outdoor pool.
How many hotels will I be able to find in the Mayo Clinic area?
With 14 Expedia hotels and other accommodations in Mayo Clinic to choose from, this is a good starting point for exploring the greater Scottsdale area.
If I need to cancel my hotel reservation in Mayo Clinic, will I receive a refund?
Yes! Most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in Mayo Clinic.
Where can I learn more about changing or cancelling my trip to Mayo Clinic?
For more information about updating your trip to Mayo Clinic or cancelling it, go to https://www.expedia.com/service/.
What is there to do around this Scottsdale neighborhood?
A few places to visit in the area around Mayo Clinic include Eagle Mountain Golf Course, Golf Club at Eagle Mountain, and SunRidge Canyon Golf Club. Make a stop at Talking Stick Resort Casino and OdySea Aquarium while you're sightseeing around the area.

Explore a world of travel with Expedia