Grand Isle, FL

Port St. Joe

A sunset over a body of water with a bridge in the background.

Grand Isle Hotel Deals

Comfort Suites

Comfort Suites

2.5 out of 5
264 N Tyndall Pkwy Panama City FL
The price is NT$2,537 per night from Nov 30 to Dec 1
NT$2,537
NT$2,741 total
Nov 30 - Dec 1
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Comfort Suites
MainStay Suites Port Saint Joe South

MainStay Suites Port Saint Joe South

2.5 out of 5
3951 E Highway 98 Port St. Joe FL
The price is NT$3,678 per night from Dec 6 to Dec 7
NT$3,678
NT$4,119 total
Dec 6 - Dec 7
includes taxes & fees
Book a stay at this business-friendly hotel in Port St. Joe. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (793 reviews)
"Pros: Very attentive and friendly staff! Towels and bedding were very clean. Cons: The building and facilities appeared to be poorly maintained. Very moldy and musty smelling in the entire building and especially the room. The bathroom door was filthy and mold growing around shower enclosure. It ..."

Reviewed on 2026/11/8

MainStay Suites Port Saint Joe South
Extended Stay America Select Suites - Panama City - Callaway

Extended Stay America Select Suites - Panama City - Callaway

2.5 out of 5
902 N Tyndall Parkway Panama City FL
The price is NT$2,097 per night from Dec 7 to Dec 8
NT$2,097
NT$2,266 total
Dec 7 - Dec 8
includes taxes & fees
Stay at this hotel in Panama City. Enjoy free WiFi, free parking, and laundry facilities. Popular attractions Veterans Park and Skater's Choice are located ...
Extended Stay America Select Suites - Panama City - Callaway
The Port Inn - Port St Joe, an Ascend Collection Hotel

The Port Inn - Port St Joe, an Ascend Collection Hotel

3.5 out of 5
501 Monument Ave. Port St. Joe FL
The price is NT$4,304 per night from Nov 22 to Nov 23
NT$4,304
NT$4,820 total
Nov 22 - Nov 23
includes taxes & fees
Stay at this hotel in Port St. Joe. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
The Port Inn - Port St Joe, an Ascend Collection Hotel
Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

2.5 out of 5
5627 E Highway 22 State Route Panama City FL
The price is NT$2,760 per night from Dec 6 to Dec 7
NT$2,760
NT$2,982 total
Dec 6 - Dec 7
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG
Driftwood Inn

Driftwood Inn

2 out of 5
2105 U.S. 98 Mexico Beach FL
The price is NT$5,893 per night from Dec 7 to Dec 8
NT$5,893
NT$6,601 total
Dec 7 - Dec 8
includes taxes & fees
Book a stay at this beach hotel in Port St. Joe. Enjoy free WiFi, free parking, and a beach locale. Popular attractions Mexico Beach Park and Mexico Beach are ...
9.6/10 Exceptional! (137 reviews)
"Right on the beach"

Reviewed on 2026/11/6

Driftwood Inn
See all 2,275 properties in Grand Isle
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Grand Isle

Find the best Grand Isle areas and neighborhoods for the activities you enjoy most.
A marina at sunset with boats docked and a wooden pier.
Photo by Russell Hewatt
Open Photo by Russell Hewatt

Downtown Port St. Joe

While visiting Downtown Port St. Joe, you might make a stop by sights like Port Saint Joe City Hall and Constitution Convention Museum State Park.

A white house with a black roof, a white lighthouse with a black top, and a calm lake with purple flowers in the foreground.

Cape Breezes

While Cape Breezes isn't home to many top sights, T.H. Stone Memorial St. Joseph Peninsula State Park and St. Joseph Peninsula State Park are some notable places to visit nearby.

A beach with driftwood formations at sunset.

Gulf Aire

While Gulf Aire isn't home to many top sights, Saint Joe Beach and Mexico Beach are some notable places to visit nearby.

A sandy beach with calm waters and a large cloud in the sky.

Waterside Village

Though Waterside Village might not have many top sights, you can venture to the surrounding area to see attractions like Mexico Beach Marina and Mexico Beach.

A coastal landscape with tall grasses, a palm tree, and a sunset over the water.

Palms

While there might not be top attractions in Palms, you can explore the larger area and discover places like Mexico Beach and Mexico Beach Marina.

Grand Isle, FL