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Top Adventure Mesopotamia Hotels

Iguazu Grand Resort Spa & Casino

Route 12 Km 1640 Puerto Iguazú Misiones

17 hours drive from Termas de Federacion

Book a stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...

9/10 Wonderful! (593 reviews)

Spacious rooms, grand looking interiors.

Reviewed on 2025/12/26

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls

Rodovia Br 469 Km 32 Foz do Iguaçu PR

17 hours drive from Termas de Federacion

Book a stay at this luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff and the property ...

9.8/10 Exceptional! (1,002 reviews)

Excellent service, courteous and caring staff! Luxury redefined, and why it is worth staying at a Belmond! The only thing that was less than outstanding, was the dinner buffet - limited vegetarian options

Reviewed on 2025/12/23

Gran Melia Iguazú

Parque Nacional Iguazu Puerto Iguazú Misiones

17 hours drive from Termas de Federacion

Book a stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...

9.2/10 Wonderful! (1,002 reviews)

Incredible views, fantastic breakfast, lounge and infinity pool. Hotel employees were very helpful. Overall, hotel was nice, but rooms and hallways show age.

Reviewed on 2025/12/20

See all 490 properties in Mesopotamia

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.