Santee River Dam on Lake Marion, South Carolina, Aerial drone view of electric power lines

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Check availability on Santee Resorts & Hotels with Spas

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Recommended hotels in Santee

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (857 reviews)
The price is NT$3,347
NT$3,715 total
includes taxes & fees
Jul 6 - Jul 7
Tru By Hilton Santee

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,000 reviews)
The price is NT$3,410
NT$3,785 total
includes taxes & fees
Jun 19 - Jun 20
Best Western Plus Santee Inn

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,470 reviews)
The price is NT$2,525
NT$2,803 total
includes taxes & fees
Jun 21 - Jun 22
Baymont by Wyndham Santee

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,002 reviews)
The price is NT$4,234
NT$4,699 total
includes taxes & fees
Jun 29 - Jun 30
Fairfield Inn & Suites by Marriott Santee

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very Good, (1,000 reviews)
The price is NT$3,126
NT$3,470 total
includes taxes & fees
Jun 21 - Jun 22
Holiday Inn Santee by IHG

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,000 reviews)
The price is NT$3,812
NT$4,232 total
includes taxes & fees
Jun 28 - Jun 29
Hampton Inn Santee-I-95

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,012 reviews)
The price is NT$3,275
NT$3,635 total
includes taxes & fees
Jun 21 - Jun 22
Comfort Inn & Suites Santee

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (740 reviews)
The price is NT$1,989
NT$2,208 total
includes taxes & fees
Jun 21 - Jun 22
Travelodge by Wyndham Santee

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (542 reviews)
The price is NT$1,748
NT$2,116 total
includes taxes & fees
Jul 8 - Jul 9
Quality Inn & Suites Santee I-95

Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
2.0 star property
Santee
6.8 out of 10, (468 reviews)
The price is NT$2,013
NT$2,234 total
includes taxes & fees
Jul 1 - Jul 2
Super 8 by Wyndham Santee/I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at spa hotels in Santee

Top Santee Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Santee?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Travelers recommend the gourmet restaurants in Santee. Be sure to enjoy activities like fishing and golfing during your stay. Hotels with spas are a great way to break out of your routine and add a layer of luxury to your vacation.
What's there to see and do in Santee?
Enjoy all that Santee has to offer when you visit Santee Cooper Country Club, Santee National Golf Club, and Santee State Park. If you have a bit of extra time while you're in the area, you might want to check out Lake Marion and Santee Town Hall.
What is a Santee spa hotel?
Spa hotels in Santee provide lodging and have an on-site spa offering services such as facials and beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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