Find hotels in Effingham, SC from NT$2,194

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Dec 23 - Dec 24
Tomorrow
Dec 24 - Dec 25
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

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Our top choices for Effingham hotels

Exterior
Quality Inn Mullins - Marion

Quality Inn Mullins - Marion

Quality Inn Mullins - Marion
2.5 star property
Marion
7.6 out of 10, Good, (375)
"It was ok clean would stay there again. "
United States
jeff
The price is NT$3,091
NT$3,369 total
includes taxes & fees
Dec 27 - Dec 28
Quality Inn Mullins - Marion
Exterior
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2201)
"Breakfast was great, room very clean ."
United States
Leann
The price is NT$2,668
NT$2,989 total
includes taxes & fees
Jan 11 - 2026/1/12
Park Inn by Radisson Florence, SC
Exterior
Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG
2.5 star property
Latta
9.6 out of 10, Exceptional, (534)
"Everything great "
Canada
Caroline
The price is NT$3,535
NT$3,853 total
includes taxes & fees
Jan 4 - 2026/1/5
Holiday Inn Express & Suites Latta by IHG
Lobby
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2510)
"I nice place to stay, very quiet, good breakfast, nice staff, spotless room. "
United States
Timothy
The price is NT$1,959
NT$2,194 total
includes taxes & fees
Dec 24 - Dec 25
Howard Johnson by Wyndham Florence
Lobby
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.2 out of 10, Wonderful, (1176)
"Great location, friendly staff. "
United States
Defelicio
The price is NT$3,059
NT$3,426 total
includes taxes & fees
Jan 11 - 2026/1/12
Comfort Inn & Suites Florence Center Area
Lobby
Best Western Executive Inn

Best Western Executive Inn

Best Western Executive Inn
2.5 star property
Latta
8.2 out of 10, Very Good, (936)
"Would definitely stay again !!!"
United States
Tracy
The price is NT$2,413
NT$2,630 total
includes taxes & fees
Jan 22 - 2026/1/23
Best Western Executive Inn
Front of property - evening/night
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
Florence
8.8 out of 10, Excellent, (1009)
"Great experience in a nice hotel in downtown."
United States
HATIM
The price is NT$3,154
NT$3,533 total
includes taxes & fees
Jan 12 - 2026/1/13
Hyatt Place Florence Downtown
Exterior
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
Florence
8.0 out of 10, Very Good, (1676)
"Clean room & breakfast was good. Checkin staff was great, friendly and professional. "
United States
Cheryl
The price is NT$2,815
NT$3,153 total
includes taxes & fees
Dec 24 - Dec 25
La Quinta Inn & Suites by Wyndham Florence
Terrace/patio
Tru by Hilton Florence I-95

Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.4 out of 10, Very Good, (1005)
"Hotel was clean , friendly staff"
United States
Gabriela
The price is NT$2,948
NT$3,413 total
includes taxes & fees
Dec 30 - Dec 31
Tru by Hilton Florence I-95
Seasonal outdoor pool
Super 8 by Wyndham Florence

Super 8 by Wyndham Florence

Super 8 by Wyndham Florence
2.0 star property
Florence
7.0 out of 10, Good, (1001)
"Clean room, Courteous Staff."
United States
Rhodney
The price is NT$1,743
NT$1,952 total
includes taxes & fees
Jan 1 - 2026/1/2
Super 8 by Wyndham Florence
Premium bedding, in-room safe, desk, iron/ironing board
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
7.8 out of 10, Good, (1258)
"Room was spotless and the staff was friendly..."
United States
Randy
The price is NT$2,444
NT$2,737 total
includes taxes & fees
Jan 21 - 2026/1/22
Quality Inn & Suites Florence Civic Center
Exterior
Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
Florence
9.0 out of 10, Wonderful, (819)
"We had our dog and the room was good and dog amenities helpful."
United States
Cynthia
The price is NT$3,535
NT$3,959 total
includes taxes & fees
Dec 31 - 2026/1/1
Hampton Inn & Suites Florence-North-I-95
Exterior
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
Florence
8.6 out of 10, Excellent, (1003)
"Room was clean, staff was courteous and breakfast was great !"
United States
Angela
The price is NT$3,598
NT$4,030 total
includes taxes & fees
Jan 4 - 2026/1/5
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Exterior
Comfort Suites Florence I-95

Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
Florence
8.4 out of 10, Very Good, (1002)
"Pool was clean good breakfast "
United States
Ann
The price is NT$3,236
NT$3,751 total
includes taxes & fees
Jan 11 - 2026/1/12
Comfort Suites Florence I-95
Lobby sitting area
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.0 out of 10, Very Good, (27)
"Friendly staff and clean environment "
United States
john
The price is NT$2,948
NT$3,427 total
includes taxes & fees
Dec 30 - Dec 31
Spark by Hilton Florence North I-95, SC
Front of property
Best Western Inn

Best Western Inn

Best Western Inn
2.5 star property
Florence
7.6 out of 10, Good, (1008)
"Spotless room and courteous staff"
United States
Krusaundra
The price is NT$2,807
NT$3,144 total
includes taxes & fees
Dec 28 - Dec 29
Best Western Inn
Free daily on-the-go breakfast
Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North
2.0 star property
Florence
6.8 out of 10, (1005)
"Clean room , quite area , walking distance "
United States
Gisell
The price is NT$1,850
NT$2,072 total
includes taxes & fees
Dec 24 - Dec 25
Days Inn by Wyndham Florence/I-95 North
Exterior
The Inn at the Crossroads

The Inn at the Crossroads

The Inn at the Crossroads
2.0 star property
Lake City
9.4 out of 10, Exceptional, (830)
"Awesome hotel stay "
United States
Jerry
The price is NT$4,230
NT$4,737 total
includes taxes & fees
Dec 24 - Dec 25
The Inn at the Crossroads
Exterior
Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence
2.0 star property
Florence
6.8 out of 10, (1003)
"Good stay "
United States
Jimmy
The price is NT$1,862
NT$2,086 total
includes taxes & fees
Dec 24 - Dec 25
Microtel Inn & Suites by Wyndham Florence
Exterior
TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
Florence
9.0 out of 10, Wonderful, (707)
"Good stay, great staff"
United States
James
The price is NT$3,131
NT$3,507 total
includes taxes & fees
Dec 28 - Dec 29
TownePlace Suites by Marriott Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Effingham Hotel Reviews

Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95

10/10 Excellent
"We had our dog and the room was good and dog amenities helpful."
Cynthia 1-night trip
Posted 17 hours ago
Hampton Inn & Suites Florence-North-I-95

More cheap stays in Effingham

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC
The price is NT$1,959 per night from Dec 24 to Dec 25
NT$1,959
NT$2,194 total
Dec 24 - Dec 25
includes taxes & fees
8.6/10 Excellent! (2,499 reviews)

Hotels in Effingham with star-rating

Frequently asked questions

Where is the best place to stay in Effingham?
Howard Johnson by Wyndham Florence, located 12.3 mi (19.8 km) from the heart of Effingham, is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Park Inn by Radisson Florence, SC and Comfort Inn & Suites Florence Center Area. See all available top hotels, or vacation rentals in Effingham.
If I need to cancel my hotel reservation in Effingham, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Effingham.
Where can I learn more about changing or cancelling my trip to Effingham?
For more details about changing or cancelling your trip to Effingham, click here.
How is it to stay in Effingham?
Travelers to Effingham will find plenty to explore and enjoy. There are 133 hotels and other accommodations in the surrounding area. Find out more about Effingham.
What should I see while I'm in Effingham?
A favorite place to visit is Lynches River State Park. You'll also find Florence National Cemetery and Florence Museum in the area. Check out what more to see and do in Expedia's Effingham guide.
What's the weather like in Effingham?
The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Effingham is 54 inches.

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