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Top Luxury South Carolina Midlands Hotels

The Ballantyne, A Luxury Collection Hotel, Charlotte

10000 Ballantyne Commons Pkwy Charlotte NC

3 hours drive from Fort Jackson

Be treated to deluxe lodging at The Ballantyne, A Luxury Collection Hotel, Charlotte, where you'll find deep soaking bathtubs and pillowtop beds. The 3 bars, ...

9.2/10 Wonderful! (1,001 reviews)

"This hotel is leagues above most large-city hotels, with the possible exceptions of a Four Seasons or Waldorf location. Simply a beautiful place with focus on details like full-marble shower walls, custom-manufactured mattresses, and thoroughly professional staff. We are looking forward to the next ..."

Reviewed on 2026/6/21

The Willcox

100 Colleton Avenue SW Aiken SC

2 hours drive from Fort Jackson

Be treated to luxurious accommodations at The Willcox, where you can enjoy amenities like pillowtop beds, premium channels, and more. Deluxe amenities at this ...

The Mantissa Hotel

130 East Carolina Ave Hartsville SC

2 hours drive from Fort Jackson

Stay in the lap of luxury at The Mantissa Hotel, where you can enjoy amenities like premium mattresses, flat-screen TVs, and more. Notable amenities include ...

9.2/10 Wonderful! (292 reviews)

"Most amazing stay! Very location to the heart of hartsville! The suites are apartment style with all of the amenities you could ever need for your stay! The staff is so kind and inviting! Already booked our next stay, can’t wait to come back!"

Reviewed on 2026/6/15

See all 3,280 properties in South Carolina Midlands

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.