Find Family Hotels in Lake City, SC

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Lake City Family Hotels

Our top choices for Lake City family-friendly hotels

Lobby
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
7.8 out of 10, Good, (1256)
"Room was spotless, bed extremely comfortable and staff was very helpful and courteous. Would DEFINITELY stay there again. "
United States
Tim
The price is NT$2,437
NT$2,729 total
includes taxes & fees
Jan 15 - 2026/1/16
Quality Inn & Suites Florence Civic Center
Desk, iron/ironing board, free WiFi, bed sheets
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center
2.5 star property
Florence
6.8 out of 10, (1003)
"Clean rooms and wonderful staff "
United States
Rita
The price is NT$1,934
NT$2,166 total
includes taxes & fees
Dec 17 - Dec 18
Days Inn by Wyndham Florence Near Civic Center
Exterior
Aloft Florence

Aloft Florence

Aloft Florence
3.0 star property
Florence
8.6 out of 10, Excellent, (249)
"You have to try the apple muffin. It’s so delicious my whole family had to try it. "
United States
Tyler
The price is NT$3,151
NT$3,529 total
includes taxes & fees
Dec 21 - Dec 22
Aloft Florence
Desk, laptop workspace, free cribs/infant beds, free WiFi
Red Roof Inn Florence - Civic Center

Red Roof Inn Florence - Civic Center

Red Roof Inn Florence - Civic Center
2.0 star property
Florence
6.8 out of 10, (1001)
"Small Budget motel room "
United States
Hi Tech Travel and Tours
The price is NT$1,748
NT$1,958 total
includes taxes & fees
Dec 18 - Dec 19
Red Roof Inn Florence - Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Lake City Hotel Reviews

Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

10/10 Excellent
"My go to stay while in Fairfax. "
Gregory 1-night trip
Posted 22 hours ago
Hampton Inn & Suites Florence Center

Explore a world of travel with Expedia

Frequently asked questions

What's Lake City like for family-friendly vacations?
The budget-friendly destination of Lake City is a good choice if you've been thinking about a trip with your kids. The lake views, parks, and restaurants are just some of the things that make this an attractive family vacation spot. Take to the air and fly into Florence, SC (FLO-Florence Regional), which is located 22.2 mi (35.8 km) from the city center.
When's the best time to book a family-friendly vacation in Lake City?
The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 51°F. Average annual precipitation for Lake City is 53 inches.
What's there to see and do with your family in Lake City?
Lynches Lake Historical Society, Ronald E. McNair Life History Center, and The Bean Market are interesting attractions you and your family will enjoy exploring while you are staying in Lake City. Make sure you have lots of time for activities like Lions Park and Moore Farms Botanical Garden.