Photo by RVLuckyorWhat

Plan, book, travel with confidence
Better together
Save up to NT$25,000 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Top Pet-friendly Upstate South Carolina Hotels

Aloft by Marriott Greenville Downtown

5 North Laurens Street Greenville SC

1 hour drive from Clemson University

Four-legged friends will enjoy free stays and pet-approved amenities, like food and water bowls, at this city-center hotel. If you need a walk during your visit, ...

9.2/10 Wonderful! (1,001 reviews)

"Great stay"

Reviewed on 2026/7/2

La Quinta by Wyndham Haywood Mall-Near Greenville Downtown

65 W Orchard Park Dr Greenville SC

1 hour drive from Clemson University

This pet-friendly hotel welcomes dogs and cats (fees apply).

7.4/10 Good! (1,108 reviews)

"Staff was accommadable."

Reviewed on 2026/7/3

Clarion Inn

5009 Pelham Road Greenville SC

2 hours drive from Clemson University

Dogs and cats will approve of the pet-friendly amenities, such as a dog park, during their stay at this hotel (fees apply for pets).

7.8/10 Good! (1,001 reviews)

"The hotel was in the process of being converted from Best Western to Clarion. Evidence of on going construction was everywhere. Check in took way too long. The room was really not ready for people staying in it."

Reviewed on 2026/6/30

See all 3,024 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.