La Quinta Inn & Suites Southern Illinois Hotels

A forested valley with autumn foliage, a rocky cliff, and a sunset.

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Our top choices for Southern Illinois La Quinta Inn & Suites

A multi-story hotel with a covered entrance, stone pillars, and a parking lot.

A hotel room with a bed, desk, chair, TV, and a minibar.

A lobby with seating, a reception desk, and a snack area.

A counter with a coffee machine, condiment dispensers, and a display case with pastries.

1. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

Eastport

Paul

NT$3,104

NT$3,569 total

includes taxes & fees

Nov 1 - Nov 2

A breakfast bar with a coffee machine, a cereal dispenser, and a fruit display.

Two HP desktop computers with keyboards and mice on a granite countertop.

A hotel room with two beds, a desk, a chair, and a window with curtains.

A kitchen area with a cityscape mural on the wall, a dark wooden countertop, and red pendant lights.

2. La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

O'Fallon

Zachary

A lobby with a blue sofa, patterned cushions, a reception desk, and a mural of a moon and arch.

A breakfast bar with a microwave, coffee makers, and a fruit display.

A swimming pool with clear blue water, surrounded by lounge chairs and a tiled wall.

A hotel with a central entrance, multiple floors, and a clear sky.

3. La Quinta Inn & Suites by Wyndham Pontoon Beach

Granite City

"The room was clean, the pool and fitness room were nice after long day on road. The breakfast was good, some hot protein options. The area had the things we needed and it kept us out of St. Louis proper. Probably won’t be your best la Quinta experience but we’ve learned when traveling through/near big cities need to bump up the budget a bit to have decent room in seemingly safe area. Little things like fitness room water dispenser empty and rubbery tater tots were disappointing but not huge...

lisa

NT$3,880

NT$4,461 total

includes taxes & fees

Oct 28 - Oct 29

A La Quinta hotel with a stone facade, a covered entrance, and a parking lot.

A modern hotel lobby with a large sun-shaped artwork, multiple seating areas, and a patterned rug.

A hotel room with a large bed, a desk with a chair, a flat-screen TV, a bathtub, and framed pictures on the wall.

An indoor swimming pool with lounge chairs and a clear view of the pool area.

4. La Quinta Inn & Suites by Wyndham Effingham

Effingham

Steve

NT$3,547

NT$3,972 total

includes taxes & fees

Nov 1 - Nov 2

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Top Southern Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

10/10 Excellent

"Great room, Happy Hour food, cocktails and employees . We loved the bar, very warm and inviting. Bartender was wonderful, wish I remembered her name. The only negative is that breakfast doesn’t start until 7:00 am on weekends. A little earlier would be nice for those of us that like to hit the trail earlier or maybe a grab and go option. Would defiantly recommend!"

Holiday Inn Express Metropolis by IHG

8/10 Good

"Room was nice and clean, bed was comfortable, only issue was the bathroom was so small you couldn’t barely open the door if you were standing between the toilet and the door."

Quality Inn O'Fallon - St. Louis - Shiloh

8/10 Good

"The staff was awesome! The bathroom however had some stains on the shower curtain. It should have been washed . The bed was so very comfortable! We slept great! Thank you… The staff came right to the room when we couldn’t get the tv remote to work. Asked if we needed anything else.."

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent

"Clean room, nice pool, good breakfast"

Best Western Marion Hotel

10/10 Excellent

"Overall stay and room conditions were acceptable. Only feedback to give was that the sink had low water pressure."

Best Western Delta Inn

10/10 Excellent

"Great breakfast! The beds were so comfy! The staff was great!"

Super 8 by Wyndham Troy IL/St. Louis Area

10/10 Excellent

"Pleasantly surprised at what a nice place this was. Easy check in/checkout. Indoor pool is nice, decent size. Excellent location for highways, stores, restaurants etc. Walking distance to Golden Corral Breakfast is good because of the waffle machine"

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La Quinta Inn & Suites Southern Illinois hotels

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Southern Illinois La Quinta Inn & Suites

1. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

2. La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

3. La Quinta Inn & Suites by Wyndham Pontoon Beach

4. La Quinta Inn & Suites by Wyndham Effingham

Top Southern Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Holiday Inn Express Metropolis by IHG

Quality Inn O'Fallon - St. Louis - Shiloh

Drury Inn & Suites St. Louis O'Fallon, IL

Best Western Marion Hotel

Best Western Delta Inn

Super 8 by Wyndham Troy IL/St. Louis Area

Explore a world of travel with Expedia