Find hotels near Sanford USD Medical Center, Sioux Falls from NT$1,691

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Dec 11 - Dec 12
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Dec 12 - Dec 13
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Dec 12 - Dec 14
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Dec 19 - Dec 21

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Our top choices for Sanford USD Medical Center hotels

Interior detail
Hotel On Phillips

Hotel On Phillips

Hotel On Phillips
2.5 star property
Downtown Sioux Falls, 1.8 km from Sanford USD Medical Center
9.6 out of 10, Exceptional, (1296)
"Great staff and location!"
United States
Gerald
Hotel On Phillips
Terrace/patio
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
3.0 star property
University Heights, 0.1 km from Sanford USD Medical Center
9.4 out of 10, Exceptional, (584)
"This is a great hotel - centrally located and very clean and quiet. Will definitely be staying there again. "
United States
Tracey
The price is NT$3,218
NT$3,592 total
includes taxes & fees
Dec 20 - Dec 21
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
Exterior detail
Clubhouse Hotel Suites Sioux Falls

Clubhouse Hotel Suites Sioux Falls

Clubhouse Hotel Suites Sioux Falls
3.0 star property
Mall District, 2.9 km from Sanford USD Medical Center
9.4 out of 10, Exceptional, (1000)
"Absolutely beautiful places to stay with family excellent service staff great food service great hospitality great "
United States
Rosario
Clubhouse Hotel Suites Sioux Falls
Meeting facility
Canopy By Hilton Sioux Falls Downtown

Canopy By Hilton Sioux Falls Downtown

Canopy By Hilton Sioux Falls Downtown
4.0 star property
Downtown Sioux Falls, 2.4 km from Sanford USD Medical Center
9.4 out of 10, Exceptional, (153)
"Room was very clean, great overall stay."
United States
Destiny
The price is NT$4,067
NT$4,649 total
includes taxes & fees
Jan 1 - 2026/1/2
Canopy By Hilton Sioux Falls Downtown
Meeting facility
Hilton Garden Inn Sioux Falls Downtown

Hilton Garden Inn Sioux Falls Downtown

Hilton Garden Inn Sioux Falls Downtown
3.0 star property
Downtown Sioux Falls, 2 km from Sanford USD Medical Center
9.0 out of 10, Wonderful, (882)
"Friendly front desk staff, clean room, great location, safe "
United States
Hannah
The price is NT$3,413
NT$3,931 total
includes taxes & fees
Dec 17 - Dec 18
Hilton Garden Inn Sioux Falls Downtown
Porch
Historic Victorian Inn

Historic Victorian Inn

Historic Victorian Inn
3.0 star property
Cathedral, 1.4 km from Sanford USD Medical Center
8.8 out of 10, Excellent, (56)
"It was a great place to stay and super interesting."
United States
Kathy
The price is NT$3,382
NT$4,221 total
includes taxes & fees
Dec 18 - Dec 19
Historic Victorian Inn
Exterior
Holiday Inn Sioux Falls-City Centre by IHG

Holiday Inn Sioux Falls-City Centre by IHG

Holiday Inn Sioux Falls-City Centre by IHG
3.0 star property
Downtown Sioux Falls, 1.8 km from Sanford USD Medical Center
8.6 out of 10, Excellent, (1001)
"Always a great stay. "
United States
Shawn
The price is NT$2,838
NT$3,175 total
includes taxes & fees
Dec 21 - Dec 22
Holiday Inn Sioux Falls-City Centre by IHG
Lobby
Sheraton Sioux Falls Hotel & Convention Center

Sheraton Sioux Falls Hotel & Convention Center

Sheraton Sioux Falls Hotel & Convention Center
4.0 star property
Northwest Sioux Falls, 2.8 km from Sanford USD Medical Center
8.6 out of 10, Excellent, (1000)
"Great hotel. Staff was excellent "
United States
Kristina
The price is NT$3,022
NT$3,377 total
includes taxes & fees
Jan 11 - 2026/1/12
Sheraton Sioux Falls Hotel & Convention Center
Exterior
Country Inn & Suites by Radisson, Sioux Falls, SD

Country Inn & Suites by Radisson, Sioux Falls, SD

Country Inn & Suites by Radisson, Sioux Falls, SD
3.0 star property
Downtown Sioux Falls, 1.9 km from Sanford USD Medical Center
8.4 out of 10, Very Good, (1152)
"It was a great place to stay!"
United States
Trinity
The price is NT$3,154
NT$3,522 total
includes taxes & fees
Jan 1 - 2026/1/2
Country Inn & Suites by Radisson, Sioux Falls, SD
Suite 2 Queens, Recliner, Pullout Sofa | Free WiFi, bed sheets
The Center Inn

The Center Inn

The Center Inn
2.5 star property
All Saints, 2.3 km from Sanford USD Medical Center
8.4 out of 10, Very Good, (699)
"Clean room and friendly staff."
United States
Betty
The Center Inn
3 indoor pools, open 9:00 AM to 10:00 PM, sun loungers
Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
3.0 star property
Northwest Sioux Falls, 2.9 km from Sanford USD Medical Center
7.8 out of 10, Good, (1451)
"Great staff "
United States
Eric
The price is NT$1,866
NT$2,110 total
includes taxes & fees
Dec 14 - Dec 15
Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
Basic Studio, 1 King Bed | Desk, free WiFi, wheelchair access
Valley Inn

Valley Inn

Valley Inn
2.5 star property
University Heights, 0.1 km from Sanford USD Medical Center
7.6 out of 10, Good, (1000)
"Room was clean, staff was friendly, very convenient location "
United States
Theresa
Valley Inn
Pool
Ramada by Wyndham Sioux Falls Arpt & Suites

Ramada by Wyndham Sioux Falls Arpt & Suites

Ramada by Wyndham Sioux Falls Arpt & Suites
2.0 star property
Northwest Sioux Falls, 2.9 km from Sanford USD Medical Center
7.0 out of 10, Good, (51)
"Great "
United States
Jorge
Ramada by Wyndham Sioux Falls Arpt & Suites
Lobby
Ramada by Wyndham Sioux Falls

Ramada by Wyndham Sioux Falls

Ramada by Wyndham Sioux Falls
2.0 star property
2.7 km from Sanford USD Medical Center
5.6 out of 10, (1001)
"Good room for the price."
United States
Michael
The price is NT$1,484
NT$1,691 total
includes taxes & fees
Jan 11 - 2026/1/12
Ramada by Wyndham Sioux Falls
50-inch flat-screen TV with cable channels, fireplace, Netflix
Historic Twin Tudors Inn

Historic Twin Tudors Inn

Historic Twin Tudors Inn
3.0 star property
1.3 km from Sanford USD Medical Center
8.8 out of 10, Excellent, (3)
"Lovely place! Wish we could have stayed longer. Steve was attentive and helpful. "
United States
Anonymous traveler
The price is NT$8,391
NT$9,515 total
includes taxes & fees
Dec 14 - Dec 15
Historic Twin Tudors Inn
Double Room, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout drapes
Highpoint Hotel

Highpoint Hotel

Highpoint Hotel
3.0 star property
University Heights, 0.3 km from Sanford USD Medical Center
The price is NT$5,248
NT$5,819 total
includes taxes & fees
Dec 17 - Dec 18
Highpoint Hotel
Exterior
Staybridge Suites Sioux Falls Southwest by IHG

Staybridge Suites Sioux Falls Southwest by IHG

Staybridge Suites Sioux Falls Southwest by IHG
3.0 star property
South Sioux Falls, 5.3 km from Sanford USD Medical Center
9.6 out of 10, Exceptional, (455)
"We choose to continue to stay at the Sioux Falls Staybridge because of the excellent service we receive!"
United States
Vicki
The price is NT$2,806
NT$3,141 total
includes taxes & fees
Jan 1 - 2026/1/2
Staybridge Suites Sioux Falls Southwest by IHG
Indoor pool
Comfort Inn & Suites at Sanford Sports Complex

Comfort Inn & Suites at Sanford Sports Complex

Comfort Inn & Suites at Sanford Sports Complex
2.5 star property
Northwest Sioux Falls, 6 km from Sanford USD Medical Center
9.6 out of 10, Exceptional, (891)
"We had a quick overnight as part of a longer trip but the hotel was very clean, rooms were comfortable and breakfast got us on the road. Would stay here again! "
United States
chris
The price is NT$2,946
NT$3,295 total
includes taxes & fees
Dec 28 - Dec 29
Comfort Inn & Suites at Sanford Sports Complex
Terrace/patio
Hyatt Place Sioux Falls South

Hyatt Place Sioux Falls South

Hyatt Place Sioux Falls South
3.0 star property
Mall District, 3.8 km from Sanford USD Medical Center
9.4 out of 10, Exceptional, (1003)
"Great location for travel. Various dining options close by."
United States
Russell
The price is NT$3,761
NT$4,188 total
includes taxes & fees
Dec 21 - Dec 22
Hyatt Place Sioux Falls South
Lobby sitting area
Comfort Inn & Suites Avera Southwest

Comfort Inn & Suites Avera Southwest

Comfort Inn & Suites Avera Southwest
2.5 star property
South Sioux Falls, 5.6 km from Sanford USD Medical Center
9.4 out of 10, Exceptional, (1004)
"great location to stay."
United States
Tammy
The price is NT$3,271
NT$3,650 total
includes taxes & fees
Jan 1 - 2026/1/2
Comfort Inn & Suites Avera Southwest
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Sanford USD Medical Center Hotel Reviews

Baymont by Wyndham Sioux Falls

Baymont by Wyndham Sioux Falls

10/10 Excellent
"Smooth check in. Very clean room"
William 1-night trip
Posted 3 days ago
Baymont by Wyndham Sioux Falls

Hotels near other Sanford USD Medical Center attractions

Sioux Empire Medical Museum

You can spend time studying the exhibits at Sioux Empire Medical Museum in Sioux Falls. In the area, take in the entertainment choices and beautiful waterfalls.
See properties

University of Sioux Falls

4.1/5 (170 reviews)
Take a campus tour or just explore the area of University of Sioux Falls, during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.
See properties

Frequently asked questions

What's the area like around Sanford USD Medical Center?
Sanford USD Medical Center is located in a welcoming area of Sioux Falls known for its beautiful waterfalls and sporting events. If you're looking for a convenient place to stay, check out the 112 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to Sanford USD Medical Center?
Adjacent to Sanford USD Medical Center, Valley Inn is one of the top choices for your stay based on our traveler data, and this hotel offers free parking and free WiFi. Another good choice is Home2 Suites By Hilton Sioux Falls/Sanford Medical Center, located just 0.1 mi (0.1 km) away.
How many hotels should I expect to find close to Sanford USD Medical Center?
Expedia has 112 hotels and other accommodations within a mile from Sanford USD Medical Center.
If I need to cancel the hotel reservation for my stay near Sanford USD Medical Center, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to get the best deals available near Sanford USD Medical Center.
Where can I learn more about changing or cancelling my trip in the area near Sanford USD Medical Center?
To find more details about updating your stay near Sanford USD Medical Center or cancelling it, go to https://www.expedia.com/service/.
What can I see and do near Sanford USD Medical Center?
Study the collections at Washington Pavilion of Arts and Science, Center for Western Studies, or Pettigrew Home and Museum. Spend some time wandering around Falls Park, Sherman Park, and Veterans' Memorial Park. Create some family memories at Delbridge Museum of Natural History, Great Plains Zoo, and Thunder Road Family Fun Park while you're exploring the area around Sanford USD Medical Center.

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