An aerial view of a coastal landscape with a dam, farmland, and dense forests.

Find Resorts & Hotels with Spas in Santee, SC

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Check availability on Santee Resorts & Hotels with Spas

Tonight
Sep 18 - Sep 19
Tomorrow
Sep 19 - Sep 20
This weekend
Sep 18 - Sep 20
Next weekend
Sep 25 - Sep 27
No exact matches found, but these alternatives could be just right

Recommended hotels in Santee

Free daily buffet breakfast
WiFi (free), bed sheets
Business center
Lobby

1. Tru By Hilton Santee

Tru By Hilton Santee
Santee
NT$3,112
NT$3,454 total
includes taxes & fees
Sep 27 - Sep 28
Tru By Hilton Santee
Free breakfast
Room, 1 King Bed, Accessible, Non Smoking | Bathroom shower
Seasonal outdoor pool
Exterior

2. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
Santee
NT$4,001
NT$4,441 total
includes taxes & fees
Sep 27 - Sep 28
Hampton Inn Santee-I-95
Exterior
Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave | Bathroom | Free toiletries, hair dryer, towels, soap
Lobby
Free daily continental breakfast

3. Best Western Plus Santee Inn

Best Western Plus Santee Inn
Santee
NT$3,660
NT$4,062 total
includes taxes & fees
Sep 27 - Sep 28
Best Western Plus Santee Inn
Desk, blackout drapes, iron/ironing board, WiFi (free)
Combined shower/tub, free toiletries, towels
Lobby
Exterior

4. Baymont by Wyndham Santee

Baymont by Wyndham Santee
Santee
NT$2,392
NT$2,655 total
includes taxes & fees
Sep 20 - Sep 21
Baymont by Wyndham Santee
Children's activities
Exterior
In-room safe, desk, laptop workspace, soundproofing
Exterior

5. Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
Santee
NT$3,413
NT$3,788 total
includes taxes & fees
Oct 18 - Oct 19
Holiday Inn Santee by IHG
Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes
Lobby
Lobby
Suite, 1 Queen Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall) | Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

6. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
Santee
NT$3,294
NT$3,656 total
includes taxes & fees
Oct 11 - Oct 12
Comfort Inn & Suites Santee
In-room safe, iron/ironing board, WiFi (free), alarm clocks
Exterior
Bathtub, free toiletries, hair dryer, towels
Business center

7. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
Santee
NT$2,036
NT$2,259 total
includes taxes & fees
Sep 20 - Sep 21
Travelodge by Wyndham Santee
Free daily full breakfast
Desk, WiFi (free), bed sheets
Lobby
Desk, WiFi (free), bed sheets

8. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
Santee
NT$1,837
NT$2,216 total
includes taxes & fees
Sep 27 - Sep 28
Quality Inn & Suites Santee I-95
Room, 2 Double Beds, Accessible, Non Smoking (Mobility) | Bathroom | Combined shower/tub, free toiletries, hair dryer (on request), towels
Lobby
Seasonal outdoor pool
Lobby

9. Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
Santee
NT$2,028
NT$2,251 total
includes taxes & fees
Sep 27 - Sep 28
Super 8 by Wyndham Santee/I-95
Desk, iron/ironing board, WiFi (free), alarm clocks
Lobby
Desk, iron/ironing board, WiFi (free), alarm clocks
Desk, iron/ironing board, WiFi (free), alarm clocks

10. Econo Lodge Santee

Econo Lodge Santee
Santee
NT$2,047
NT$2,272 total
includes taxes & fees
Oct 19 - Oct 20
Econo Lodge Santee
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Choose what matters most at spa hotels in Santee

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Santee Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Santee?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Travelers recommend the gourmet restaurants in Santee. Be sure to enjoy activities like fishing and golfing during your stay. Hotels with spas are a great way to break out of your routine and add a layer of luxury to your vacation.
What's there to see and do in Santee?
Enjoy all that Santee has to offer when you visit Santee Cooper Country Club, Santee National Golf Club, and Santee State Park. If you have a bit of extra time while you're in the area, you might want to check out Lake Marion and Santee Town Hall.
What is a Santee spa hotel?
Spa hotels in Santee provide lodging and have an on-site spa offering services such as facials and beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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