San Antonio Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to NT$5,067 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in San Antonio

Find the best San Antonio areas and neighborhoods for the activities you enjoy most. Learn more about San Antonio
La Merced Church which includes a city

Cusco Historic Center

7 out of top 10 points of interest in this area
4.5/5(904 area reviews)

Explore museums like Museo de Arte Precolombino and savor fusion and neo-Andean cuisine at local restaurants. Stroll through the artisan-filled San Blas neighborhood for a picturesque shopping experience.

Find hotels in Cusco Historic Center

San Antonio Hotel Deals

Wyndham Costa del Sol Cusco

Wyndham Costa del Sol Cusco

4 out of 5
Santa Teresa N 344 Cusco Cusco
Fully refundableReserve now, pay when you stay
The price is NT$3,122 per night from Feb 27 to Feb 28
NT$3,122
NT$3,434 total
Feb 27 - Feb 28
9.2/10 Wonderful! (1,158 reviews)
Clean cozy warm rooms. Layout of the hotel and breakfast was fantastic

Reviewed on 2026/2/9

Wyndham Costa del Sol Cusco
Palacio del Inka, A Luxury Collection Hotel by Marriott

Palacio del Inka, A Luxury Collection Hotel by Marriott

5 out of 5
Plazoleta Santo Domingo No 259 Cusco Cusco
Fully refundableReserve now, pay when you stay
The price is NT$9,523 per night from Feb 27 to Feb 28
NT$9,523
NT$11,775 total
Feb 27 - Feb 28
9.4/10 Exceptional! (984 reviews)
Staff is incredibly hospitable! They go above and beyond to make sure you enjoy your stay!

Reviewed on 2026/1/28

Palacio del Inka, A Luxury Collection Hotel by Marriott
Sonesta Hotel Cusco

Sonesta Hotel Cusco

4 out of 5
Ave. El Sol 954 Cusco Cusco
Fully refundableReserve now, pay when you stay
The price is NT$3,444 per night from Feb 23 to Feb 24
NT$3,444
NT$3,788 total
Feb 23 - Feb 24
9.6/10 Exceptional! (1,000 reviews)
Really enjoyed room. Breakfast was really good. Lots of options. Free shuttle to airport.

Reviewed on 2026/2/2

Sonesta Hotel Cusco
See all 1,696 properties in San Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a San Antonio vacation package cost?
We make it simple to travel the world, with San Antonio packages starting from as little as . You'll have the flexibility to combine your preferred hotels, airlines and car rental. For the ultimate escape, why not add a few activities and tours to your travel itinerary?
How do I get a cheap travel package to San Antonio?
Crafting your own San Antonio vacation package with Expedia is one of the easiest ways to save. We offer more than 550 partner airlines and 1,000,000 hotel options spread across the globe. With such a fabulous range to pick from, you'll have no trouble pulling together your perfect getaway.
Where should I stay in San Antonio?
With fascinating attractions such as Regional Hospital of Cusco and National University of Saint Anthony the Abbot in Cuzco in this neighborhood, see if you can find a hotel near either of them. Real Plaza Cusco is another sight that visitors flock to.
What are the top hotels in San Antonio?
If it's comfort and convenience you're seeking, you can't go past Apart Las Margaritas Hotel. Spend your nights relaxing here and your days roaming around San Antonio's best sights.
How far in advance should I book my San Antonio vacation?
While not all air carriers advertise tickets early, you can normally start comparing international fares on Expedia up to a year in advance. This is the time you'll bag some incredible deals. If you've left things to the last minute, you might get lucky. Low prices sometimes emerge a few weeks before departure.
What does an Expedia San Antonio travel package include?
With Expedia, you can choose a combination of car rentals, hotels and flights to build your perfect San Antonio package. Once you've made your booking, you can add on fun stuff like sightseeing tours and activities. Remember, the more you bundle, the bigger the savings!
What should I know before booking a San Antonio travel package?
Bundling your bookings into a San Antonio vacation package is the easiest way to organize your trip. Not only that, you'll save big just for combining your hotels, flights and car rentals. Once you've booked, why not add on an activity or a tour?
Can I choose my airline with a San Antonio Expedia vacation package?
You can, and with more than 550 airlines to select from throughout the world, you're not short on choice. Look through the available options and see which airline best fits your budget and needs.
If I'm not able to travel, can I cancel my San Antonio vacation package?
Plans can change unexpectedly, so yes, you can. You may be able to cancel or change your San Antonio vacation package at no cost within 24 hours of booking. For older bookings, you can still cancel and rebook, but your car rental company, hotel or airline may charge a fee. Looking for more information? Check out our Customer Service Portal. We're here to help make sure your trip goes off without a hitch.

Discover the most popular places to visit in San Antonio

Plaza de Armas featuring a garden and a church or cathedral

Plaza de Armas

4.5/5(853 reviews)

Cusco’s busy main square has been the center of public life for centuries. Enjoy its spacious layout, ancient churches and restaurants.

Plaza de Armas
Cusco San Pedro Market showing markets and food as well as a small group of people

San Pedro Market

4.5/5(451 reviews)

Get caught up in the chaos of this intriguing attraction and enjoy a uniquely Andean experience.

San Pedro Market
1_1eade4e2-e237-462e-beff-16f58653d560_raw

Cusco Cathedral

4.5/5(551 reviews)

An imposing building constructed with stones from an Inca fortress is celebrated for its beautiful architecture and artwork that spans three centuries.

Cusco Cathedral
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.