
Southeast Minnesota Romantic Vacations
Book a Romantic Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to NT$25,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top Romantic Southeast Minnesota Hotels

Alexander Mansion Bed and Breakfast
274 East Broadway Winona MN
- 2 hours drive from Mayo Clinic
Enjoy a stay at this romantic bed & breakfast, featuring a garden and a terrace for couples to enjoy.
9.8/10 Exceptional! (554 reviews)
"Staying at the Alexander Mansion was like stepping back in time to a unique era in Winona history. Our host is very knowledgeable, welcoming and gracious. We were very impressed by all the attention to detail, the delicious breakfast, the lovely rooms and all the special touches that made this an ..."
Reviewed on 2026/9/28

St James Hotel, a Historic Hotel of America
406 Main St. Red Wing MN
- 2 hours drive from Mayo Clinic
If you and your special someone are ready for a getaway, you're sure to love the spa and garden at this historic hotel. You'll also appreciate the luxury bedding, ...
9.2/10 Wonderful! (1,000 reviews)
Couples like: full-service spa, bar
Travelers say...
"Beautiful historic building outfitted with modern amenities."
Reviewed on 2026/9/30

AmericInn by Wyndham Austin
1700 8th St NW Austin MN
- 2 hours drive from Mayo Clinic
Enjoy a stay at this romantic hotel, featuring a hot tub and a lobby fireplace for couples to enjoy.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
