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La Mesa Vacation Rentals

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Check prices for these dates

In two weeks
Nov 6 - Nov 8
In two months
Dec 18 - Dec 20
In three months
Jan 15 - Jan 17
In four months
Feb 12 - Feb 14

Our top choices for La Mesa vacation rentals

A spacious lounge area with a sofa, a coffee table, and a bar with stools.

1. Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,256 reviews)
"Great for traveling families."
United States
Veronica Dangerfield
The price is NT$4,695
NT$5,443 total
includes taxes & fees
Nov 9 - Nov 10
Marriott Vacation Club®, San Diego
A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.

2. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (235 reviews)
"Friendly staff!"
United States
Donavin
The price is NT$3,778
NT$5,369 total
includes taxes & fees
Nov 2 - Nov 3
City24 Hotel Little Italy Mission Hills
A beach with a hotel in the background.

3. Coronado Beach Resort

Coronado Beach Resort
3.0 star property
Historic Downtown Coronado
9.2 out of 10, Wonderful, (839 reviews)
"Amazing location, amenities, staff"
United States
Javier
The price is NT$6,325
NT$6,958 total
includes taxes & fees
Nov 15 - Nov 16
Coronado Beach Resort
A spacious lobby with a sofa, chairs, a bookshelf, and a large window with a view of greenery.

4. Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very good, (499 reviews)
"We had a great stay! The room had a charming Parisian feel—compact and studio-style, but completely modern and spotlessly clean."
United States
Josh
The price is NT$3,048
NT$3,437 total
includes taxes & fees
Oct 26 - Oct 27
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
A rooftop pool with lounge chairs and a city skyline in the background.

5. Kasa Little Italy San Diego

Kasa Little Italy San Diego
4.5 star property
Downtown San Diego
9.6 out of 10, Exceptional, (551 reviews)
"Super nice amenities - would stay again. Great location"
United States
Nirmeen
The price is NT$6,219
NT$9,597 total
includes taxes & fees
Oct 27 - Oct 28
Kasa Little Italy San Diego
A modern lobby with a green sofa, a wooden accent wall, and a large plant.

6. Little Italy Inn - Limited Service Apart Hotel

Little Italy Inn - Limited Service Apart Hotel
2.5 star property
Downtown San Diego
8.4 out of 10, Very good, (376 reviews)
"great stay"
United States
alex
The price is NT$3,187
NT$3,689 total
includes taxes & fees
Oct 26 - Oct 27
Little Italy Inn - Limited Service Apart Hotel
A coastal residential area with houses, a well-maintained lawn, and a view of the ocean.

7. Wave Crest Resort

Wave Crest Resort
3.0 star property
Del Mar
9.2 out of 10, Wonderful, (163 reviews)
"wow, this is the best place ever. I had an amazing vacation. The staff was most hospitable. easy parking. I could hear the ocean at night while I slept. makes for a heavenly sleep only a 5-minute walk to the beach, but you could see the ocean from the room."
United States
Erik
The price is NT$5,962
NT$7,842 total
includes taxes & fees
Oct 26 - Oct 27
Wave Crest Resort
A modern fireplace with logs, surrounded by rustic decor including a potted plant and vases.

8. Large Group Wellness Retreat w Spa & Gym

Large Group Wellness Retreat w Spa & Gym
3.0 star property
University City
The price is NT$32,666
NT$55,173 total
includes taxes & fees
Nov 13 - Nov 14
Large Group Wellness Retreat w Spa & Gym
A modern building with a unique architectural design, featuring a balcony and a wooden deck area.

9. Stroll to Shore + Mission Blvd: Dog-friendly Home

Stroll to Shore + Mission Blvd: Dog-friendly Home
3.0 star property
Mission Beach
The price is NT$7,303
NT$19,475 total
includes taxes & fees
Oct 26 - Oct 27
Stroll to Shore + Mission Blvd: Dog-friendly Home
A neatly made bed with white and gold bedding, two bedside tables with lamps, and three wall-mounted mirrors.

10. Kasa Gaslamp Quarter San Diego

Kasa Gaslamp Quarter San Diego
3.5 star property
Downtown San Diego
7.8 out of 10, Good, (239 reviews)
"Wonderful place!"
Canada
Eric
The price is NT$3,814
NT$4,346 total
includes taxes & fees
Oct 26 - Oct 27
Kasa Gaslamp Quarter San Diego
A living room with a white sofa, two blue armchairs, a wooden coffee table, and a painting on the wall.

11. < 2 Mi to Pacific Beach! Sunny San Diego Escape

< 2 Mi to Pacific Beach! Sunny San Diego Escape
3.0 star property
Pacific Beach
7.4 out of 10, Good, (3 reviews)
"Strategic location for beach, amusement parks and restaurants. Close to major freeways and airport. House has plenty of room across the three floors. Kids loved seeing the seaworld fireworks from the open air rooftop patio. This property has it all. Owner quickly addressed any of our questions and needs. "
United States
Thomas
The price is NT$11,084
NT$24,863 total
includes taxes & fees
Nov 18 - Nov 19
< 2 Mi to Pacific Beach! Sunny San Diego Escape
A modern living room with a sofa, a TV, a floor lamp, and a large window offering a city view.

12. Rooftop w/ Views: Modern Little Italy Townhome

Rooftop w/ Views: Modern Little Italy Townhome
3.5 star property
Downtown San Diego
10.0 out of 10, Exceptional, (1 review)
The price is NT$9,226
NT$21,382 total
includes taxes & fees
Nov 22 - Nov 23
Rooftop w/ Views: Modern Little Italy Townhome
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesa Hotel Reviews

Wyndham San Diego Bayside

Wyndham San Diego Bayside

10/10 Excellent
"Staff was helpful. Location is great. You can walk to the cruise ships and to good restaurants in Little Italy,"
David Virgil 3-night trip
Posted 1 hour ago
Wyndham San Diego Bayside

Find out more about La Mesa

Search for holiday rentals in La Mesa on Expedia! You can easily find your home rentals, villas, holiday apartments in La Mesa using one of the methods below:

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Look no further and take a look at our great range of rental properties in La Mesa!

Frequently asked questions

Are there vacation rentals in La Mesa?

Yes, you can find vacation rentals in La Mesa near La Mesa Memorial Fine Arts Center, or you can choose a secluded option if you'd like a relaxing place to stay. Visitors like the top-notch restaurants and shops in La Mesa. Leave some time to check out the zoo and entertainment venues during your trip.

How many vacation rentals are there in La Mesa?

With 65 Expedia vacation rentals, you're sure to find just the right place for your La Mesa stay.

What can I see and do in La Mesa?

While exploring the area, visit family-friendly sights like San Diego Zoo, or get outside and enjoy nature at Mission Bay. While in the area, you can also visit popular places like Petco Park and Port of San Diego.

What are vacation rentals like in La Mesa?

Vacation rentals are privately owned properties you can book for several days or more in La Mesa. Vacation rentals feature amenities such as WiFi and washers and dryers so you'll have everything you need. If you're concerned about a clean environment, vacation rentals can provide a sense of safety away from shared hotel elevators and busy lobbies while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a great choice for families.