La Mesa Vacation Rentals

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Check prices for these dates

In two weeks
May 22 - May 24
In two months
Jul 3 - Jul 5
In three months
Jul 31 - Aug 2
In four months
Aug 28 - Aug 30

Our top choices for La Mesa vacation rentals

Rooftop terrace

Sentral Gaslamp Quarter

Sentral Gaslamp Quarter
4.0 star property
Downtown San Diego
9.4 out of 10, Exceptional, (883 reviews)
"Great place with great amenities "
United States
Sean
Sentral Gaslamp Quarter
Lobby sitting area

Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very Good, (361 reviews)
"Great location love the pillows "
United States
Ronen Ben
The price is NT$3,725
NT$4,200 total
includes taxes & fees
May 11 - May 12
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
Lobby

Little Italy Inn - Limited Service Apart Hotel

Little Italy Inn - Limited Service Apart Hotel
2.5 star property
Downtown San Diego
8.4 out of 10, Very Good, (121 reviews)
"Perfect stay!"
United States
Kaylee
The price is NT$3,589
NT$4,083 total
includes taxes & fees
May 11 - May 12
Little Italy Inn - Limited Service Apart Hotel
Aerial view

Wave Crest Resort

Wave Crest Resort
3.0 star property
Del Mar
9.2 out of 10, Wonderful, (153 reviews)
"Beautiful views clean property. "
United States
Irma
The price is NT$6,588
NT$8,516 total
includes taxes & fees
May 12 - May 13
Wave Crest Resort
Deluxe Studio, 1 Queen Bed (Self Check-in with Virtual Front Desk) | Individually decorated, individually furnished, laptop workspace

Kasa Gaslamp Quarter San Diego

Kasa Gaslamp Quarter San Diego
3.5 star property
Downtown San Diego
7.8 out of 10, Good, (182 reviews)
"Fantastic stay at Kasa! The room was spotless and very modern. You really can’t beat the location—it’s smack in the middle of the Gaslamp Quarter, so everything is walkable. It’s also surprisingly affordable for such a prime area. Highly recommend if you want to be where the action is!"
United States
Aurelio
The price is NT$3,258
NT$3,712 total
includes taxes & fees
May 12 - May 13
Kasa Gaslamp Quarter San Diego
Exterior

Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,075 reviews)
"Wonderful place. Clean and friendly "
United States
Iuliia
The price is NT$5,057
NT$5,863 total
includes taxes & fees
May 21 - May 22
Marriott Vacation Club®, San Diego
House (4 Bedrooms) | Interior

Explore Ramona's Vineyards: Tranquil Home w/ Yard

Explore Ramona's Vineyards: Tranquil Home w/ Yard
3.0 star property
Ramona
The price is NT$10,054
NT$22,172 total
includes taxes & fees
May 26 - May 27
Explore Ramona's Vineyards: Tranquil Home w/ Yard
Beach nearby

Coronado Beach Resort

Coronado Beach Resort
3.0 star property
Historic Downtown Coronado
9.0 out of 10, Wonderful, (790 reviews)
"Great place"
United States
scott
The price is NT$7,523
NT$8,275 total
includes taxes & fees
May 25 - May 26
Coronado Beach Resort
Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (145 reviews)
"Beautiful fully appointed rooms and excellent location."
United States
Michelle
The price is NT$4,226
NT$5,835 total
includes taxes & fees
May 19 - May 20
City24 Hotel Little Italy Mission Hills
Outdoor pool

Kasa Little Italy San Diego

Kasa Little Italy San Diego
4.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (422 reviews)
"Great place to stay when visiting San Diego. The apartment was exceptionally clean. Amenities were awesome, including the pool, workout room and massage chair. Location was perfect for visiting all the tourist attractions. Would definitely stay here again. "
United States
Tiffany
The price is NT$6,893
NT$10,628 total
includes taxes & fees
May 10 - May 11
Kasa Little Italy San Diego
Cottage (2 Bedrooms) | Interior

Walk to La Jolla Cove: Dtwn Cottage w/ Ocean View!

Walk to La Jolla Cove: Dtwn Cottage w/ Ocean View!
3.0 star property
Village of La Jolla
Walk to La Jolla Cove: Dtwn Cottage w/ Ocean View!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesa Hotel Reviews

Handlery Hotel

Handlery Hotel

10/10 Excellent
"The pool area was awesome"
Blaine 5-night trip
Posted 5 hours ago
Handlery Hotel

Find out more about La Mesa

Search for holiday rentals in La Mesa on Expedia! You can easily find your home rentals, villas, holiday apartments in La Mesa using one of the methods below:

  • View our selection of featured holiday rentals in La Mesa
  • Use the map to find apartments and other holiday homes in the La Mesa neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in La Mesa while they last

Look no further and take a look at our great range of rental properties in La Mesa!

Frequently asked questions

Are there vacation rentals in La Mesa?

Yes, you can find vacation rentals in La Mesa near La Mesa Memorial Fine Arts Center, or you can choose a secluded option if you'd like a relaxing place to stay. Visitors like the top-notch restaurants and shops in La Mesa. Leave some time to check out the zoo and entertainment venues during your trip.

How many vacation rentals are there in La Mesa?

With 68 Expedia vacation rentals, you're sure to find just the right place for your La Mesa stay.

What can I see and do in La Mesa?

Explore the area and cultural attractions such as Computer Museum of America, or visit a family-friendly sight such as San Diego Zoo. While in the area, you can also visit popular places like Mission Bay and Petco Park.

What are vacation rentals like in La Mesa?

Vacation rentals are privately owned properties you can book for several days or more in La Mesa. Vacation rentals feature amenities such as WiFi and washers and dryers so you'll have everything you need. If you're concerned about a clean environment, vacation rentals can provide a sense of safety away from shared hotel elevators and busy lobbies while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a great choice for families.