Find Resorts & Hotels with Spas in Santee, SC

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Santee Resorts & Hotels with Spas

Next weekend
In two weeks

Top Santee Resorts & Hotels with Spas

We don't have any properties that match your exact search

Recommended hotels in Santee

Tru By Hilton Santee

2.5 star property
9.2 out of 10, Wonderful, (493)
"Everything was very nice "
The price is NT$3,027
NT$3,360 total
includes taxes & fees
Aug 10 - Aug 11
Tru By Hilton Santee

Baymont by Wyndham Santee

2.5 star property
8.0 out of 10, Very Good, (1317)
"Nice room, nice staff, nice breakfast"
The price is NT$2,248
NT$2,495 total
includes taxes & fees
Aug 4 - Aug 5
Baymont by Wyndham Santee

Days Inn by Wyndham St George

2.5 star property
7.6 out of 10, Good, (1005)
"Check on was quick and easy Room was very clean and area was quiet.we had a really good night sleep "
The price is NT$1,707
NT$1,895 total
includes taxes & fees
Aug 10 - Aug 11
Days Inn by Wyndham St George

Fairfield Inn & Suites by Marriott Santee

2.5 star property
9.8 out of 10, Exceptional, (1001)
"Excellent overnight stay"
The price is NT$3,896
NT$4,325 total
includes taxes & fees
Aug 10 - Aug 11
Fairfield Inn & Suites by Marriott Santee

Hampton Inn Santee-I-95

2.5 star property
9.6 out of 10, Exceptional, (1005)
"Great stay"
The price is NT$3,956
NT$4,392 total
includes taxes & fees
Aug 11 - Aug 12
Hampton Inn Santee-I-95

Fairfield Inn by Marriott Orangeburg

2.5 star property
8.4 out of 10, Very Good, (625)
"It was a little loud due to a family with small children, but other than that good stay"
The price is NT$2,787
NT$3,094 total
includes taxes & fees
Aug 10 - Aug 11
Fairfield Inn by Marriott Orangeburg

SureStay Hotel by Best Western Manning

2.5 star property
8.6 out of 10, Excellent, (1003)
"The hotel was a great stop on our vacation. It was a nice stay.."
The price is NT$3,417
NT$3,793 total
includes taxes & fees
Sep 1 - Sep 2
SureStay Hotel by Best Western Manning

Holiday Inn Santee by IHG

3.0 star property
8.2 out of 10, Very Good, (921)
"The staff is very friendly and accommodating. We were greeted with 2 bottles of water and some puppy biscuits for our dog. The hotel has a restaurant on site with great service. "
The price is NT$3,867
NT$4,292 total
includes taxes & fees
Aug 4 - Aug 5
Holiday Inn Santee by IHG

Comfort Inn & Suites Santee

2.5 star property
8.0 out of 10, Very Good, (1001)
"Good place to stay"
The price is NT$3,032
NT$3,365 total
includes taxes & fees
Aug 10 - Aug 11
Comfort Inn & Suites Santee

Best Western Plus Santee Inn

2.5 star property
8.8 out of 10, Excellent, (1005)
"Nice pool and great breakfast. The staff was accommodating to our requests, friendly, and attentive."
The price is NT$3,439
NT$3,818 total
includes taxes & fees
Aug 10 - Aug 11
Best Western Plus Santee Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santee Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Santee?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Travelers recommend the gourmet restaurants in Santee. Be sure to enjoy activities like fishing and golfing during your stay. Hotels with spas are a great way to break out of your routine and add a layer of luxury to your vacation.
What is the best spa hotel in Santee?
Fairfield Inn & Suites by Marriott Santee is a top spa hotel featuring an outdoor pool and a 24-hour fitness center.
How many spa hotels will I find in Santee?
Among Expedia's 36 accommodation options in Santee, there is 1 spa hotel.
What's there to see and do in Santee?
Enjoy all that Santee has to offer when you visit Santee Cooper Country Club, Santee National Golf Club, and Santee State Park. If you have a bit of extra time while you're in the area, you might want to check out Lake Marion and Santee Town Hall.
What is a Santee spa hotel?
Spa hotels in Santee provide lodging and have an on-site spa offering services such as facials and beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.