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Top Luxury North Central Florida Hotels

Baymont By Wyndham Gainesville I-75

6901 NW 4th Boulevard Gainesville FL

21 min walk from University of Florida

Baymont By Wyndham Gainesville I-75 awaits for a deluxe vacation.

5.2/10 (1,001 reviews)

"You could tell most of the staff didn't want to be there. The TV didn't work the entire time we were there and the girl who was doing the breakfast was rude and miserable; I get being a server is difficult - I worked in the service industry for 18 years - she's either burnt out or just naturally ..."

Reviewed on 2026/5/18

Palms Garden Inn

14113 S. US Hwy 441 Lake City FL

58 min drive from University of Florida

Discover luxurious lodging at Palms Garden Inn, where you can enjoy amenities like plush bedding, premium channels, and more.

7.4/10 Good! (608 reviews)

"Quiet and private location. Gene is a great lady who gave me great local restaurant recommendations in downtown High Springs and she made check in experience a breeze. Rob is also wonderful who replaced my smoke alarm battery as soon as I told him. Taylor another lady was very helpful and respectful. ..."

Reviewed on 2026/5/18

Americas Best Value Inn Lake City

3835 West US Highway 90 Lake City FL

1 hour drive from University of Florida

Choose luxury at Americas Best Value Inn Lake City, where you can enjoy amenities like premium channels, flat-screen TVs, and more. The outdoor pool and pool ...

8.6/10 Excellent! (1,002 reviews)

"The room was as advertised. Everything worked as it should. The pool was clean and open. The breakfast consisted of fresh fruit, muffins, granola bars, tea and coffee. The ice and vending machine are located in a comfortable sitting area off the small lobby. The vending machine included personals ..."

Reviewed on 2026/5/19

See all 2,742 properties in North Central Florida

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.