Southern Minnesota Honeymoon Vacations 2026

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Top Honeymoon Southern Minnesota Hotels

Alexander Mansion Bed and Breakfast

274 East Broadway Winona MN

2 hours drive from Mayo Clinic

Stay at this B&B in Winona. Enjoy free parking, a business center, and daily housekeeping. Popular attractions Winona Arts Center and Watkins Heritage Museum ...

9.8/10 Exceptional! (555 reviews)

"Absolutely wonderful. High Victorian mansion, wonderful furniture and decor, charming hosts, fantastic, convivial breakfasts, fluffy towels, great toiletries, great guest camaraderie. It couldn't have been a better experience. I would love to stay again!!"

Reviewed on 2026/10/3

Residence Inn by Marriott Rochester Mayo Clinic Area

441 W Center St Nw Rochester MN

4 min walk from Mayo Clinic

Stay at this hotel in Rochester. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular attractions ...

8.6/10 Excellent! (211 reviews)

"Room was spotless, and her breakfast was also surprisingly good"

Reviewed on 2026/9/22

St James Hotel, a Historic Hotel of America

406 Main St. Red Wing MN

2 hours drive from Mayo Clinic

Book a stay at this spa hotel in Red Wing. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the comfy rooms in ...

9.2/10 Wonderful! (1,001 reviews)

"Loved that it’s a historic hotel so you learn something while you’re there! It’s also super close to restaurants and shops within walking distance."

Reviewed on 2026/10/3

See all 1,232 properties in Southern Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.