Top Adventure Southeast Minnesota Hotels

Kahler Grand Hotel

20 2nd Ave Sw, Rochester, MN

2 min walk from Mayo Clinic

Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...

8.2/10 Very Good! (1,604 reviews)

"Clean & Comfy and easy to get to Mayo"

Reviewed on 2025/9/19

Country Inn & Suites by Radisson, Rochester, MN

4323 Highway 52 North, West Frontage Rd, Rochester, MN

10 min drive from Mayo Clinic

Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

7.4/10 Good! (1,004 reviews)

"I have stayed here several times when in the area. The property is always clean. The staff is incredibly kind and happy to help"

Reviewed on 2025/9/14

Hotel Indigo Rochester – Mayo Clinic Area by IHG

220 S Broadway, Rochester, MN

6 min walk from Mayo Clinic

Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and ...

8.8/10 Excellent! (827 reviews)

"For anyone visiting the Mayo Clinic this location is very convenient and easily accessible. Close to good restaurants including Crave right inside the hotel and the Italian restaurant Terza next door. I am usually picky about the quality of beds and cleanliness of the washroom. The bed was extremely ..."

Reviewed on 2025/9/18

See all 932 properties in Southeast Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.