Find Luxury Hotels in Santee, SC

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Check availability on Santee Luxury Hotels

Tonight
Jul 25 - Jul 26
Tomorrow
Jul 26 - Jul 27
This weekend
Jul 25 - Jul 27
Next weekend
Aug 1 - Aug 3

Top Santee Luxury Hotels

Red Roof Inn Santee
Relax in our stylish lobby, featuring a comfortable seating area with leather sofas and a herringbone wooden floor.

Red Roof Inn Santee

2.0 star property
6.6 out of 10, (620)
"it was clean and the staff was friendly"
The price is NT$1,907
NT$2,116 total
includes taxes & fees
Aug 21 - Aug 22
Red Roof Inn Santee
Comfort Inn & Suites Santee
Relax in this stylish living room with a sofa, armchairs, and a coffee table, perfect for unwinding.

Comfort Inn & Suites Santee

2.5 star property
8.0 out of 10, Very Good, (1010)
"Good place to stay"
The price is NT$3,117
NT$3,460 total
includes taxes & fees
Aug 3 - Aug 4
Comfort Inn & Suites Santee
Baymont by Wyndham Santee
Two single beds with white linens and a flat-screen TV are featured in this stylish room.

Baymont by Wyndham Santee

2.5 star property
8.0 out of 10, Very Good, (1326)
"Nice room, nice staff, nice breakfast"
The price is NT$2,200
NT$2,442 total
includes taxes & fees
Jul 27 - Jul 28
Baymont by Wyndham Santee
Ramada by Wyndham Santee I-95
Relax in style with a pool table and comfortable seating areas.

Ramada by Wyndham Santee I-95

2.0 star property
6.2 out of 10, (531)
"Nice clean friendly "
The price is NT$2,419
NT$2,685 total
includes taxes & fees
Aug 4 - Aug 5
Ramada by Wyndham Santee I-95
Econo Lodge
Stunning building with a brick facade, black shutters, and a welcoming porch.

Econo Lodge

2.0 star property
6.4 out of 10, (309)
"No towels and dirty sink."
The price is NT$1,769
NT$1,964 total
includes taxes & fees
Aug 10 - Aug 11
Econo Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santee Hotel Reviews

SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning

10/10 Excellent
"Clean"
Trevor 1-night trip
Posted 2 days ago
SureStay Hotel by Best Western Manning

Frequently asked questions

Are you looking for a luxury hotel for your stay in Santee?
Let Expedia help you arrange your flight to Columbia Metropolitan Airport (CAE) airport, and then choose from some places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to find what you'd like to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can help you find the best luxury hotel experience that Santee has to offer. During your visit, you might want to enjoy the restaurants and coffee shops which Santee is known for.
How many luxury hotels will I be able to find in Santee?
Lie in the lap of luxury during your getaway to Santee in one of Expedia's 8 luxury hotels.
When can I expect good weather in Santee?
Planning for the weather is an important factor for making your trip to Santee a success, especially when you're splurging. The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.
What's there to see and do in Santee?
Enjoy all that Santee has to offer and visit Santee Cooper Country Club, Santee National Golf Club, and Santee State Park. If you have a little extra time during your trip, you might want to make a stop at Lake Marion and Santee Town Hall.