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Our top choices for Panhandle Plains hotels

A multi-story hotel with a stone facade, large windows, and a covered outdoor seating area.

1. Residence Inn by Marriott Wichita Falls

Wichita Falls

Anthony

NT$6,725 total

includes taxes & fees

Oct 30 - Oct 31

A La Quinta hotel with a modern design, featuring a prominent sun motif on the facade, multiple floors, and a covered entrance area.

2. La Quinta Inn & Suites by Wyndham Sweetwater East

Sweetwater

Keith

NT$7,308 total

includes taxes & fees

Oct 31 - Nov 1

A hotel reception area with a wooden reception desk, a black doormat with the hotel name, and a modern interior design.

3. Fairfield Inn & Suites by Marriott Wichita Falls Northwest

Wichita Falls

Ludmila

NT$4,584 total

includes taxes & fees

Nov 22 - Nov 23

A modern room with a sofa, a chair, a lamp, and a television.

4. Holiday Inn Express & Suites Amarillo West by IHG

Amarillo

Marie-Pascale

NT$4,310 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a bed, two bedside tables, a chair, and a lamp.

5. Sleep Inn & Suites Shamrock

Shamrock

Kenneth

NT$3,401 total

includes taxes & fees

Nov 26 - Nov 27

An outdoor patio with a stone wall, a fire feature, and seating.

6. Hampton Inn & Suites Canyon

Canyon

Pam

NT$4,695 total

includes taxes & fees

Nov 21 - Nov 22

A multi-story hotel with a modern design, featuring a prominent entrance with glass doors and a covered area.

7. Best Western Plus Amarillo East Hotel

Amarillo

Judy

NT$4,109 total

includes taxes & fees

Nov 4 - Nov 5

A modern lounge area with seating, tables, and a kitchen area.

8. Tru By Hilton Amarillo West

Amarillo

NANCY

NT$3,787 total

includes taxes & fees

Nov 4 - Nov 5

A spacious restaurant with high ceilings, stone walls, and large windows.

9. Drury Inn & Suites Amarillo

Amarillo

sarah

NT$4,047 total

includes taxes & fees

Nov 8 - Nov 9

10. Embassy Suites by Hilton Amarillo Downtown

Downtown Amarillo

Heather

NT$4,837 total

includes taxes & fees

Nov 22 - Nov 23

A hotel entrance with a stone facade, a glass door entrance, and a tiled floor.

11. Microtel Inn & Suites by Wyndham Sweetwater

Sweetwater

barbara

NT$4,532 total

includes taxes & fees

Nov 1 - Nov 2

A spacious lobby with a reception desk, seating area, and a patterned wall mural.

12. La Quinta Inn & Suites by Wyndham Amarillo Airport

Amarillo

Zane

NT$5,606 total

includes taxes & fees

Nov 26 - Nov 27

13. Home2 Suites by Hilton Wichita Falls, TX

Wichita Falls

hai

NT$6,295 total

includes taxes & fees

Oct 30 - Oct 31

A modern hotel with a prominent Tru by Hilton sign, multiple parking spaces, and a well-lit entrance area.

14. Tru by Hilton Wichita Falls, TX

Wichita Falls

Darlys

NT$5,166 total

includes taxes & fees

Nov 8 - Nov 9

A modern reception area with a desk, seating, and a large wall art piece.

15. City Express by Marriott Amarillo Northwest

Amarillo

Janet

NT$3,822 total

includes taxes & fees

Nov 10 - Nov 11

An outdoor seating area with blue sofas, orange chairs, and a central fire feature.

16. Hampton Inn & Suites Dalhart

Dalhart

James

NT$4,726 total

includes taxes & fees

Nov 8 - Nov 9

A spacious lobby with a modern design, featuring a seating area with colorful cushions, a large chandelier, and a flat-screen TV mounted on the wall.

17. Best Western Plus Medical Center

Amarillo

Naga Raghuveer

NT$3,791 total

includes taxes & fees

Nov 1 - Nov 2

A Country Inn with a red and white color scheme, a reception desk, a coffee bar, and a large window with blinds.

18. Route 66 Desert Rose Country Inn

Vega

Marquitta

NT$2,510 total

includes taxes & fees

Nov 10 - Nov 11

An indoor swimming pool with a diving board, seating area, and arched windows.

19. Spark by Hilton Dumas

Dumas

Manuel

NT$2,942 total

includes taxes & fees

Nov 25 - Nov 26

An outdoor seating area with a fire pit, lounge chairs, and a building with large windows and a covered patio.

20. TownePlace Suites by Marriott Amarillo West/Medical Center

Amarillo

Mitchell

NT$5,059 total

includes taxes & fees

Nov 1 - Nov 2

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Vacation Rentals in Panhandle Plains

Aparthotel

A cozy living room with a brown leather sofa, wooden flooring, a kitchen area with a microwave and refrigerator, and a doorway leading to a bedroom.

Life's Suites

Hamlin

"I very much enjoyed my stay here. Loved the room and would absolutely stay again."

Aparthotel

A modern bar area with a wooden bar, stools, and a sofa.

Town Place Studio Extended Stay Snyder, TX

Snyder

"Nice place "

Cottage

A modern kitchen with white cabinets, granite countertops, stainless steel appliances, and a wooden ceiling.

Pet-friendly Texas Home w/ Furnished Patio & Grill

Graford

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Stay near popular Panhandle Plains attractions

A large building with a tower and arched entrance.

Texas Tech University

9.4/10 (2,810 reviews)

Explore the campus of Texas Tech University, a top college in Lubbock. You can attend a sporting event while in the area.

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Learn more about Panhandle Plains

Big skies, big landscapes and a big welcome await in the northernmost region of Texas, a place characterized by its stunning frontier wilderness.

See all hotels in Panhandle Plains

A row of colorful, graffiti-covered benches in a desert setting.

Top Panhandle Plains Hotel Reviews

Holiday Inn Express & Suites Amarillo West by IHG

10/10 Excellent

"Everything I would expect!"

The Cactus Cove Inn and Suites

8/10 Good

"The amenities here were amazing. The entire center of the hotel was full of things to do from small children to adults. The staff were amazingly helpful. The breakfast area is beautiful and full of options. The food was delicious. I traveled for business but this is definitely a place that I will be bring my family back to."