Find hotels in South Central Houston, Houston from NT$1,834
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Discover 1,147 South Central Houston hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hotel ZaZa Houston Memorial City
Hotel ZaZa Houston Memorial City

Houston Marriott Medical Center/Museum District
Houston Marriott Medical Center/Museum District

Hampton Inn & Suites Houston-Bush Intercontinental Aprt
Hampton Inn & Suites Houston-Bush Intercontinental Aprt

Hilton Garden Inn Houston/Bush Intercontinental Airport
Hilton Garden Inn Houston/Bush Intercontinental Airport

Hotel Zaza Houston Museum District
Hotel Zaza Houston Museum District

The Westin Houston Medical Center/Museum District
The Westin Houston Medical Center/Museum District
Where to stay in South Central Houston

Downtown Houston
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

The Galleria
Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Gerald D. Hines Waterwall Park.

Texas Medical Center
Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Theater District
Travelers enjoy Theater District for its restaurants and seafood restaurants. Consider checking out Wortham Center while you're in the area.

Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Main Street Square Station.
Top South Central Houston Hotel Reviews
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Hotels in top Houston neighborhoods
- Hotels in Downtown Houston
- Hotels in The Galleria
- Hotels in Texas Medical Center
- Hotels in Theater District
- Hotels in Houston Heights
- Hotels in Houston Central Business District
- Hotels in Montrose
- Hotels in Washington Ave./ Memorial Park
- Hotels in Northside
- Hotels in Southeast Houston
- Hotels in Midtown
- Hotels in Atascocita
- Hotels in South Central Houston
- Hotels in Uptown
- Hotels in Westchase
- Hotels in Houston Museum District
- Hotels in Greater Uptown
- Hotels in Northeast Houston
- Hotels in Nassau Bay
- Hotels in Memorial
Hotels near popular Houston Attractions
- Hotels near MD Anderson Cancer Center
- Hotels near Rice University
- Hotels near University of Houston
- Hotels near Houston Zoo
- Hotels near Texas Southern University
- Hotels near Houston Natural Science Museum
- Hotels near Houston Methodist Hospital
- Hotels near Houston Museum of Fine Arts
- Hotels near Children's Museum of Houston
- Hotels near Hermann Park
More Accommodation Types in South Central Houston
South Central Houston Hotels by Star Rating
Explore more hotels
- Mint House Houston – Medical Center
- La Maison in Midtown an urban B&B
- MyCrib Houston Hostel
- Rodeway Inn & Suites Houston near Medical Center
- Wanderstay Houston Hostel
- Modern Cozy Home with King Bed
- Southmore Boulevard Motel
- Scott Inn Suites - Downtown Houston
- EaDo Signature
- Spacious Houston 3bed3 Bath Family Townhome
- Luxurious 3 Bed3 Bath Near Downtown Houston