San Francisco

Panama City

The Bridge of the Americas in summer, Panama City
The Bridge of the Americas in summer, Panama City
This great beach is not far from the Royal Decameron Panama - and it is usually deserted!
La entrada a la Ciudad de Panamá
Edificio el tornillo

Popular places to visit


San Francisco Hotel Deals

Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
The price is NT$4,248 per night from Apr 3 to Apr 4
NT$4,248
NT$4,673 total
Apr 3 - Apr 4
includes taxes & fees
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,006 reviews)
Clean and comfortable room. Bathroom needs an overall. Faucets are hard to open and close.

Reviewed on 2026/3/7

Sheraton Grand Panama
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
The price is NT$5,243 per night from Apr 1 to Apr 2
NT$5,243
NT$5,768 total
Apr 1 - Apr 2
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in ...
9/10 Wonderful! (1,011 reviews)
Great breakfast and staff. Pillow choice could be better, such as memory foam

Reviewed on 2026/3/6

Las Americas Golden Tower Panama
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica Panama City Panama
The price is NT$7,244 per night from Apr 5 to Apr 6
NT$7,244
NT$7,968 total
Apr 5 - Apr 6
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,003 reviews)
Highly recommended

Reviewed on 2026/3/3

JW Marriott Panama
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is NT$3,743 per night from Mar 28 to Mar 29
NT$3,743
NT$4,117 total
Mar 28 - Mar 29
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9/10 Wonderful! (1,013 reviews)
Great location and service.

Reviewed on 2026/3/4

Courtyard by Marriott Panama Multiplaza Mall
Aloft Panama

Aloft Panama

3.5 out of 5
Via Israel & Calle 76 Panama City Panama
The price is NT$3,764 per night from Mar 14 to Mar 15
NT$3,764
NT$4,140 total
Mar 14 - Mar 15
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a nightclub. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (975 reviews)
The hotel is nice only downside was they serve the same breakfast everyday

Reviewed on 2026/3/4

Aloft Panama
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,592 reviews)
Best few items: the AC worked extremely well, breakfast was good a few more hot items would have been nice. Coffee was excellent as well as the breakfast staff. Good location with the mall turning around and getting new life to it. All of the staff really tried hard to make you feel comfortable. ...

Reviewed on 2026/3/8

Decapolis Hotel Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around San Francisco

Aerial cityscape skyline of Panama City

Obarrio

Unique features of Obarrio include the casinos and coffeehouses. Make a stop by Calle 50 or Soho City Center while you're exploring the area.

Obarrio
Panama, Panama City

Punta Pacifica

Notable for its seaside views, restaurants, and casinos, Punta Pacifica is a sought-after destination for many travelers visiting Panama City. If you want to see some sights in the area, check out Avenida Balboa or Multiplaza Pacific Mall.

Punta Pacifica
 sunset sky above Panama City -  cityscape panorama view

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

Punta Paitilla
Summer time in Panama City, blue sky and sunny days to enjoy this city. #lifeatexpedia #PanamaCity #travel

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

Bella Vista
Aerial view of the city skyline of Panama City business district

Campo Alegre

If you're spending some time in Campo Alegre, Uruguay Street and Calle 50 are top sights worth seeing.

Campo Alegre
Old and traditional Yatch Club at Cinta Costera, Panama City, Panama.

Marbella

You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.

Marbella


San Francisco