St. Charles County Vacations & Trips

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Top destinations in St. Charles County

A calm lake reflecting autumn trees and a rocky cliff.
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Augusta

Augusta

St. Charles County Hotel Deals

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
The price is NT$5,090 per night from Aug 9 to Aug 10
NT$5,090
NT$6,487 total
Aug 9 - Aug 10
includes taxes & fees
8.6/10 Excellent! (1,033 reviews)
"Such a beautiful hotel the only issue I have was the 21 and over swimming on the weekends.. they should open it"

Reviewed on 2026/8/4

Ameristar Casino Resort and Spa
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
The price is NT$4,354 per night from Aug 28 to Aug 29
NT$4,354
NT$5,134 total
Aug 28 - Aug 29
includes taxes & fees
8.6/10 Excellent! (4,174 reviews)
"Super clean and easy check in."

Reviewed on 2026/8/4

Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is NT$3,253 per night from Aug 23 to Aug 24
NT$3,253
NT$3,797 total
Aug 23 - Aug 24
includes taxes & fees
Clayton Plaza Hotel & Extended Stay
See all 2,611 properties in St. Charles County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a St. Charles County vacation package cost?
We make it easy to travel somewhere new, with St. Charles County vacation packages starting from as low as . You'll have the flexibility to bundle your favorite airlines, hotels and car rental. For the ultimate getaway, why not add a couple of tours and activities to your itinerary?
How do I get a cheap travel package to St. Charles County?
Crafting your own St. Charles County vacation package with Expedia is one of the easiest ways to save. We have more than 550 airlines and 1,000,000 properties worldwide. With such an extensive range to pick from, you'll have no trouble putting together your next dream vacation.
What are the top hotels in St. Charles County?
For hotels in Defiance with comfy beds and friendly service, check out Research Park Inn St Louis West – Chesterfield and Embassy Suites by Hilton St. Louis St. Charles. If you plan to visit Foristell as well, you'll get a solid night's sleep at Best Western Plus The Charles Hotel or Drury Plaza Hotel St. Louis St. Charles.
How far in advance should I book my St. Charles County vacation?
Get rewarded with the widest variety at the lowest prices by booking your vacation to St. Charles County early. Airlines typically release tickets anywhere up to a year in advance, so start locking things in ASAP. That being said, Expedia is constantly working to give you the best bargains around, so it's always a good time to book your dream vacation!
What does an Expedia St. Charles County travel package include?
From flights and hotels to rental cars, Expedia can help you shape a St. Charles County package that works for you. Heading off for a week or two? Check out a rental car, flight and hotel bundle. If you're taking a quick break, a flight and hotel deal could be what you're after. Tours and activities can be added after you've booked. Our vacation packages make it a cinch to plan and save.
What should I know before booking a St. Charles County travel package?
A package can be more affordable than separately booking all you need for your trip. For example, combine your hotels, flights and rental cars and score impressive savings. No matter your vacation goals, you're bound to find a package that matches your budget.
Can I choose my airline with a St. Charles County Expedia vacation package?
Yes — and it's easy too. Expedia has access to more than 550 partner airlines throughout the world. Our packages give you the freedom to pick from available flight, hotel or activity options that fit your needs.
If I'm not able to travel, can I cancel my St. Charles County vacation package?
It's hard to predict what the future holds, so it's comforting to know that you can cancel or change your St. Charles County vacation package. If you made your booking in the last 24 hours, you may be entitled to a refund. If it's an older booking, your hotel, airline or car rental company may charge a fee. Visit our Customer Service Portal for further details.

Stay near popular St. Charles County attractions

A brick-paved street lined with historic buildings and a yellow fire hydrant.

Historic Main Street

9.4/10 (538 reviews)
You can learn about the history of St. Charles with a trip to Historic Main Street. Check out the shops and top-notch restaurants in this family-friendly area.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.