The South Adults Only Vacations 2026

Photo by Jennifer Hott-Greenway

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Top Adults Only The South Hotels

Shoreline Island Resort - Exclusively Adult

14200 Gulf Boulevard Madeira Beach FL

4 hours drive from Walt Disney World® Resort

Book a stay at this beach aparthotel in Madeira Beach. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the helpful staff in our reviews. ...

9.2/10 Wonderful! (1,580 reviews)

"Great location, recliners, nice staff."

Reviewed on 2026/10/2

The Southernmost Inn - Adults Only

525 United Street Key West FL

11 hours drive from Walt Disney World® Resort

Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...

8.4/10 Very Good! (1,445 reviews)

"Very close to all the action"

Reviewed on 2026/10/2

Upper Deck Hotel and Bar - Adults Only

120 E Atol St. South Padre Island TX

Stay at this hotel in South Padre Island. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions ...

9/10 Wonderful! (257 reviews)

"Forgot our shoes and Apple Watch and they held it but also offered to ship it"

Reviewed on 2026/9/30

See all 657,617 properties in The South

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.