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Compare 1,627 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Central Hotel Panama Casco Viejo

4.0 star property
Casco Viejo
9.0 out of 10, Wonderful, (1004)
"Excellent hotel , good breakfast, great location, would highly recommend "
United States
Glen
The price is NT$6,311
NT$6,942 total
includes taxes & fees
Dec 12 - Dec 13
Central Hotel Panama Casco Viejo

La Concordia Boutique Hotel

4.0 star property
Casco Viejo
9.6 out of 10, Exceptional, (194)
"Beautiful room Good location"
United States
Karla
The price is NT$7,383
NT$8,121 total
includes taxes & fees
Dec 12 - Dec 13
La Concordia Boutique Hotel

Hotel Coral Suites

3.5 star property
Bella Vista
9.0 out of 10, Wonderful, (1004)
"Great place for the price. "
United States
Ryan
The price is NT$2,081
NT$2,289 total
includes taxes & fees
Jan 4 - 2026/1/5
Hotel Coral Suites

Waldorf Astoria Panama

5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1002)
"I loved everything about my stay "
United States
Stephanie
The price is NT$5,610
NT$6,171 total
includes taxes & fees
Dec 16 - Dec 17
Waldorf Astoria Panama

TRYP by Wyndham Panamá Centro

3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (1006)
"Great staff and the room was very clean. "
United States
JOHNNY
The price is NT$2,788
NT$3,067 total
includes taxes & fees
Dec 9 - Dec 10
TRYP by Wyndham Panamá Centro

Gamboa Rainforest Reserve

3.5 star property
Colon
7.8 out of 10, Good, (662)
"Beautiful place to stay for one night. A little over priced for Panama but the service and the food were excellent. "
Canada
Dan
The price is NT$3,908
NT$4,299 total
includes taxes & fees
Dec 9 - Dec 10
Gamboa Rainforest Reserve

Aloft Panama

3.5 star property
San Francisco
8.8 out of 10, Excellent, (890)
"The staff was very friendly, rooms were clean and modern."
United States
Greg
The price is NT$3,655
NT$4,020 total
includes taxes & fees
Dec 15 - Dec 16
Aloft Panama

Ramada Panama Centro Via Argentina

3.0 star property
Bella Vista
7.4 out of 10, Good, (267)
"Hotel staff and rooms were good , great location "
United States
Cornelly
The price is NT$2,655
NT$2,921 total
includes taxes & fees
Dec 17 - Dec 18
Ramada Panama Centro Via Argentina

Principe Hotel and Suites

3.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1585)
"Great hotel, location, food. Highly recommend the sushi restaurant next door.. One of the best ever. "
United States
Lakshmin
The price is NT$1,562
NT$1,718 total
includes taxes & fees
Dec 27 - Dec 28
Principe Hotel and Suites

Bristol Panama, a Registry Collection Hotel

5.0 star property
Bella Vista
9.4 out of 10, Exceptional, (1000)
"Love this hotel. Busy area, but hotel and restaurant make up for it."
United States
Allen
The price is NT$5,735
NT$6,309 total
includes taxes & fees
Dec 12 - Dec 13
Bristol Panama, a Registry Collection Hotel

Novotel Panama City

4.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1013)
"From the moment i checked in everything was perfect and the staff is so friendly and welcoming, i loved my stay there."
United States
Guilllermo
The price is NT$3,065
NT$3,371 total
includes taxes & fees
Dec 9 - Dec 10
Novotel Panama City

Hotel Andros

3.0 star property
Barrio Sur
8.0 out of 10, Very Good, (153)
"I love this hotel very comfortable clean great staff and location "
United States
Keisha
The price is NT$1,167
NT$1,283 total
includes taxes & fees
Dec 9 - Dec 10
Hotel Andros

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (636)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is NT$7,240
NT$7,964 total
includes taxes & fees
Dec 12 - Dec 13
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Courtyard by Marriott Panama Metromall

4.0 star property
Cerro Viento
8.8 out of 10, Excellent, (1004)
"Conveniently located near the airport and major shopping outlets."
United States
Greg
The price is NT$3,160
NT$3,476 total
includes taxes & fees
Jan 5 - 2026/1/6
Courtyard by Marriott Panama Metromall

Mahogany Suites

2.0 star property
Rousseau
10.0 out of 10, Exceptional, (1)
"Todo ok"
Colombia
Juan
The price is NT$3,655
NT$4,020 total
includes taxes & fees
Dec 20 - Dec 21
Mahogany Suites

Hilton Garden Inn Panama City Downtown, Panama

3.5 star property
Bella Vista
8.6 out of 10, Excellent, (1000)
"Stay was ok "
United States
suhail
The price is NT$2,874
NT$3,161 total
includes taxes & fees
Dec 15 - Dec 16
Hilton Garden Inn Panama City Downtown, Panama

Hospedium Princess Hotel Panama

3.5 star property
Bella Vista
7.6 out of 10, Good, (690)
"The breakfast was great, I love the pool."
United States
Estefani
The price is NT$1,608
NT$1,769 total
includes taxes & fees
Jan 5 - 2026/1/6
Hospedium Princess Hotel Panama

Courtyard by Marriott Panama Multiplaza Mall

4.0 star property
San Francisco
8.8 out of 10, Excellent, (1002)
"Perfect stay "
United States
pedro
The price is NT$3,558
NT$3,914 total
includes taxes & fees
Jan 3 - 2026/1/4
Courtyard by Marriott Panama Multiplaza Mall

Hotel La Compañía Casco Antiguo

4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (257)
"Great location!"
United States
Erik
The price is NT$10,064
NT$11,070 total
includes taxes & fees
Dec 23 - Dec 24
Hotel La Compañía Casco Antiguo

Hampton by Hilton Panama

3.0 star property
Bella Vista
7.8 out of 10, Good, (1000)
"The hotel is good for the price , the lobby didn’t have any air conditioning,also the rooms where clean but needed to be updated , the breakfast buffet had multiple choices and it was very good . The hotel is in great location near walking distance to restaurants and stores . I will stay again. "
United States
Yusneilys amores
The price is NT$2,249
NT$2,474 total
includes taxes & fees
Dec 19 - Dec 20
Hampton by Hilton Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Rosa Hotel Reviews

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Frequently asked questions

What's the best place for a stay in Santa Rosa?
Hotel Riu Plaza Panama, located 18.8 mi (30.2 km) from the heart of Santa Rosa, is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Las Americas Golden Tower Panama and Waldorf Astoria Panama. See all available top hotels, or vacation rentals in Santa Rosa.
If I need to cancel my hotel reservation in Santa Rosa, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Rosa.
Where can I learn more about changing or cancelling my trip to Santa Rosa?
For more information about updating your trip to Santa Rosa or cancelling it, click here.
What is staying in Santa Rosa like?
Travelers to Santa Rosa will find plenty to explore and enjoy. A top sight in the area is Albrook Shopping Mall. In Santa Rosa, there are 2 hotels and other accommodations to choose from. Find out more about Santa Rosa.
What are the top places to visit in Santa Rosa?
A favorite place to visit is Chagres River. Additionally, you'll find Albrook Shopping Mall in the area. Check out what more to see and do in Expedia's Santa Rosa guide.
What's the seasonal weather like in Santa Rosa?
The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in Santa Rosa are July, August, June, and November, with each month seeing an average of 15 inches of rainfall.

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