
Panama Luxury Vacations
Book a Luxury Hotel + Flight or Car together to unlock savings
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- Plan, book, travel with confidence
- Better togetherSave up to NT$5,067 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top Luxury Panama Hotels

JW Marriott Panama
Calle Punta Colon, Punta Pacifica Panama City Panama
The price is NT$8,824 per night from Mar 9 to Mar 10
NT$8,824
NT$9,707 total
Mar 9 - Mar 10
includes taxes & fees
Be treated to luxurious accommodations at JW Marriott Panama, where you can enjoy amenities like massage services, 24-hour room service, and more. The 4 outdoor ...
9/10 Wonderful! (1,005 reviews)
The room was perfect
Reviewed on 2026/2/17

Bristol Panama, a Registry Collection Hotel
Avenida Aquilino de La Guardia Panama City Panama
The price is NT$6,587 per night from Mar 15 to Mar 16
NT$6,587
NT$7,246 total
Mar 15 - Mar 16
includes taxes & fees
Treat yourself to some sumptuous lodging at Bristol Panama, a Registry Collection Hotel, where you'll find deep soaking bathtubs and pillowtop beds. Notable ...
9.2/10 Wonderful! (1,003 reviews)
Great service
Reviewed on 2026/2/19

Waldorf Astoria Panama
47th St. & Uruguay Street Panama City Panama
The price is NT$6,977 per night from Mar 7 to Mar 8
NT$6,977
NT$7,674 total
Mar 7 - Mar 8
includes taxes & fees
Pamper yourself with a luxury stay at Waldorf Astoria Panama, where you can enjoy amenities like Champagne service, 24-hour room service, and more. The 2 bars, ...
8.8/10 Excellent! (1,004 reviews)
It was difficult to get the staff to clean our room daily
Reviewed on 2026/2/21
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
