Find Business Hotels in Carlisle, PA

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Check availability on Carlisle Business Hotels

Tonight
Dec 22 - Dec 23
Tomorrow
Dec 23 - Dec 24
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Our top choices for Carlisle business-friendly hotels

Front of property
Microtel Inn & Suites by Wyndham Carlisle

Microtel Inn & Suites by Wyndham Carlisle

Microtel Inn & Suites by Wyndham Carlisle
2.5 star property
Carlisle
9.6 out of 10, Exceptional, (1222)
"Great, well-kept hotel: comfy rooms, everything new and clean"
United States
Dosinda
The price is NT$2,280
NT$2,531 total
includes taxes & fees
Jan 4 - 2026/1/5
Microtel Inn & Suites by Wyndham Carlisle
Standard Room, 1 Queen Bed, Non Smoking, Refrigerator & Microwave | Premium bedding, in-room safe, desk, iron/ironing board
Larkspur Landing Select Carlisle

Larkspur Landing Select Carlisle

Larkspur Landing Select Carlisle
2.5 star property
Carlisle
9.0 out of 10, Wonderful, (1006)
"Clean, quiet, lovely room, decent breakfast, enjoyed it very much."
United States
Rebecca
The price is NT$2,247
NT$2,494 total
includes taxes & fees
Jan 4 - 2026/1/5
Larkspur Landing Select Carlisle
Free daily continental breakfast
MainStay Suites Carlisle - Harrisburg

MainStay Suites Carlisle - Harrisburg

MainStay Suites Carlisle - Harrisburg
2.5 star property
Carlisle
9.0 out of 10, Wonderful, (465)
"Check in was great Bed comfy Clean everywhere"
United States
Teague
The price is NT$1,851
NT$2,055 total
includes taxes & fees
Jan 4 - 2026/1/5
MainStay Suites Carlisle - Harrisburg
Exterior
Country Inn & Suites by Radisson, Carlisle, PA

Country Inn & Suites by Radisson, Carlisle, PA

Country Inn & Suites by Radisson, Carlisle, PA
3.0 star property
Carlisle
8.0 out of 10, Very Good, (1002)
"Nice hotel"
United States
Sharon
The price is NT$2,102
NT$2,333 total
includes taxes & fees
Jan 4 - 2026/1/5
Country Inn & Suites by Radisson, Carlisle, PA
Free daily full breakfast
Best Western Carlisle

Best Western Carlisle

Best Western Carlisle
2.5 star property
Carlisle
8.4 out of 10, Very Good, (1006)
"Please desk staff, clean rooms, quiet and decent grounds for walking my service dog."
United States
Nancy
The price is NT$2,146
NT$2,382 total
includes taxes & fees
Dec 25 - Dec 26
Best Western Carlisle
Front of property
Appalachian Hotel

Appalachian Hotel

Appalachian Hotel
2.5 star property
Carlisle
7.2 out of 10, Good, (187)
"Beautiful accommodations. Comfortable bed and well kept property. Would totally recommend to anyone driving through. Super quiet area "
United States
Susan
The price is NT$1,662
NT$1,845 total
includes taxes & fees
Dec 23 - Dec 24
Appalachian Hotel
Free daily buffet breakfast
Holiday Inn Express & Suites Carlisle Southwest – I-81 by IHG

Holiday Inn Express & Suites Carlisle Southwest – I-81 by IHG

Holiday Inn Express & Suites Carlisle Southwest – I-81 by IHG
2.5 star property
Carlisle
9.2 out of 10, Wonderful, (537)
"Nice hotel "
United States
Scott
The price is NT$3,346
NT$3,714 total
includes taxes & fees
Dec 27 - Dec 28
Holiday Inn Express & Suites Carlisle Southwest – I-81 by IHG
Breakfast served
Comfort Suites Downtown Carlisle

Comfort Suites Downtown Carlisle

Comfort Suites Downtown Carlisle
2.5 star property
Carlisle Historic District
8.8 out of 10, Excellent, (931)
"Clean room, nice staff, good breakfast. "
United States
John
The price is NT$2,954
NT$3,279 total
includes taxes & fees
Jan 4 - 2026/1/5
Comfort Suites Downtown Carlisle
Suite, 1 King Bed, Non Smoking | Desk, blackout drapes, iron/ironing board, free cribs/infant beds
Comfort Inn PA Turnpike - 1-81

Comfort Inn PA Turnpike - 1-81

Comfort Inn PA Turnpike - 1-81
2.5 star property
Carlisle
9.2 out of 10, Wonderful, (1003)
"Staff was great, rooms were clean"
United States
Kyle
The price is NT$2,699
NT$2,995 total
includes taxes & fees
Dec 28 - Dec 29
Comfort Inn PA Turnpike - 1-81
Fitness facility
Sleep Inn Carlisle South

Sleep Inn Carlisle South

Sleep Inn Carlisle South
2.5 star property
Carlisle
8.2 out of 10, Very Good, (844)
"Super clean room. Restaurant within walking distance "
Canada
Carole
The price is NT$2,499
NT$2,774 total
includes taxes & fees
Jan 21 - 2026/1/22
Sleep Inn Carlisle South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Carlisle Hotel Reviews

Hampton Inn Harrisburg-East (Hershey Area)

Hampton Inn Harrisburg-East (Hershey Area)

10/10 Excellent
"Good"
Yao Tsung 2-night trip
Posted 2 days ago
Hampton Inn Harrisburg-East (Hershey Area)

Frequently asked questions

How much do business-friendly hotels in Carlisle cost?
Rates for business hotels in Carlisle range between NT$1,845 and NT$3,714 per night. No matter your budget, Expedia can help you locate the ideal space to complete the job. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Carlisle?
Carlisle has multiple business-friendly hotels with a total average guest review rating of 8.5. One of the most popular is Microtel Inn & Suites by Wyndham Carlisle. Get the job done from this 2.5-stars option, which includes a cafe and a barbecue grill. Another favorite with corporate travelers is Home2 Suites by Hilton Mechanicsburg. It has a 3-stars rating and amenities such as a barbecue grill and a swimming pool.
How many business-friendly hotels are there in Carlisle?
When work takes you to Carlisle, there are 22 business-friendly hotels to choose from. These stays combine a good location with the conveniences corporate travelers need.
What are the best cheap business-friendly hotels in Carlisle?
Microtel Inn & Suites by Wyndham Carlisle is a good choice for corporate travelers looking for a money-saving option. It has amenities like a barbecue grill and a cafe. Another thrifty stay for a work trip is Comfort Inn PA Turnpike - 1-81. Pool sun loungers and a swimming pool are two of the many conveniences here. Rates for business-friendly hotels in Carlisle start from just NT$1,845 per night, so you'll have more dollars in your pocket to spend on client entertainment. If you would like to make room for some sightseeing during your Carlisle business trip, there are lots of fun and free attractions to add to your to-do list. Sports Emporium and Army Heritage and Education Center are worth stopping by. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the top business-friendly motels in Carlisle?
Rodeway Inn Carlisle meets the needs of both corporate and leisure guests. Around 6 kilometers northeast of downtown Carlisle, you'll have access to a swimming pool, front desk services and useful business amenities.With so many cultural, dining and shopping options to discover, you might think about extending your Carlisle business trip. Sports Emporium and Carlisle Theatre are terrific places to get going on your sightseeing adventures.
Are there any family-friendly hotels in Carlisle that are also business friendly?
Taking a trip with the fam, and staying in contact with colleagues, is easy at Microtel Inn & Suites by Wyndham Carlisle. Make use of amenities like complimentary breakfast and a barbecue grill at this 2.5-stars getaway in Carlisle. Also look up Comfort Inn PA Turnpike - 1-81. Get down to business and then enjoy quality time with the little ones at this 2.5-stars property. A nearby theme park and complimentary breakfast are just the start of its many conveniences. Once you've finished work, there are tons of family-friendly attractions to visit around Carlisle. Sports Emporium and Cumberland County Historical Society Museum guarantee a good time for young and old.
Why book your business-friendly hotel in Carlisle with Expedia?
Here at Expedia, our job is to help you track down an excellent stay at the right price. From deluxe, corporate-friendly properties to affordable motor inns filled with conveniences, you'll have your next work trip planned in a few simple clicks.
How can I find cheap business-friendly hotels in Carlisle?
When you're traveling for work in Carlisle, our "business friendly" filter will help you find the ideal hotel. From dependable WiFi to concierge services and conference spaces, they come with the amenities you need for a comfortable and productive stay. Another tip? Refine your search by your budget and preferred star rating to view the most affordable options.
What is there to do in Carlisle near my business-friendly hotel?
You'll find loads of wonderful things that'll fill up your itinerary in Carlisle. Head for major attractions like Sports Emporium, Carlisle Theatre and Kings Gap Environmental Education and Training Center. Cumberland County Historical Society Museum, Williams Grove Speedway and Army Heritage and Education Center are other must-see's.

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