Northeast Missouri Luxury Vacations

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Top Luxury Northeast Missouri Hotels

 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 out of 5
212 N Kingshighway St. Louis MO
  • 6 min drive from St. Louis Union Station
Treat yourself to some luxurious accommodations at The Royal Sonesta Chase Park Plaza St. Louis, where you can enjoy amenities like pillowtop beds, designer ...
9/10 Wonderful! (1,001 reviews)
Dust in bathroom baseboards and on TV’s. 80 dollars for overnight parking with hotel or 40 with parking garage. Room service is convenient but a bit overpriced.

Reviewed on 2026/3/10

The Royal Sonesta Chase Park Plaza St. Louis
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
  • 34 min drive from St. Louis Union Station
Stay in the lap of luxury at Ameristar Casino Resort and Spa, where you can enjoy amenities like plush bedding, HDTVs, and more. Notable amenities include a ...
8.4/10 Very Good! (1,000 reviews)
Room was so spacious, and the bath tub was huge

Reviewed on 2026/3/9

Ameristar Casino Resort and Spa
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

5 out of 5
100 Carondelet Plaza St. Louis MO
  • 13 min drive from St. Louis Union Station
Be treated to a luxury stay at The Ritz-Carlton, St. Louis, where you can enjoy amenities like plush bedding, designer toiletries, and more. The 3 bars, fitness ...
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.