Find hotels in Santa Clara from NT$1,429

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Our top choices for Santa Clara hotels

SAND DIAMOND HOTEL

SAND DIAMOND HOTEL
3.0 star property
Colon
8.6 out of 10, Excellent, (213)
"Good place."
United States
Tinesha
The price is NT$3,742
NT$4,116 total
includes taxes & fees
Dec 27 - Dec 28
SAND DIAMOND HOTEL

Gamboa Rainforest Reserve

Gamboa Rainforest Reserve
3.5 star property
Colon
7.8 out of 10, Good, (667)
"Beautiful place to stay for one night. A little over priced for Panama but the service and the food were excellent. "
Canada
Dan
The price is NT$4,782
NT$5,261 total
includes taxes & fees
Jan 2 - 2026/1/3
Gamboa Rainforest Reserve

Panama House Bed & Breakfast

Panama House Bed & Breakfast
2.5 star property
Bella Vista
9.0 out of 10, Wonderful, (185)
"It was a great stay in a great neighborhood with many food and beverage options, fantastic hosts and an interesting mix of people "
Canada
Brad
The price is NT$1,299
NT$1,429 total
includes taxes & fees
Dec 28 - Dec 29
Panama House Bed & Breakfast

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very Good, (1000)
"Great place and location, excellent food choices! "
United States
Francisco
The price is NT$7,166
NT$7,883 total
includes taxes & fees
Jan 8 - 2026/1/9
The Westin Playa Bonita Panama

Hotel Pension Corona

Hotel Pension Corona
2.5 star property
Calidonia
7.8 out of 10, Good, (109)
"Great spot for the price "
United States
frank
Hotel Pension Corona

Magnolia Inn

Magnolia Inn
2.0 star property
Casco Viejo
8.8 out of 10, Excellent, (417)
"Excelent location , friendly staff and cute hotel"
Canada
Renata
The price is NT$1,501
NT$1,652 total
includes taxes & fees
Dec 28 - Dec 29
Magnolia Inn

Hotel Latino

Hotel Latino
3.0 star property
Calidonia
6.6 out of 10, (220)
"I was given room key attached to a piece of plastic. It was difficult to tell exactly which room number it was. I unlocked what I thought was my room and saw someone laying in bed unaware I opened the door slightly. I closed the door and asked a housekeeper which room I was in. She told me. When I entered my room the overpowering smell of moth balls was present. I found a room elsewhere and left after an hour. Staff was nice, I didn’t feel the need to go complain but I didn’t feel secure since...
United States
Paul Andrew
Hotel Latino

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen
8.6 out of 10, Excellent, (1847)
"Better than expected: Location, transportation to and from airport, pool area tropical and comfortable. "
United States
Marty
The price is NT$3,932
NT$4,325 total
includes taxes & fees
Dec 26 - Dec 27
Riande Aeropuerto Hotel & Casino

Residencial & Hotel Palazzo

Residencial & Hotel Palazzo
3.0 star property
Calidonia
7.4 out of 10, Good, (122)
"I recommend this place"
United States
Crystal
Residencial & Hotel Palazzo

Tantalo Hotel

Tantalo Hotel
3.5 star property
Casco Viejo
8.8 out of 10, Excellent, (275)
"Staff was amazing!! Room was great as well!! "
United States
John
Tantalo Hotel

Canova

Canova
3.0 star property
Calidonia
8.2 out of 10, Very Good, (131)
"Very close place to everything. Very affordable. "
United States
Alex
The price is NT$908
NT$998 total
includes taxes & fees
Jan 8 - 2026/1/9
Canova

Holiday Inn Panama Canal by IHG

Holiday Inn Panama Canal by IHG
3.5 star property
Panama City
8.6 out of 10, Excellent, (443)
"The staff was so cordial and nice "
United States
Sonny
The price is NT$3,047
NT$3,870 total
includes taxes & fees
Dec 26 - Dec 27
Holiday Inn Panama Canal by IHG

Hotel Discovery

Hotel Discovery
2.5 star property
Calidonia
7.4 out of 10, Good, (169)
"Rooms was nice and clean. Transportation was easy area was peaceful. "
United States
Roniald
The price is NT$857
NT$943 total
includes taxes & fees
Dec 26 - Dec 27
Hotel Discovery

Hotel Plaza Herrera

Hotel Plaza Herrera
4.0 star property
Casco Viejo
10.0 out of 10, Exceptional, (14)
"Hotel Plaza Herrera is a real gem and the staff is all diamonds! We will be back! "
United States
Neal
The price is NT$9,004
NT$9,904 total
includes taxes & fees
Jan 6 - 2026/1/7
Hotel Plaza Herrera

Hotel Acapulco

Hotel Acapulco
3.0 star property
Calidonia
7.6 out of 10, Good, (127)
"Excelente"
United States
Alejandro
The price is NT$975
NT$1,072 total
includes taxes & fees
Jan 2 - 2026/1/3
Hotel Acapulco

Hotel California Panama

Hotel California Panama
3.0 star property
Bella Vista
7.8 out of 10, Good, (85)
"Excellent front desk service"
United States
JOSEPH
The price is NT$1,207
NT$1,328 total
includes taxes & fees
Dec 26 - Dec 27
Hotel California Panama

Hotel Vía España

Hotel Vía España
3.0 star property
Calidonia
6.2 out of 10, (169)
"Nice hotel conveniently placed but lots of traffic noise"
United Kingdom
Peter
Hotel Vía España

The Westin Panama

The Westin Panama
4.0 star property
Costa del Este
9.0 out of 10, Wonderful, (311)
"Great hotel and services"
United States
Pedro
The price is NT$6,733
NT$7,407 total
includes taxes & fees
Jan 10 - 2026/1/11
The Westin Panama

Hotel Montreal

Hotel Montreal
3.5 star property
Bella Vista
6.0 out of 10, (397)
"Friendly staff alright room"
Canada
Ryan
Hotel Montreal

Hotel Costa Inn

Hotel Costa Inn
3.0 star property
Calidonia
7.0 out of 10, Good, (539)
"Nice stay "
United States
AYESHA
Hotel Costa Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Santa Clara attractions

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Santa Clara awaits: its natural setting, monuments, history, and more!

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Top Santa Clara Hotel Reviews

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Frequently asked questions

What's the best place for a stay in Santa Clara?
Located 15.8 mi (25.5 km) from the heart of Santa Clara, Hotel Riu Plaza Panama is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are Las Americas Golden Tower Panama and Megapolis Hotel Panamá. See all available top hotels, or vacation rentals in Santa Clara.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.
Where can I learn more about changing or cancelling my trip to Santa Clara?
To access more information about rescheduling or cancelling your trip to Santa Clara, go to https://www.expedia.com/service/.
What's the best place to stay near Culebra Cut?
Gamboa Rainforest Reserve is one of the top choices for your stay based on our traveler data, and this 3.5-star hotel offers a marina and a full-service spa. It's located 2.9 mi (4.7 km) from Culebra Cut. Other good options within 5 miles include Canopy Bed & Breakfast and Casa en Gamboa al lado Canal de Panama.
What is staying in Santa Clara like?
Visitors can enjoy all that Santa Clara has to offer including its monuments. A top sight in the area is Albrook Shopping Mall. There are 1675 hotels and other accommodations in the surrounding area. Find out more about Santa Clara.
What is there to see in Santa Clara?
A favorite place to visit is Culebra Cut. Additionally, you'll find Albrook Shopping Mall in the area. Check out what more to see and do in Expedia's Santa Clara guide.
What's the seasonal weather like in Santa Clara?
The hottest months are usually April and March with an average temp of 79°F, while the coldest months are January and February with an average of 78°F. The rainiest months in Santa Clara are July, August, November, and October, with each month seeing an average of 11 inches of rainfall.