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Our top choices for Southampton hotels
1. Hyatt Place Houston Medical Center
Hyatt Place Houston Medical CenterTexas Medical Center, 3 km from Southampton
9.2 out of 10, Wonderful, (2,676 reviews)
"Great stay"
Michael
The price is NT$3,700
NT$4,352 total
includes taxes & fees
Aug 28 - Aug 29
2. InterContinental Houston by IHG
InterContinental Houston by IHGTexas Medical Center, 1.7 km from Southampton
9.4 out of 10, Exceptional, (1,014 reviews)
"Great bar staff and food"
Eric
The price is NT$5,132
NT$6,641 total
includes taxes & fees
Aug 29 - Aug 30
3. Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical CenterTexas Medical Center, 1.5 km from Southampton
8.4 out of 10, Very Good, (2,124 reviews)
"Clean room, comfortable bed, and super friendly staff. Just a gew steps from Rice Village and excellent restaurants. Would definitely stay again."
melissa
The price is NT$2,561
NT$3,034 total
includes taxes & fees
Sep 6 - Sep 7
4. Hyatt House Houston Medical Center
Hyatt House Houston Medical CenterTexas Medical Center, 3 km from Southampton
9.2 out of 10, Wonderful, (1,289 reviews)
"Very reliable hotel"
Leland
The price is NT$3,986
NT$4,688 total
includes taxes & fees
Aug 27 - Aug 28
5. Blossom Hotel Houston, Curio Collection by Hilton
Blossom Hotel Houston, Curio Collection by HiltonTexas Medical Center, 2.7 km from Southampton
9.0 out of 10, Wonderful, (3,917 reviews)
"Perfect location, excellent rooms and free car service to MDA appts."
Isabel
The price is NT$4,676
NT$5,471 total
includes taxes & fees
Sep 6 - Sep 7
6. DoubleTree by Hilton Hotel Houston - Greenway Plaza
DoubleTree by Hilton Hotel Houston - Greenway PlazaGreenway Plaza-Upper Kirby, 2.4 km from Southampton
8.4 out of 10, Very Good, (1,842 reviews)
"excellent hotel"
samuel
The price is NT$2,610
NT$3,053 total
includes taxes & fees
Aug 30 - Aug 31
7. The Westin Houston Medical Center/Museum District
The Westin Houston Medical Center/Museum DistrictTexas Medical Center, 1.6 km from Southampton
9.2 out of 10, Wonderful, (1,200 reviews)
"Loved the location and hospitality of the staff. Enjoyed the restaurant in the hotel."
Stanley
The price is NT$3,594
NT$4,474 total
includes taxes & fees
Aug 30 - Aug 31
8. Home2 Suites by Hilton Houston Medical Center, TX
Home2 Suites by Hilton Houston Medical Center, TXTexas Medical Center, 3.1 km from Southampton
9.2 out of 10, Wonderful, (719 reviews)
"Rooms and facilities were clean and well maintained. Staff was pleasant and friendly."
Trene Charise
The price is NT$4,154
NT$4,860 total
includes taxes & fees
Sep 3 - Sep 4
9. Hilton Garden Inn Houston Medical Center, TX
Hilton Garden Inn Houston Medical Center, TXTexas Medical Center, 3.1 km from Southampton
9.2 out of 10, Wonderful, (1,009 reviews)
"Perfect for a quick one night stay that we had. Comfortable bed, clean room, and helpful staff."
Charity
The price is NT$3,370
NT$3,943 total
includes taxes & fees
Sep 3 - Sep 4
10. Crowne Plaza Houston Med Ctr-Galleria Area by IHG
Crowne Plaza Houston Med Ctr-Galleria Area by IHGGreenway Plaza-Upper Kirby, 1.5 km from Southampton
7.8 out of 10, Good, (1,607 reviews)
"Stay was nice’! Will stay again"
Lanita
The price is NT$2,231
NT$2,610 total
includes taxes & fees
Sep 7 - Sep 8
11. Hyatt Place Houston/Galleria
Hyatt Place Houston/Galleria5.9 km from Southampton
8.8 out of 10, Excellent, (1,589 reviews)
"I always stay at this hotel. Comfortable beds and breakfast is great!"
Natasha
The price is NT$3,136
NT$3,691 total
includes taxes & fees
Aug 28 - Aug 29
12. Hampton Inn & Suites Houston Heights I-10
Hampton Inn & Suites Houston Heights I-10Washington Ave./ Memorial Park, 6.5 km from Southampton
9.0 out of 10, Wonderful, (1,008 reviews)
"Staff was great! Amazing location and safe and clean"
Raye
The price is NT$3,370
NT$3,943 total
includes taxes & fees
Sep 13 - Sep 14
13. Hotel Zaza Houston Museum District
Hotel Zaza Houston Museum District2 km from Southampton
9.2 out of 10, Wonderful, (1,023 reviews)
"Everything was nice about our stay."
Chaniquah
The price is NT$6,602
NT$8,983 total
includes taxes & fees
Aug 26 - Aug 27
14. Drury Inn & Suites Houston Near the Galleria
Drury Inn & Suites Houston Near the GalleriaThe Galleria, 5.4 km from Southampton
9.4 out of 10, Exceptional, (1,537 reviews)
"Nice quiet evening- great breakfast selection - plenty of parking. Rooms were very clean and comfortable"
Carlice
The price is NT$2,996
NT$3,505 total
includes taxes & fees
Aug 30 - Aug 31
15. Best Western Plus Downtown Inn & Suites
Best Western Plus Downtown Inn & Suites5 km from Southampton
9.2 out of 10, Wonderful, (1,125 reviews)
"Clean rooms, friendly staff, and great breakfast."
ROMAN
The price is NT$3,765
NT$4,404 total
includes taxes & fees
Aug 31 - Sep 1
16. Courtyard By Marriott Houston Medical Center Reliant Park
Courtyard By Marriott Houston Medical Center Reliant Park2.9 km from Southampton
8.6 out of 10, Excellent, (1,010 reviews)
"Great room and convenient location"
Kelli
The price is NT$2,907
NT$3,436 total
includes taxes & fees
Aug 28 - Aug 29
17. Holiday Inn Express Houston - Galleria Area by IHG
Holiday Inn Express Houston - Galleria Area by IHGThe Galleria, 5 km from Southampton
9.4 out of 10, Exceptional, (1,022 reviews)
"Very good stay and amenities."
Michelle
The price is NT$3,887
NT$4,548 total
includes taxes & fees
Sep 4 - Sep 5
18. Home2 Suites by Hilton at the Galleria
Home2 Suites by Hilton at the GalleriaGreater Uptown, 5.6 km from Southampton
9.0 out of 10, Wonderful, (1,019 reviews)
"Great place to stay"
Tyson
The price is NT$3,370
NT$3,943 total
includes taxes & fees
Sep 4 - Sep 5
19. Hyatt Regency Houston/Galleria
Hyatt Regency Houston/Galleria5.8 km from Southampton
9.2 out of 10, Wonderful, (1,476 reviews)
"Very nice place to stay. I would definitely recommend and would stay again."
Pamela
The price is NT$4,430
NT$5,220 total
includes taxes & fees
Sep 7 - Sep 8
20. Embassy Suites by Hilton Houston Downtown Convention Center
Embassy Suites by Hilton Houston Downtown Convention Center5.8 km from Southampton
9.2 out of 10, Wonderful, (1,025 reviews)
"Lovely stay."
John
The price is NT$4,415
NT$5,166 total
includes taxes & fees
Sep 3 - Sep 4
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Southampton
Find the best Southampton areas and neighborhoods for the activities you enjoy most.
Downtown Houston
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
The Galleria
Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.
Texas Medical Center
Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.
Montrose
Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or The Chapel of St. Basil while you're exploring the area.
Photo by George Zimzores
Open Photo by George Zimzores
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.
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- Buffalo Soldiers National Museum
- Houston Museum of Fine Arts
- Visit The Galleria
- Visit West University Place
- Visit Houston Convention District
- James Turrell's Twilight Epiphany Skyscape
- Houston Methodist Hospital
- Toyota Center
- Beer Can House
- Buffalo Bayou Park
- Nrg Park
- George R. Brown Convention Center
- Menil Collection
- Visit Bellaire
- Houston JPMorgan Chase Tower
- Houston Vacations
- Hermann Park
- Houston Natural Science Museum
- Gerald D. Hines Waterwall Park
- Houston Zoo
- Rothko Chapel
- Visit Greenway Plaza-Upper Kirby
- Md Anderson Cancer Center
- Williams Tower
- Visit Houston
- Rice University
- Houston Arboretum and Nature Center
- Visit Astrodome
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