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Top Luxury Mesopotamia Hotels

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls

Rodovia Br 469 Km 32 Foz do Iguaçu PR

17 hours drive from Termas de Federacion

Treat yourself to a luxury stay at Hotel das Cataratas, A Belmond Hotel, Iguassu Falls, where you can enjoy amenities like 24-hour room service, free stocked ...

9.8/10 Exceptional! (1,004 reviews)

The room was excellent, and the service throughout our stay was equally impressive. The breakfast buffet was a standout. My only real complaint is the music in the bar. While the restaurants featured lovely, venue-appropriate Brazilian music, the bar and adjoining salon blasted loud, repetitive U.S. ...

Reviewed on 2026/2/2

Iguazu Grand Resort Spa & Casino

Route 12 Km 1640 Puerto Iguazú Misiones

17 hours drive from Termas de Federacion

Pamper yourself with a luxury stay at Iguazu Grand Resort Spa & Casino, where you can enjoy amenities like Champagne service, massage services, and more. The ...

9/10 Wonderful! (612 reviews)

Great spotless hotel with many ammenitiee

Reviewed on 2026/1/30

Gran Melia Iguazú

Parque Nacional Iguazu Puerto Iguazú Misiones

17 hours drive from Termas de Federacion

Go for a luxurious stay at Gran Melia Iguazú, where you can enjoy amenities like massage services, Egyptian cotton sheets, and more. Deluxe amenities at this ...

9.2/10 Wonderful! (1,003 reviews)

This is an excellent hotel inside the national park. The staff is very friendly and provide top tier service. They also upgraded our room to water fall view room which has a stunning view of the fall. The experience is superior!

Reviewed on 2026/1/25

See all 495 properties in Mesopotamia

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.