Santo Domingo Vacations

Book a Hotel + Flight or Car together to unlock savings

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    Better together

    Save up to NT$5,067 when you book a flight and hotel together*
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    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Rest easy

    Plan, book, and manage your trip all in one place

Find the Best Santo Domingo Vacation Packages

Santo Domingo Hotel Deals

Hotel Santo Domingo

Hotel Santo Domingo

3 out of 5
1336 Cra. 16, Santo Domingo, Antioquia
Fully refundableReserve now, pay when you stay
The price is NT$470 per night from Jul 30 to Jul 31
NT$470
NT$470 total
Jul 30 - Jul 31
Hotel Santo Domingo
The Brown, Guatape, Autograph Collection

The Brown, Guatape, Autograph Collection

4 out of 5
El Peñol, Guatapé, Antioquia
Fully refundableReserve now, pay when you stay
The price is NT$4,801 per night from Jul 22 to Jul 23
NT$4,801
NT$4,801 total
Jul 22 - Jul 23
9/10 Wonderful! (306 reviews)
Incredible oasis of a hotel at Guatape
"The hotel was incredible, really beautiful, the pool and hot tubs were fantastic. Loved the views. The restaurant was good as well. We did the water sports and enjoyed the jet skis at the hotel as well. It felt like an oasis Highly recommend!"

Reviewed on 2025/7/13

The Brown, Guatape, Autograph Collection
BubbleSky Glamping Guatapé

BubbleSky Glamping Guatapé

3 out of 5
Guatape - El Anillo 3 kms, Ingresando por la piedra, Guatapé, Colombian Peso
8.8/10 Excellent! (65 reviews)
"Espectacular el lugar y el persoal"

Reviewed on 2025/6/16

Get rates
BubbleSky Glamping Guatapé
See all 555 properties in Santo Domingo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santo Domingo vacation package cost?
You can grab a vacation package to this destination on Expedia. But how much your vacation to Santo Domingo costs will depend on the length of stay, hotel choice and season.
What are the cheapest months to go to Santo Domingo?
April, June and September are the best times to search for cheap Santo Domingo vacation packages. Opting to travel in quieter periods means you can typically find reduced prices on accommodations and flights.
How many days is enough for Santo Domingo?
Typically, a handful of days is enough to tick off the main attractions during your Santo Domingo vacation. However, if you prefer to have some time to relax or go on day trips, consider extending your trip.
How to find the best Santo Domingo package deals?
Landing a cheap Santo Domingo package deal is a breeze with Expedia. After you've entered your destination and preferred dates under our "Packages" tab, set your budget, add a few filters and see what's available. You can tweak your search by "Amenities," "Property type," "Popular locations" and more. Order the results by "Price: low to high" to view the most economical Santo Domingo package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider going away on a weekday, when prices are generally lower.
Is it cheaper to book a Santo Domingo vacation as a package?
An Expedia vacation package could land you considerable savings when compared to booking flights and hotels individually. Better still, you can personalize your Santo Domingo escape to match your exact needs. Choose your preferred flight time, select the hotel type and add a car rental. Check out our great deals to see how much you can save.
When to book a vacation package to Santo Domingo?
If you're considering a spontaneous Santo Domingo getaway, browse our last-minute deals that can be booked up to one week before you go. Prefer not to wait until the last minute? You can land incredible deals on your hotels and flights by booking well in advance.
How to plan a trip to Santo Domingo?

  1. Pick the ideal time to travel: Your schedule, favorite season and the type of weather you enjoy can all influence your decision on when to visit Santo Domingo.
  2. Figure out your budget: Ensure you have enough money to cover everything from transportation and dining out to flights and experiences. Your accommodations will likely be the largest expense during your trip to Santo Domingo.
  3. Determine how many days away: Start by listing all the activities and sights you'd like to get to in Santo Domingo. Then, estimate how long you'll need at each, as well as any travel time.
  4. Combine your accommodations and airfare: After you've nailed down your travel dates and duration, lock in the perfect Santo Domingo vacation package for you.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.