San Francisco

Panama City

Photo by Hideki Yamagata
Photo by ‎James Barrow
Photo by Adrian Damian
Photo by Nóra Széll
Photo by Panama Roadrunner

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San Francisco Hotel Deals

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
Fully refundableReserve now, pay when you stay
The price is NT$4,718 per night from Feb 7 to Feb 8
NT$4,718
NT$5,190 total
Feb 7 - Feb 8
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,024 reviews)
Going location, great city views

Reviewed on 2026/1/4

Las Americas Golden Tower Panama
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla Panama City Panama
The price is NT$3,407 per night from Jan 24 to Jan 25
NT$3,407
NT$3,747 total
Jan 24 - Jan 25
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
9.2/10 Wonderful! (2,156 reviews)
Not enough pool loungers around pool, mismatched and many are broken! Visited the pool many times and not enough loungers for the number of guests!

Reviewed on 2026/1/13

Plaza Paitilla Inn Hotel
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4 out of 5
Via Israel y Calle 71, San Francisco Panama City Panama
The price is NT$3,487 per night from Feb 1 to Feb 2
NT$3,487
NT$3,836 total
Feb 1 - Feb 2
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,145 reviews)
We enjoyed the pool area, the free buffet style for breakfast with very attentive staff, parking was accessible and service at the front desk by Rafael & Carlos made our stay easy and enjoyable.

Reviewed on 2026/1/17

Ramada Plaza by Wyndham Panama Punta Pacifica
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica Panama City Panama
Fully refundableReserve now, pay when you stay
The price is NT$10,382 per night from Feb 7 to Feb 8
NT$10,382
NT$11,420 total
Feb 7 - Feb 8
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,004 reviews)
Clean room

Reviewed on 2026/1/8

JW Marriott Panama
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
The price is NT$4,077 per night from Jan 23 to Jan 24
NT$4,077
NT$4,485 total
Jan 23 - Jan 24
includes taxes & fees
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (1,005 reviews)
Great staff

Reviewed on 2026/1/15

Sheraton Grand Panama
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is NT$2,924 per night from Feb 6 to Feb 7
NT$2,924
NT$3,216 total
Feb 6 - Feb 7
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
8.8/10 Excellent! (1,002 reviews)
I will stay there again.

Reviewed on 2026/1/8

Courtyard by Marriott Panama Multiplaza Mall
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around San Francisco

Summer time in Panama City, blue sky and sunny days to enjoy this city. #lifeatexpedia #PanamaCity #travel

Obarrio

4/5(91 area reviews)

Unique features of Obarrio include the casinos and coffeehouses. Make a stop by Calle 50 or Soho City Center while you're exploring the area.

Obarrio
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Punta Pacifica

Notable for its seaside views, restaurants, and casinos, Punta Pacifica is a sought-after destination for many travelers visiting Panama City. If you want to see some sights in the area, check out Avenida Balboa or Multiplaza Pacific Mall.

Punta Pacifica
Hard Rock Hotel Panama #StunningStructures

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

Punta Paitilla
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Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Crown Casino. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

Bella Vista
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Pueblo Nuevo

While Pueblo Nuevo might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like El Dorado Mall and Multiplaza Pacific Mall.

Pueblo Nuevo
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Campo Alegre

4/5(368 area reviews)

If you're spending some time in Campo Alegre, Uruguay Street and Calle 50 are top sights worth seeing.

Campo Alegre


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