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Compare 98 hotels in Mississippi County with room rates, reviews, and availability. Most hotels are fully refundable.
Super 8 by Wyndham Charleston/Sikeston East MO
Charleston
6.6 out of 10, (611)
"Staff was great! Room was nice. "
Lana
The price is NT$2,155
NT$2,392 total
includes taxes & fees
Dec 9 - Dec 10
Quality Inn Charleston - Sikeston
Charleston
6.8 out of 10, (406)
"The staff was very friendly and accommodating "
Arturo
The price is NT$2,005
NT$2,225 total
includes taxes & fees
Dec 13 - Dec 14
Eagle Inn Charleston
Charleston
6.8 out of 10, (103)
"Middle of nowhere hotel was ok"
David
The price is NT$1,890
NT$2,097 total
includes taxes & fees
Dec 14 - Dec 15
Quality Inn Cairo I-57
Cairo
6.6 out of 10, (272)
"Break fast was excellent "
Uma
The price is NT$2,190
NT$2,431 total
includes taxes & fees
Dec 13 - Dec 14
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mississippi County Hotel Reviews
Holiday Inn Express & Suites Sikeston Southwest by IHG
10/10 Excellent
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Top cities in Mississippi County
Hotels near popular Attractions
- Hotels near Mississippi River
- Hotels near Shawnee National Forest
- Hotels near Discovery Park of America
- Hotels near Ohio River
- Hotels near Reelfoot Lake
- Hotels near Reelfoot Lake State Park
- Hotels near Ohio River Valley
- Hotels near Columbus-Belmont State Park
- Hotels near Marston Community Center
- Hotels near New Madrid Historical Museum
More Accommodation Types in Mississippi County
Hotels near Mississippi County Airports
Explore more hotels
- Super 8 by Wyndham Charleston/Sikeston East MO
- Quality Inn Charleston - Sikeston
- Drury Inn & Suites Sikeston, MO
- Hampton Inn Sikeston
- Sleep Inn at Discovery Park of America
- Days Inn and Suites by Wyndham Sikeston
- Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
- Best Western Plus Sikeston
- Pear Tree Inn Sikeston
- Hospitality House Union City I 69 / US 51
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