Northeast Missouri Luxury Vacations 2026

Photo by Andrew Hershfeld

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Top Luxury Northeast Missouri Hotels

The Royal Sonesta Chase Park Plaza St. Louis

212 N Kingshighway St. Louis MO

6 min drive from St. Louis Union Station

Treat yourself to some luxurious accommodations at The Royal Sonesta Chase Park Plaza St. Louis, where you can enjoy amenities like pillowtop beds, designer ...

9.2/10 Wonderful! (1,009 reviews)

"Beautiful hotel in a great location! The pool was beautiful! The staff was amazing! Parking was extremely easy, which I was worried about in St. Louis! We didn’t have time to see a movie, but thought it was so cool having a theater in the hotel! Will definitely stay here again!"

Reviewed on 2026/8/18

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO

13 min drive from St. Louis Union Station

Be treated to a luxury stay at The Ritz-Carlton, St. Louis, where you can enjoy amenities like plush bedding, designer toiletries, and more. The 3 bars, fitness ...

9.2/10 Wonderful! (580 reviews)

"Great hotel!"

Reviewed on 2026/8/10

Moberly Inn and Suites

1200 Highway 24 East Moberly MO

1 hour drive from St. Louis Union Station

Spoil yourself with classy accommodations at Moberly Inn and Suites, where you'll enjoy amenities like premium channels and more. Notable amenities include an ...

5/10 (172 reviews)

"We did not stay there the motel was condemed The website needs to be took down"

Reviewed on 2018/11/12

See all 3,007 properties in Northeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.