A calm lake with mountains in the background.

Find Adults Only Resorts & Hotels in Seneca, SC

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Check availability on Seneca Adults Only Resorts & Hotels

Next weekend
Nov 13 - Nov 15
In two weeks
Nov 20 - Nov 22

Our top choices for Seneca adults-only hotels

A poolside area with outdoor seating and a view of a lake and forested hills.

1. Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
Seneca
9.2 out of 10, Wonderful, (291 reviews)
"nice,clean hotel."
United States
Steve
The price is NT$3,941
NT$4,335 total
includes taxes & fees
Nov 22 - Nov 23
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel dining area with a long table, multiple chairs, and a bar in the background.

2. Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (765 reviews)
"Great place to stay when visiting Clemson!"
United States
Lloyd
The price is NT$3,899
NT$4,289 total
includes taxes & fees
Dec 3 - Dec 4
Hampton Inn & Suites Seneca-Clemson Area
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

3. Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very good, (699 reviews)
"The room was clean and had no odors. But the place is seriously dated even though it was clean."
United States
Greg
The price is NT$3,072
NT$3,379 total
includes taxes & fees
Dec 1 - Dec 2
Best Western Seneca-Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.

4. Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, (795 reviews)
"Very clean room, recently renovated. Comfy bed!"
United States
Rhiannon
The price is NT$2,346
NT$2,580 total
includes taxes & fees
Dec 1 - Dec 2
Days Inn by Wyndham Seneca / Clemson Area
An outdoor patio area with a fire pit, seating, and string lights.

5. Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (902 reviews)
"Great stay!"
United States
Melissa
The price is NT$3,311
NT$3,642 total
includes taxes & fees
Dec 9 - Dec 10
Tru by Hilton Seneca Clemson
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

6. Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,002 reviews)
"Friendly front desk and bar staff. We had a really nice overnight stay."
United States
Sherry
The price is NT$3,581
NT$4,445 total
includes taxes & fees
Nov 9 - Nov 10
Lakeside Lodge Clemson
A restaurant interior with a counter, seating area, and a TV mounted on the wall.

7. Quality Inn Seneca US-123

Quality Inn Seneca US-123
2.5 star property
Seneca
8.0 out of 10, Very good, (770 reviews)
"Clean rooms clean parking area nice staff all good"
United States
Barry
The price is NT$2,631
NT$3,097 total
includes taxes & fees
Dec 1 - Dec 2
Quality Inn Seneca US-123
A cabin with a cozy interior, a wooden exterior, and a view of the forest.

8. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (120 reviews)
"Perfect location for getting away in a quiet cabin!"
United States
Lori
The price is NT$2,760
NT$4,481 total
includes taxes & fees
Dec 7 - Dec 8
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Seneca Hotel Reviews

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