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Compare 33 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Santa Ana hotels

Hotel Casa Isabelita

3.0 star property
9.0 out of 10, Wonderful, (2)
"No mirror in the bathroom No fridge in the room"
Hotel Casa Isabelita

La Casa Amarilla

3.0 star property
8.8 out of 10, Excellent, (45)
"We loved the cada amarilla , the staff , the breakfast, the room , the location , everything went well thank you Carmen "
The price is NT$1,967
NT$1,967 total
Aug 29 - Aug 30
La Casa Amarilla

Hotel Archangelus

3.0 star property
10.0 out of 10, Exceptional, (1)
"Absolutely delightful! The staff were helpful and pleasant, the room was well appointed, and the breakfast served was delicious. This was my favorite accommodation during my week in Colombia and I highly recommend it."
The price is NT$1,708
NT$3,226 total
Aug 29 - Aug 30
Hotel Archangelus

LITERATIUM

3.0 star property
9.2 out of 10, Wonderful, (9)
"Loved the hotel boutique it is comfortable and beautiful. The hostess Marta1, Marta2, and Antony are lovely they make us feel like home. The rooms are comfortable and beautiful again. We fully recommend the place."
The price is NT$2,101
NT$2,101 total
Aug 29 - Aug 30
LITERATIUM

Hotel Jardines Evans By Geh Suites

3.0 star property
4.0 out of 10, (1)
"Hotel modesto, personal muy amable, pero MUY CARO por lo que ofrece, "
Hotel Jardines Evans By Geh Suites

Hotel Casa Evan

2.0 star property
8.0 out of 10, Very Good, (1)
The price is NT$1,571
NT$1,571 total
Aug 29 - Aug 30
Hotel Casa Evan

BOHEMIA HOTEL BOUTIQUE

2.5 star property
4.0 out of 10, (1)
The price is NT$2,773
NT$2,773 total
Aug 29 - Aug 30
BOHEMIA HOTEL BOUTIQUE

Hotel Santa Bárbara Mompox

2.0 star property
Hotel Santa Bárbara Mompox

Bioma Boutique Hotel

3.0 star property
9.4 out of 10, Exceptional, (52)
"Great service! The pool has shade most of the day therefore it’s great for a cool dip. The only down is the breakfast becouse the lack of choices and repetitive."
Bioma Boutique Hotel

Albarrada Hotel Boutique

3.0 star property
10.0 out of 10, Exceptional, (2)
Albarrada Hotel Boutique

Portal de la Marquesa

3.5 star property
8.8 out of 10, Excellent, (130)
"Amazing staff and beautiful location. We love it I will be back in November :-)"
Portal de la Marquesa

San Rafael

3.5 star property
9.8 out of 10, Exceptional, (20)
"Excellent place allowing for complete rest with an attentive and friendly and helpful team on all levels: mangement, reception, housekeeping ... Generous rooms and services, highly professional, too. "
The price is NT$3,390
NT$3,390 total
Sep 13 - Sep 14
San Rafael

Karakalí Boutique Hotel

3.0 star property
10.0 out of 10, Exceptional, (6)
"Excellent hotel and stay. We highly recommend it. "
The price is NT$3,385
NT$3,385 total
Sep 7 - Sep 8
Karakalí Boutique Hotel

La Gloria Hotel by BespokeColombia

3.5 star property
9.4 out of 10, Exceptional, (40)
"Nice staff and rooms. "
The price is NT$2,563
NT$2,563 total
Sep 3 - Sep 4
La Gloria Hotel by BespokeColombia

LA CANDELARIA ROOM HOUSE

3.0 star property
The price is NT$1,593
NT$1,593 total
Aug 30 - Aug 31
LA CANDELARIA ROOM HOUSE

hostal la momposina

2.0 star property
2.0 out of 10, (1)
"This is the worst hotel experience ever. They said they didn’t have our (prepaid!) reservation, and we should simply pay for a new room in cash. We arrived on the last day of the year with 2 small kids, but the owner was very very rude. He didn’t even do an extra search for our reservation. We ended up leaving. The hotels.com chat function didn’t work for us so unfortunately the hotel did receive our prepaid funds; they get our honest review in return. I sincerly recommend not going to this...
The price is NT$1,230
NT$1,230 total
Aug 29 - Aug 30
hostal la momposina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Where is the best place to stay in Santa Ana?

Portal de la Marquesa, located 18.3 mi (29.4 km) from the heart of Santa Ana, is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are Bioma Boutique Hotel and La Gloria Hotel by BespokeColombia. See all available top hotels, or vacation rentals in Santa Ana.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If your reservation is non-refundable, you may still be able to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Ana.

Where can I learn more about changing or cancelling my trip to Santa Ana?

To find more details about updating your trip to Santa Ana or cancelling it, click here.

What's it like to stay in Santa Ana?

Visitors are sure to enjoy all that Santa Ana has to offer. There are 31 hotels and other accommodations in the surrounding area. Find out more about Santa Ana.

What is there to see in Santa Ana?

A favorite place to visit is Magdalena River. You'll also find Church of the Immaculate Conception and Church of St. Francis in the area. Check out what more to see and do in Expedia's Santa Ana guide.

What's the weather like in Santa Ana?

The hottest months are usually February and March with an average temp of 84°F, while the coldest months are November and December with an average of 80°F. The rainiest months in Santa Ana are May, August, October, and September, with each month seeing an average of 14 inches of rainfall.