La Quinta Inn & Suites Southern Illinois Hotels

A forested valley with autumn foliage, a rocky cliff, and a sunset.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Southern Illinois La Quinta Inn & Suites

Studio Suite, Non Smoking (1 King Bed) | Pillowtop beds, desk, blackout drapes, iron/ironing board

1. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

Eastport

Taylor

NT$2,871

NT$3,301 total

includes taxes & fees

Aug 12 - Aug 13

Indoor pool, open 6:00 AM to 11:00 PM, sun loungers

Deluxe Room, 1 King Bed, Non Smoking, Jetted Tub | Desk, laptop workspace, blackout drapes, iron/ironing board

2. La Quinta Inn & Suites by Wyndham Effingham

Effingham

Alexis

NT$3,314

NT$3,711 total

includes taxes & fees

Aug 23 - Aug 24

Room, 2 Queen Beds, Non Smoking | Premium bedding, pillowtop beds, desk, iron/ironing board

3. La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

O'Fallon

Tahjae

NT$2,291

NT$2,634 total

includes taxes & fees

Sep 1 - Sep 2

Deluxe Room, 1 King Bed, Non Smoking | Premium bedding, down comforters, desk, iron/ironing board

4. La Quinta Inn & Suites by Wyndham Pontoon Beach

Granite City

Weldon

NT$3,067

NT$3,527 total

includes taxes & fees

Aug 12 - Aug 13

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top Southern Illinois Hotel Reviews

Drury Inn & Suites Marion

10/10 Excellent

"The room was clean, the staff was very friendly. Pool and hot tub was clean and nice. The breakfast, dinner and drinks were good. Love the afternoon popcorn as well."

The Principal Hotel

10/10 Excellent

"E"

Baymont by Wyndham Effingham

8/10 Good

"The king room 103 was outdated but clean. Toilet seat was loose. TV could have used a written channel guide. Bed was so comfortable! Fairly quiet. Breakfast was good and hot. Would recommend for a quick overnight stop on the road."

Drury Plaza Hotel Mt. Vernon

10/10 Excellent

"Great place to stay"

Holiday Inn Express Metropolis by IHG

10/10 Excellent

"Great stop over hotel. Comfy beds and comfy rooms. Clean and well Maintained for an older hotel building that has been refurbished."

Country Inn & Suites by Radisson, Effingham, IL

10/10 Excellent

"The hotel was clean and the rooms were comfortable. We had small children with us and were hoping to check-in early to get some nap time. They were able to get both joining rooms available for us! It was much appreciated. We also enjoyed the indoor pool and the fitness gym during our stay."

Baymont by Wyndham Marion

10/10 Excellent

"It was clean, quiet, and good parking."

Comfort Suites Fairview Heights - St. Louis

8/10 Good

"Service was good. Rooms were as expected for the price. However, one room had a bad smell that I think was coming from the tub. Swimming pool was not good. Very cloudy water and smelled of algae. Overall not bad for the price."

Explore a world of travel with Expedia

Book La Quinta Inn & Suites in Southern Illinois on Expedia.com

La Quinta Inn & Suites Southern Illinois hotels

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Southern Illinois La Quinta Inn & Suites

1. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

2. La Quinta Inn & Suites by Wyndham Effingham

3. La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

4. La Quinta Inn & Suites by Wyndham Pontoon Beach

Top Southern Illinois Hotel Reviews

Drury Inn & Suites Marion

The Principal Hotel

Baymont by Wyndham Effingham

Drury Plaza Hotel Mt. Vernon

Holiday Inn Express Metropolis by IHG

Country Inn & Suites by Radisson, Effingham, IL

Baymont by Wyndham Marion

Comfort Suites Fairview Heights - St. Louis

Explore a world of travel with Expedia