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Our top choices for Sikeston hotels with a spa

1. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (118 reviews)
"Friendly staff, great breakfast, nice amenities"
United States
Roslyn
The price is NT$3,292
NT$3,744 total
includes taxes & fees
Nov 8 - Nov 9
Fairfield Inn & Suites by Marriott Sikeston

2. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (29 reviews)
"I liked the lobby, bar and breakfast areas. The full breakfast buffet was awesome. Super nice room with kitchenette. Staff were great."
United States
Mark
The price is NT$3,553
NT$4,041 total
includes taxes & fees
Nov 8 - Nov 9
TownePlace Suites by Marriott Sikeston

3. Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (651 reviews)
"Great hotel, clean spacious room, good breakfast choice"
United Kingdom
Deborah
The price is NT$3,103
NT$3,529 total
includes taxes & fees
Nov 22 - Nov 23
Hampton Inn Sikeston

4. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.8 out of 10, Excellent, (519 reviews)
"I have always have a great stay each time I’ve been here. Beds comfortable and rooms very clean."
United States
Melissa
The price is NT$3,292
NT$3,744 total
includes taxes & fees
Nov 8 - Nov 9
Holiday Inn Express & Suites Sikeston Southwest by IHG

5. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,002 reviews)
"Awesome place will be staying in more of them"
United States
Tim
The price is NT$3,064
NT$3,523 total
includes taxes & fees
Nov 8 - Nov 9
Drury Inn & Suites Sikeston, MO

6. Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
2.5 star property
Dexter
9.6 out of 10, Exceptional, (81 reviews)
"This place is Brand new and really great!"
United States
Bryan
The price is NT$3,181
NT$3,604 total
includes taxes & fees
Nov 8 - Nov 9
Hampton Inn By Hilton Dexter

7. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,007 reviews)
"Great stay! Hot tub was enjoyable and the staff was super friendly!"
United States
Chris
The price is NT$3,259
NT$3,677 total
includes taxes & fees
Nov 8 - Nov 9
Drury Plaza Hotel Cape Girardeau Conference Center

8. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (856 reviews)
"Everything was lovely. Great room, breakfast, pool, and staff."
United States
Vonnie
The price is NT$3,181
NT$3,589 total
includes taxes & fees
Nov 8 - Nov 9
Hampton Inn Cape Girardeau I 55 East

9. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (199 reviews)
"Had a great stay friendly staff very clean facilities!"
United States
Shannon
The price is NT$2,914
NT$3,316 total
includes taxes & fees
Nov 8 - Nov 9
Tru By Hilton Cape Girardeau

10. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (556 reviews)
"The staff was very friendly and rooms were great!"
United States
Jacqueline
The price is NT$3,785
NT$4,289 total
includes taxes & fees
Nov 15 - Nov 16
Courtyard by Marriott Cape Girardeau Downtown

11. The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (699 reviews)
"Clean, quiet, comfortable room. Very comfortable beds."
United States
Renee
The price is NT$3,726
NT$4,203 total
includes taxes & fees
Nov 3 - Nov 4
The Riverview

12. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
"Perfect location, beds were awesome & staff were friendly & accommodating!"
United States
Rebecca
The price is NT$3,227
NT$3,673 total
includes taxes & fees
Nov 30 - Dec 1
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

13. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (239 reviews)
"Great hotel…!!"
United States
Carlos
The price is NT$3,297
NT$3,720 total
includes taxes & fees
Nov 8 - Nov 9
Fairfield Inn & Suites by Marriott Cape Girardeau

14. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.2 out of 10, Wonderful, (1,003 reviews)
"The stay was pleasant from start to finish. Extremely nice staff, good breakfast and convenient parking. The location was also great!"
United States
Celeste
The price is NT$2,347
NT$2,647 total
includes taxes & fees
Nov 8 - Nov 9
Pear Tree Inn Cape Girardeau West

15. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,001 reviews)
"Clean room affordable and great breakfast I would definitely go back!"
United States
Lyn
The price is NT$2,608
NT$2,757 total
includes taxes & fees
Nov 8 - Nov 9
Drury Inn & Suites Jackson MO

16. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (890 reviews)
"Breakfast was good."
United States
J
The price is NT$2,605
NT$2,819 total
includes taxes & fees
Nov 8 - Nov 9
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

17. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (1,000 reviews)
"Clean rooms, great parking, very nice staff"
United States
Shelley
The price is NT$2,601
NT$2,964 total
includes taxes & fees
Nov 8 - Nov 9
Best Western Plus Sikeston I-55

18. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (829 reviews)
"Very clean property and the staff were very accommodating."
United States
Craig
The price is NT$2,265
NT$2,582 total
includes taxes & fees
Nov 3 - Nov 4
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

19. Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (322 reviews)
"The room was nice"
United States
Fred
The price is NT$2,843
NT$3,240 total
includes taxes & fees
Nov 23 - Nov 24
Comfort Inn & Suites Sikeston I-55

20. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.0 out of 10, Very good, (1,000 reviews)
"Nice clean room"
United States
James
The price is NT$2,314
NT$2,790 total
includes taxes & fees
Nov 22 - Nov 23
Candlewood Suites Cape Girardeau by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at spa hotels in Sikeston

Find out more about Sikeston

Top Sikeston attractions for a relaxing vacation

Sikeston, Missouri, offers a charming blend of Southern hospitality and unique attractions that can enhance your spa getaway. Begin your exploration at the Sikeston Depot Museum, where you can immerse yourself in local history and culture, and perhaps take a leisurely stroll around the historic train depot grounds. After a day of sightseeing, unwind at the nearby Sikeston City Park, featuring well-maintained walking trails and serene picnic spots—perfect for relaxation. For a taste of local flavor, don’t miss the famous Lambert's Café, where you can enjoy hearty Southern cuisine and their signature "throwed rolls" experience. Adventure seekers can also take a short drive to the stunning Lake Wappapello for hiking, fishing, or simply enjoying the natural beauty of the Ozarks. When it comes to accommodations, consider staying in one of Sikeston’s comfortable hotels that often feature spa amenities, allowing for a pampering experience after a day of exploration. The attention to detail and service in these hotels cater to those seeking quality and value, ensuring that your stay is both enjoyable and rejuvenating.

Top Sikeston Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Sikeston?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers like the gourmet restaurants and popular shops in Sikeston. Enjoy the museums and riverfront during your vacation. Hotels with spas are the perfect way to break out of your daily routine and add a layer of luxury to your holiday.
What's there to see and do in Sikeston?
Experience Sikeston and visit Sikeston Depot Museum, Central Park, and Front Street Studio & Art Gallery. If you have a little extra time during your trip, you might want to make a stop at Stoddard County Civil War Memorial Cemetery and Hunter-Dawson State Historic Site.
What is a Sikeston spa hotel?
Spa hotels in Sikeston provide lodging and have an on-site spa offering services including therapies and beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.

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