Photo by Bill Dillard

Poplar Bluff Vacation Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Nov 20 - Nov 22
In two months
Jan 1 - Jan 3
In three months
Jan 29 - Jan 31
In four months
Feb 26 - Feb 28

Our top choices for Poplar Bluff vacation rentals

A rustic cabin with a metal roof, surrounded by a wooden deck and picnic tables, set in a forested area.

1. Lake Wappapello

Lake Wappapello
2.0 star property
Williamsville
8.4 out of 10, Very good, (7 reviews)
"Pet friendly. Family-friendly "
United States
Tonya
The price is NT$2,932
NT$3,093 total
includes taxes & fees
Nov 5 - Nov 6
Lake Wappapello
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Find vacation rentals that suit your style

cabin image
Cabins
Cabins
Apartment image
Apartments
Apartments

Top Poplar Bluff Hotel Reviews

A spacious lobby with a reception desk, seating area, and large windows.
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
Poplar Bluff

10/10 Excellent

Everything was absolutely great will recommend to all my family and friends.
United States
Irena
Reviewed October 30, 2026
Drury Inn & Suites Poplar Bluff

Find out more about Poplar Bluff

Search for holiday rentals in Poplar Bluff on Expedia! You can easily find your home rentals, villas, holiday apartments in Poplar Bluff using one of the methods below:

  • View our selection of featured holiday rentals in Poplar Bluff
  • Use the map to find apartments and other holiday homes in the Poplar Bluff neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Poplar Bluff while they last

Look no further and take a look at our great range of rental properties in Poplar Bluff!

Frequently Asked Questions

Can I find a vacation rental in Poplar Bluff?

Yes, we offer vacation rentals in Poplar Bluff near Mo-Ark Regional Railroad Museum, or you can select a secluded option if you want a relaxing stay. Our travelers say Poplar Bluff has a good selection of restaurants. Make sure you have time to check out the water park and waterfalls during your trip.

How many vacation rentals are there in Poplar Bluff?

Choose from 6 Expedia vacation rentals in Poplar Bluff for a memorable vacation.

What can I see and do in Poplar Bluff?

Cultural attractions include Mo-Ark Regional Railroad Museum and Margaret Harwell Art Museum, whereas Mark Twain National Forest is one spot to enjoy nature. Other places in town to visit include Black River Coliseum and North Main Street Historic District.

What are vacation rentals like in Poplar Bluff?

Vacation rentals are private properties you can book for a short or long stay in Poplar Bluff. Vacation rentals offer extras like laundry facilities and kitchens so you'll be comfy for your stay. If you're concerned about cleanliness, vacation rentals can provide a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you to travel. You'll also get more space in a vacation rental than in a hotel, which is another reason why a vacation rental is an attractive choice for family gatherings.