Photo by Visit Greenville, South Carolina

Plan, book, travel with confidence
Better together
Save up to NT$5,067 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Top Pet-friendly Upstate South Carolina Hotels

Aloft Greenville Downtown

5 North Laurens Street Greenville SC

1 hour drive from Clemson University

Dogs and cats are welcome (fees apply) at this city-center hotel offering pet-friendly amenities, like food and water bowls. While you're here, take a stroll ...

9/10 Wonderful! (1,007 reviews)

I had two rooms booked and have been asked to review each booking separately - which I will not do. We loved the hotel. Room designs were excellent as were all the furnishings. We particularly enjoyed the bar and appreciate the reasonable drink prices. The bartenders were great! Unfortunately we ...

Reviewed on 2025/11/24

La Quinta Inn & Suites by Wyndham Greenville Haywood

65 W Orchard Park Dr Greenville SC

1 hour drive from Clemson University

This hotel is pet-friendly, allowing dogs and cats with an additional fee. If you're going for a walk during your stay, swing by nearby Butler Springs Park.

7.2/10 Good! (1,126 reviews)

The staff is so friendly and they are very accommodating. Eddie from the front desk is always kind. Good breakfast

Reviewed on 2025/11/30

Best Western Greenville Airport Inn

5009 Pelham Road Greenville SC

2 hours drive from Clemson University

Dogs and cats will approve of the pet-friendly amenities, such as a dog park, during their stay at this hotel (fees apply for pets).

7.6/10 Good! (1,008 reviews)

This hotel is doing a remodel so they are in the process of offering more amenities. I have not stayed at a cleaner hotel. Our room was so sanitized that it didn't matter the construction going on I do wish they had flavored coffee creamers.

Reviewed on 2025/11/29

See all 2,897 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.