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Check prices for these dates

Tonight
Mar 18 - Mar 19
Tomorrow
Mar 19 - Mar 20
This weekend
Mar 20 - Mar 22
Next weekend
Mar 27 - Mar 29

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Our top choices for Sanctuary hotels

Signature Cottage | Blackout drapes, iron/ironing board, free WiFi, bed sheets

The Anchor Inn

The Anchor Inn
2.0 star property
Mid Island, 12.8 km from Sanctuary
9.8 out of 10, Exceptional, (10 reviews)
"The property was beautiful, everything was in perfect condition, would definitely go back!!"
United States
Jennifer
The price is NT$11,187
NT$12,952 total
includes taxes & fees
Apr 14 - Apr 15
The Anchor Inn
Bay Inn Double Standard | Living area | Flat-screen TV

The Bay Inn at Lani Kai

The Bay Inn at Lani Kai
3.0 star property
21.8 km from Sanctuary
7.6 out of 10, Good, (377 reviews)
"Great and clean hotel friendly and family oriented! "
United States
Noel
The price is NT$5,430
NT$7,478 total
includes taxes & fees
Mar 24 - Mar 25
The Bay Inn at Lani Kai
BBQ/picnic area

Matlacha on Shoreview

Matlacha on Shoreview
2.0 star property
20.2 km from Sanctuary
9.6 out of 10, Exceptional, (241 reviews)
"Beautiful resort, great communication, super clean "
United States
Ronald
The price is NT$2,713
NT$5,161 total
includes taxes & fees
Apr 13 - Apr 14
Matlacha on Shoreview
Suite, 2 Bedrooms, Marina View | Egyptian cotton sheets, premium bedding, pillowtop beds, in-room safe

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
18.1 km from Sanctuary
9.0 out of 10, Wonderful, (1,000 reviews)
"Suite was clean… staff very friendly….food outstanding! We had a great week!"
United States
Shawn William
The price is NT$7,606
NT$9,757 total
includes taxes & fees
Apr 13 - Apr 14
The Westin Cape Coral Resort At Marina Village
Apartment (3 Bedrooms) | Interior

Canal-front Gem w/ Heated Pool in Cape Coral

Canal-front Gem w/ Heated Pool in Cape Coral
3.5 star property
20.7 km from Sanctuary
9.4 out of 10, Exceptional, (3 reviews)
"Excellent place ! the host was very kind ! for sure we will be back !"
United States
Edinaldo
The price is NT$4,086
NT$14,142 total
includes taxes & fees
Mar 24 - Mar 25
Canal-front Gem w/ Heated Pool in Cape Coral
Poolside bar

Dolphin Key Resort

Dolphin Key Resort
3.0 star property
23.8 km from Sanctuary
8.8 out of 10, Excellent, (1,236 reviews)
"good location"
United States
dan
The price is NT$3,192
NT$3,559 total
includes taxes & fees
Apr 1 - Apr 2
Dolphin Key Resort
Lobby

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
22.6 km from Sanctuary
8.8 out of 10, Excellent, (1,000 reviews)
"Room was clean and staff was fantastic "
United States
Wayne
The price is NT$3,652
NT$4,072 total
includes taxes & fees
Apr 5 - Apr 6
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
In-room safe, desk, laptop workspace, blackout drapes

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
23.9 km from Sanctuary
9.2 out of 10, Wonderful, (1,311 reviews)
"Great location, clean rooms, wonderful basic breakfast and coffee, I will be back again."
United States
Eduardo
The price is NT$3,236
NT$3,608 total
includes taxes & fees
Apr 5 - Apr 6
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Balcony view

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
2.5 star property
25.2 km from Sanctuary
5.8 out of 10, (1,001 reviews)
"It was perfect for my one night stay definitely will be coming back "
United States
Marice
The price is NT$3,578
NT$4,357 total
includes taxes & fees
Mar 19 - Mar 20
OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
Deluxe Studio Suite | Terrace/patio

White Orchid Apartments

White Orchid Apartments
2.0 star property
20 km from Sanctuary
8.4 out of 10, Very Good, (56 reviews)
"Clean, easy access, quiet, best bed and sheets ever!!!"
United States
Brooke
The price is NT$3,096
NT$4,484 total
includes taxes & fees
Mar 22 - Mar 23
White Orchid Apartments
Deluxe Suite (Second Floor Only) | Terrace/patio

Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort
2.5 star property
8.8 km from Sanctuary
9.6 out of 10, Exceptional, (154 reviews)
"Nice new rooms and great outdoor seating on the waterway, we saw lots of manatees "
United States
Ellen
The price is NT$5,051
NT$6,700 total
includes taxes & fees
Apr 1 - Apr 2
Off the Charts Inn & Out Island Resort
Classic Studio | Living area

Summerwind Studios

Summerwind Studios
2.0 star property
22.6 km from Sanctuary
8.2 out of 10, Very Good, (13 reviews)
"Very clean and roomy. Quiet neighborhood. Loves the shower; so relaxing. Only complaint is that we could have used some drinking glasses. I would stay here again. "
United States
Micki
The price is NT$2,852
NT$4,216 total
includes taxes & fees
Apr 7 - Apr 8
Summerwind Studios
Exterior

TriLuxe Inn & Studios

TriLuxe Inn & Studios
2.0 star property
22.7 km from Sanctuary
8.0 out of 10, Very Good, (20 reviews)
"We arrived after dark. And the neighborhood seemed sketchy."
United States
Laurie
The price is NT$2,147
NT$3,430 total
includes taxes & fees
Apr 6 - Apr 7
TriLuxe Inn & Studios
View from property

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
15.6 km from Sanctuary
8.4 out of 10, Very Good, (1,011 reviews)
"We've always loved staying here. "
United States
Ashley
The price is NT$11,140
NT$13,538 total
includes taxes & fees
Apr 6 - Apr 7
Marriott Sanibel Harbour Resort & Spa
Exterior

Candlewood Suites Fort Myers Sanibel Gateway by IHG

Candlewood Suites Fort Myers Sanibel Gateway by IHG
3.0 star property
25.4 km from Sanctuary
7.6 out of 10, Good, (1,000 reviews)
"The location was great for access to beaches"
United States
Shelly
The price is NT$2,969
NT$3,310 total
includes taxes & fees
Apr 7 - Apr 8
Candlewood Suites Fort Myers Sanibel Gateway by IHG
On the beach, sun loungers, beach towels

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 13.1 km from Sanctuary
9.2 out of 10, Wonderful, (1,684 reviews)
"Super nice pool and bar area and easy to get to the beach. Clean rooms and great location. "
United States
Marjorie
The price is NT$11,778
NT$13,931 total
includes taxes & fees
Apr 12 - Apr 13
Sanibel Island Beach Resort
Private beach nearby, motor boating, fishing

MALU LANI Inn & Marina

MALU LANI Inn & Marina
2.5 star property
24.7 km from Sanctuary
10.0 out of 10, Exceptional, (2 reviews)
"Clean Rooms, Beautiful Setting and lots of wildlife just outside the porch! We saw a Manatee, Dolphins, Alligator and plenty of Bird Life! The area is an excellent spot for biking and hiking! The Calusa Habitat Mounds are nearby and a friendly day hike! Also nearby is a Marina that takes you to an Island for lunch and hiking as well as visiting Islands in the area! Very relaxing and fun place to take the whole Family!"
United States
Mark Forrest
The price is NT$5,746
NT$9,920 total
includes taxes & fees
Apr 12 - Apr 13
MALU LANI Inn & Marina
Free daily buffet breakfast

Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
19.3 km from Sanctuary
8.8 out of 10, Excellent, (1,000 reviews)
"Everything was nice in room. & clean. Nice place to stay"
United States
Laura
The price is NT$5,075
NT$5,659 total
includes taxes & fees
Apr 9 - Apr 10
Residence Inn by Marriott Fort Myers Sanibel
Lobby lounge

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
3.0 star property
30.1 km from Sanctuary
8.6 out of 10, Excellent, (840 reviews)
"Just stayed one night. Room was clean, staff was helpful and polite. Did not swim but the pool looked great. Continental breakfast was actually good. "
United States
Angela
The price is NT$3,131
NT$3,491 total
includes taxes & fees
Apr 12 - Apr 13
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
Terrace/patio

Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers
3.0 star property
29.5 km from Sanctuary
8.8 out of 10, Excellent, (1,002 reviews)
"Great quick stay"
United States
Jason R
The price is NT$3,723
NT$4,151 total
includes taxes & fees
Mar 29 - Mar 30
Hilton Garden Inn Ft Myers
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Sanctuary

Find the best Sanctuary areas and neighborhoods for the activities you enjoy most.

Mid Island

While visiting Mid Island, you might make a stop by sights like Periwinkle Way and Sanibel Island Southern Beach.

West End

While visiting West End, you might make a stop by sights like J. N. Ding Darling National Wildlife Refuge and Bowman's Beach.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Periwinkle Way which includes cycling as well as an individual femail

Beachview Country Club Estates

If you're spending some time in Beachview Country Club Estates, Periwinkle Way and Sanibel Island Golf Club are top sights worth seeing.

Shell Harbor

Though Shell Harbor might not have many top sights, you can venture to the surrounding area to see attractions like Sanibel Moorings Botanical Gardens and Sanibel Sea School.

Top Sanctuary Hotel Reviews

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

6/10 Okay
"Tired hotel but extremely convenient and cheap for the area. We wanted to explore Sanibel and captiva again, but faced with £600 per night or the here for £200 per night. Fantastic launderette down the road and a Publix nearby for stocking your fridge as breakfast not so good. But overall compared to the island prices money well spent. "
David 2-night trip
Posted 4 hours ago
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

Frequently asked questions

What is Sanctuary like?
Travelers are sure to enjoy a stay in Sanibel's Sanctuary neighborhood. Consider a visit to J. N. Ding Darling National Wildlife Refuge as part of your Sanctuary travel plans.
How many hotels are there in the Sanctuary area?
With 10 Expedia hotels and other accommodations in Sanctuary to choose from, this is a good starting point for exploring the greater Sanibel area.
If I need to cancel my hotel reservation in Sanctuary, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to review top deals in Sanctuary.
Where can I learn more about changing or cancelling my trip to Sanctuary?
For more information about updating your trip to Sanctuary or cancelling it, click here.
What is there to do around this Sanibel neighborhood?
J. N. Ding Darling National Wildlife Refuge is an attraction you might want to check out while you're in Sanctuary. Castaways Marina and Blind Pass Beach are also worth a visit when you're out sightseeing in Sanibel.

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