La Mesa Vacation Rentals

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Check prices for these dates

In two weeks
Dec 26 - Dec 28
In two months
Feb 6 - Feb 8
In three months
Mar 6 - Mar 8
In four months
Apr 3 - Apr 5

Our top choices for La Mesa vacation rentals

Premium bedding, pillowtop beds, desk, laptop workspace
Sentral Gaslamp Quarter

Aparthotel in Downtown San Diego

Sentral Gaslamp Quarter
4.0 star property
9.2 out of 10, Wonderful, (592)
"It was nice stay! "
United States
Chashawna
The price is NT$3,636
NT$5,120 total
includes taxes & fees
Dec 16 - Dec 17
Sentral Gaslamp Quarter
Outdoor pool
Kasa Little Italy San Diego

Aparthotel in Downtown San Diego

Kasa Little Italy San Diego
4.5 star property
9.6 out of 10, Exceptional, (351)
"Beautiful rooms, super clean and very responsive and nice staff!"
United States
Ivona
The price is NT$6,208
NT$9,811 total
includes taxes & fees
Dec 17 - Dec 18
Kasa Little Italy San Diego
Lobby sitting area
Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Aparthotel in Hillcrest

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
8.4 out of 10, Very Good, (264)
"Overall good place."
United States
Isaac
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
Exterior
City24 Hotel Little Italy Mission Hills

Aparthotel in Middletown

City24 Hotel Little Italy Mission Hills
4.5 star property
9.6 out of 10, Exceptional, (104)
"would definitely go back and stay there again "
United States
Kounwick
City24 Hotel Little Italy Mission Hills
Beach nearby
Coronado Beach Resort

Condo in Historic Downtown Coronado

Coronado Beach Resort
3.0 star property
9.0 out of 10, Wonderful, (750)
"This stay was one of our best yet! Highly recommend! Friendly staff. Great space"
United States
Sheree
The price is NT$5,822
NT$6,405 total
includes taxes & fees
Dec 21 - Dec 22
Coronado Beach Resort
Deluxe Studio, 1 Queen Bed (Self Check-in with Virtual Front Desk) | Individually decorated, individually furnished, laptop workspace
Kasa Gaslamp Quarter San Diego

Aparthotel in Downtown San Diego

Kasa Gaslamp Quarter San Diego
3.5 star property
8.0 out of 10, Very Good, (152)
"Everything was perfect about the room and location. The minor flaw was the stench in the lobby from the downstairs restaurant and bar. I loved staying here. "
United States
Chris
Kasa Gaslamp Quarter San Diego
Queen Bed Studio with Patio | Terrace/patio
Little Italy Inn - Limited Service Apart Hotel

Aparthotel in Downtown San Diego

Little Italy Inn - Limited Service Apart Hotel
2.5 star property
8.2 out of 10, Very Good, (114)
"Everything was great close to shopping and great dining"
Canada
Wendy
Little Italy Inn - Limited Service Apart Hotel
Outdoor pool, a heated pool
Wave Crest Resort

Condo in Del Mar

Wave Crest Resort
3.0 star property
9.2 out of 10, Wonderful, (142)
"Great location "
United States
Erin
The price is NT$6,401
NT$8,290 total
includes taxes & fees
Dec 15 - Dec 16
Wave Crest Resort
Condo, 2 Bedrooms | 2 bedrooms, free WiFi
Ocean View Luxury Condo

Condo in Pacific Beach

Ocean View Luxury Condo
4.0 star property
9.0 out of 10, Wonderful, (6)
"Wonderful place!!! Would stay again "
United States
Craig
Ocean View Luxury Condo
Family House, Private Bathroom | Terrace/patio
New Cozy Studio 2 Queen Beds, Kitchen Walk to Water

Vacation Home in Point Loma

New Cozy Studio 2 Queen Beds, Kitchen Walk to Water
3.0 star property
8.0 out of 10, Very Good, (1)
"The studio was beautiful, clean, and cozy. The only thing that I will say is that the pictures advertised show both the main home and the studio, so it is misleading as to what amenities are available in your own space. Other than that I enjoyed my stay and the owner was very prompt to respond to the few questions that I had."
United States
Fatimah
New Cozy Studio 2 Queen Beds, Kitchen Walk to Water
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesa Hotel Reviews

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

10/10 Excellent
"Location is amazing. Nice room. Highly recommend to stay this hotel "
kenji 1-night trip
Posted 12 hours ago
Hard Rock Hotel San Diego

Find out more about La Mesa

Search for holiday rentals in La Mesa on Expedia! You can easily find your home rentals, villas, holiday apartments in La Mesa using one of the methods below:

  • View our selection of featured holiday rentals in La Mesa
  • Use the map to find apartments and other holiday homes in the La Mesa neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in La Mesa while they last

Look no further and take a look at our great range of rental properties in La Mesa!

Frequently asked questions

Are there vacation rentals in La Mesa?

Yes, you can find vacation rentals in La Mesa near Computer Museum of America, or you can choose a secluded option if you'd like a relaxing place to stay. Visitors like the top-notch restaurants and shops in La Mesa. Leave some time to check out the zoo and entertainment venues during your trip.

How many vacation rentals are there in La Mesa?

With 59 Expedia vacation rentals, you're sure to find just the right place for your La Mesa stay.

What can I see and do in La Mesa?

Explore the area and cultural attractions such as Computer Museum of America, or visit a family-friendly sight such as San Diego Zoo. While in the area, you can also visit popular places like Petco Park and Port of San Diego.

What are vacation rentals like in La Mesa?

Vacation rentals are privately owned properties you can book for several days or more in La Mesa. Vacation rentals feature amenities such as WiFi and washers and dryers so you'll have everything you need. If you're concerned about a clean environment, vacation rentals can provide a sense of safety away from shared hotel elevators and busy lobbies while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a great choice for families.