Independent Southwest Illinois hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Tonight
Oct 8 - Oct 9Tomorrow
Oct 9 - Oct 10This weekend
Oct 9 - Oct 11Next weekend
Oct 16 - Oct 18
Save an average of 15% on thousands of hotels when you're signed in
Top Southwest Illinois Hotel Reviews
Comfort Inn Edwardsville - St. Louis
8/10 Good
"Very clean, nice breakfast and friendly staff"
Drury Plaza Hotel Mt. Vernon
10/10 Excellent
"Staff was engaging. Breakfast was enjoyable. Spa area and fitness facility were clean and more than met our needs."
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
10/10 Excellent
"Our room was very nice & bed was comfortable Easy free parking & close to highway"
The Principal Hotel
10/10 Excellent
"An experience itself! This hotel used to be a school and the project to convert it was very well executed. Clean and cozy, you won’t regret staying at this property."
Drury Inn & Suites Marion
8/10 Good
"friendly and helpful staff. Great food with many options to choose from. Great hot tub"
Country Inn & Suites by Radisson, Marion, IL
10/10 Excellent
"This is an excellent hotel to stay at. Updated, easy parking, staff is very friendly, breakfast is great, will stay at this hotel again."
Explore a world of travel with Expedia
- Hotels with smoking rooms in Southwest Illinois
- La Quinta Inn & Suites Hotels in Swansea
- Hoyleton Hotels
- Hotels near Rainbow Ranch Petting Zoo
- Hotels with an Indoor Pool in O'Fallon
- Hotels near Washington County Courthouse
- Apartments in Southwest Illinois
- Hotels with an Indoor Pool in Sparta
- New Athens Hotels
- Hotels with Hot Tubs in Carlyle
- Hotels with smoking rooms in O'Fallon
- Historic Hotels in Belleville
- Marissa Hotels
- Hotels near Governors Run Golf Course
- Hotels near Carlyle Lake
- Wyndham Hotels in Saint Libory
- Family Hotels in Mascoutah
- Hotels with a Pool in Centralia
- Resorts & Hotels with Spas in Sparta
- Freeburg Hotels
- Vacation Homes in O'Fallon
- O'fallon Hotels
- Aviston Hotels
- Pet-Friendly Hotels in Highland
- Family Hotels in O'Fallon
- Hilton Hotels in Carlyle
- Hotels with Hot Tubs in O'Fallon
- Centralia Hotels
- Sparta Hotels
- Sandoval Hotels
- Breese Hotels
- 5 Star Hotels in Shiloh
- New Baden Hotels
- Okawville Hotels
- Nashville Hotels
- Romantic Hotels in O'Fallon
- Hotels near Pyramid State Recreation Area
- Hotels near Southwestern Illinois College
- Pet-Friendly Hotels in Belleville
- Hotels with a Pool in Sparta
- 5 Star Hotels in Lebanon
- 3 Star Hotels in Odin
- Belleville Hotels
- Beach Hotels in Carlyle
- Carlyle Hotels
- Hotels with a Pool in Highland
- Visit Carlyle
- Visit Keyesport
- Rainbow Ranch Petting Zoo
- Visit Nashville
- Visit Tamaroa
- West Access Marina
- Visit Marissa
- Korte Recreation Center
- Visit Swansea
- Breese Vacations
- Pinckneyville Fairgrounds
- Visit Highland
- Visit Southwest Illinois
- Visit Mascoutah
- Visit New Athens
- Visit O'Fallon
- Nashville Vacations
- Carlyle Lake
- Visit Okawville
- Visit New Baden
- Bell Tower Park
- Visit Scott Air Force Base
- Visit Breese
- Raccoon Lake Park
- Apex Car Rentals Rental Cars in O'Fallon
- Enterprise Rental Cars in Irvington
- Car rental O'Fallon
- Advantage Rent-A-Car Rental Cars in Sparta
- Car rental Belleville
- Enterprise Rental Cars in Venedy
- Dollar Rental Cars in Aviston
- Island Car Rentals Rental Cars in Okawville
- Rental cars MidAmerica-St. Louis airport
- Enterprise Rental Cars in Steeleville
- Car rentals near Pinckneyville Fairgrounds
- Car rentals near Rainbow Ranch Petting Zoo
- Car rental Breese
- Avis Rental Cars in Tilden
- Car rental Okawville
- Auto Rent Rental Cars in Hoffman
- Car rental Freeburg
- Fox Rental Cars Rental Cars in New Baden
- Apex Car Rentals Rental Cars in Smithton
- Car rentals near Sparta Country Club