The Best Hotels Closest to North Mississippi Medical Center in Tupelo for 2026

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Our top choices for North Mississippi Medical Center hotels

A modern lounge area with a neon sign, large windows, and a pool table.

A bar area with a large screen, bar stools, and a variety of bottles.

A modern living room with a blue sofa, a round coffee table, and a cityscape view through large windows.

A modern hotel with a brick facade, large windows, and a covered outdoor seating area.

1. Hotel Tupelo, a Wyndham Hotel

2.2 km from North Mississippi Medical Center

Jason

NT$5,026

NT$5,491 total

includes taxes & fees

Sep 13 - Sep 14

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A fitness center with treadmills, elliptical machines, and exercise balls.

A laundry area with two Whirlpool front-loading washers, a Tide detergent dispenser, and a sign indicating it's for guest use only.

2. Holiday Inn Hotel & Suites Tupelo North by IHG

3 km from North Mississippi Medical Center

Larry

NT$3,849

NT$4,205 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with a conference table, chairs, a bed, a TV, and a door leading to another room.

A multi-story hotel with a covered outdoor seating area, a paved walkway, and a landscaped garden.

A hotel room with a dark wood dining table, a brown leather chair, a microwave, a refrigerator, and a corkboard on the wall.

A hotel fitness center with treadmills, a stationary bike, and weight machines.

3. Candlewood Suites Tupelo North by IHG

3 km from North Mississippi Medical Center

Rhonda

NT$3,849

NT$4,205 total

includes taxes & fees

Sep 20 - Sep 21

A hotel entrance with a covered waiting area, a bench, and a car parking lot.

A reception desk with a laptop, a large decorative letter 'H', and a colorful striped wall in the background.

A hotel room with two beds, each with a patterned bedspread, a bedside table with a clock, and a wall-mounted light fixture.

A staircase with carpeted steps and a black handrail, leading to a hallway with wooden walls and a tiled floor.

4. Studio 6 Suites Tupelo, MS - North

3.1 km from North Mississippi Medical Center

David

NT$1,819

NT$2,144 total

includes taxes & fees

Sep 21 - Sep 22

A reception area with a wooden desk, a reception counter, a waiting area with brown upholstered chairs, a large window with a view of buildings, and a door marked "EXIT".

A hotel room with a green sofa, a desk with a computer and lamp, a small refrigerator, and a round mirror on the wall.

A compact kitchen with wooden cabinets, a microwave, a toaster, and a juice dispenser. There are two red chairs and a wooden table.

A hotel room with a desk, chair, television, minibar, and a bed.

5. SureStay Hotel by Best Western Tupelo North

2.8 km from North Mississippi Medical Center

James

NT$1,846

NT$2,017 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with a bed, a desk with a flat-screen TV, a microwave, a sink, and a mirror.

A modern kitchen with a built-in stove, a coffee machine, and a refrigerator.

A hotel lobby with a red chair, a table with stacked items, and a large window offering a view of the parking lot and trees.

A reception area with a counter, a red chair, a small table with a lamp, and a view of the parking lot outside.

6. Motel 6 Tupelo, MS - Downtown

3 km from North Mississippi Medical Center

kerri

NT$1,590

NT$1,737 total

includes taxes & fees

Sep 16 - Sep 17

A room with a green wall, a decorative wall piece, an air conditioner, and a welcome sign.

A hotel room with two beds, a nightstand, a lamp, and two framed pictures on the wall.

A sign for Scottish Inns with a clear sky in the background.

7. Scottish Inns

2 km from North Mississippi Medical Center

David

NT$1,893

NT$2,068 total

includes taxes & fees

Sep 13 - Sep 14

A hotel room with two beds, a desk, a chair, a television, and a window.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a counter.

A hotel fitness center with multiple treadmills, ellipticals, and a mirrored wall.

A hotel lobby with a chandelier, leather chairs, a fireplace, and a television.

8. Holiday Inn Express Hotel & Suites Tupelo by IHG

4.1 km from North Mississippi Medical Center

Fernando

NT$3,250

NT$3,550 total

includes taxes & fees

Oct 11 - Oct 12

A modern hotel lobby with a reception desk, seating area, and unique lighting fixtures.

A modern hotel building with a prominent 'tru by Hilton' sign, multiple windows, and a well-lit entrance.

A modern lounge area with a blue sofa, grey armchairs, and a hanging chair.

A breakfast buffet area with various food items and a coffee machine.

9. Tru By Hilton Tupelo

4.3 km from North Mississippi Medical Center

Steven

NT$3,079

NT$3,363 total

includes taxes & fees

Sep 27 - Sep 28

A multi-story hotel with a prominent entrance, a covered patio area, and a landscaped courtyard.

A spacious lobby with patterned seating, a stone accent wall, a flat-screen TV, and a snack bar.

A rectangular swimming pool with a tiled deck, surrounded by a brick wall and metal fencing.

A hotel room with a large bed, a desk, a chair, a TV, and a window with patterned curtains.

10. La Quinta Inn & Suites by Wyndham Tupelo

3.6 km from North Mississippi Medical Center

Teresa

NT$3,066

NT$3,350 total

includes taxes & fees

Sep 14 - Sep 15

A modern, well-lit office space with multiple tables and chairs, a reception area, and large windows offering a view of greenery.

A modern lobby with a reception desk, yellow chairs, a round table, and a large window.

A modern building with large windows and a patio area with white metal furniture.

A hotel with a modern facade, a covered entrance, and a well-maintained lawn.

11. Spark by Hilton Tupelo

6.3 km from North Mississippi Medical Center

Melissa

NT$3,105

NT$3,392 total

includes taxes & fees

Sep 21 - Sep 22

A hotel lobby with a reception desk, seating area with ottomans, and a patterned carpet.

An indoor swimming pool with a clear view of the pool area, including the poolside seating and the pool's edge.

A kitchen with granite countertops, wooden cabinets, and a tiled backsplash.

A multi-story hotel with a covered entrance and a parking area.

12. Best Western Plus Tupelo Inn & Suites

6.3 km from North Mississippi Medical Center

Vinson

NT$3,129

NT$3,418 total

includes taxes & fees

Sep 13 - Sep 14

A spacious hotel lobby with a dining area, sofas, and a TV mounted on the wall.

A hotel room with a wooden desk, a blue sofa, a small ottoman, a chair, a lamp, and framed pictures on the wall.

A reception area with a stone wall, wooden reception desk, and a vending machine.

A hotel room with a bed, a desk, a chair, a sofa, a TV, and a lamp.

13. Comfort Suites North Tupelo

6.8 km from North Mississippi Medical Center

Peggy

NT$3,281

NT$3,585 total

includes taxes & fees

Oct 4 - Oct 5

An outdoor seating area with chairs and a fire pit, a brick building, and a clear sky.

A modern lounge area with a green sofa, red chairs, and a wooden table.

An indoor swimming pool with clear blue water, surrounded by yellow and blue chairs, and a water fountain on the left.

A gym with exercise equipment, a spinning bike, and a bench.

14. Home2 Suites By Hilton Tupelo, Ms

4.3 km from North Mississippi Medical Center

Katy

NT$3,630

NT$3,965 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with a bed, a TV mounted on the wall, a desk with a chair, a small refrigerator, and a bedside table.

A Red Roof Inn sign on a stone wall, a vase with flowers on a table, and two leather chairs.

A Red Roof Inn with a clear sky, a parking lot, and a well-maintained lawn.

15. Red Roof Inn Tupelo

3.6 km from North Mississippi Medical Center

Harley

NT$1,948

NT$2,128 total

includes taxes & fees

Sep 20 - Sep 21

A reception area with a stone wall, a painting of autumn trees, and a potted plant.

A hotel room with a bed, two bedside tables with lamps, a sofa, and a small table.

A living room with a sofa, chairs, a coffee table, a flat-screen TV, a ceiling fan, and artwork on the walls.

A hotel with a red roof and a sign indicating it is an Americor Best Value Inn.

16. Americas Best Value Inn Tupelo Barnes Crossing

7.9 km from North Mississippi Medical Center

John

NT$2,051

NT$2,377 total

includes taxes & fees

Sep 13 - Sep 14

A gym with treadmills, elliptical machines, and free weights.

A hotel room with a sofa, armchair, table, lamp, TV, and a map on the wall.

A swimming pool with a metal ladder, surrounded by a brick wall and stone tiles.

17. Comfort Inn Tupelo Central

3.6 km from North Mississippi Medical Center

Riesha

NT$2,800

NT$3,059 total

includes taxes & fees

Oct 11 - Oct 12

A Courtyard Marriott hotel entrance at night with a well-lit facade, a covered parking area, and a landscaped garden.

A modern lobby with a reception desk, seating area, and a large abstract mural.

A modern hotel lobby with round tables, comfortable seating, a bar area, and a TV screen displaying golf.

A hotel room with a bed, a sofa, a desk, and a TV.

18. Courtyard By Marriott Tupelo

3.9 km from North Mississippi Medical Center

Keyunna

NT$3,663

NT$4,002 total

includes taxes & fees

Oct 4 - Oct 5

A buffet area with various food options, a coffee machine, and a refrigerator.

A hotel reception area with a reception desk, a waiting area with leather couches, and artwork on the walls.

A gym with exercise equipment, a water dispenser, and a clock on the wall.

A business center with a computer station, a black leather chair, and a reception desk with a lamp.

19. Quality Inn Tupelo Central

4 km from North Mississippi Medical Center

Mary Ann

NT$2,089

NT$2,282 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with a large bed, a wooden ceiling, a TV, a desk, and a bathroom visible in the background.

A hotel room with a wooden floor, a desk with a chair, a sofa, a TV, a mini-fridge, and a sliding door leading to a balcony.

A reception area with a blue curtain backdrop, a reception desk, and a sign that reads "Baymont Inn & Suites."

A wooden deck with chairs overlooking a pool area.

20. Baymont by Wyndham Tupelo

4.2 km from North Mississippi Medical Center

Sammy

NT$2,253

NT$2,461 total

includes taxes & fees

Oct 5 - Oct 6

View all properties

Compare popular hotels close to North Mississippi Medical Center

Property	Property class	Guest rating
Hotel Tupelo, a Wyndham Hotel	9.6 Exceptional 695 reviews	View
Holiday Inn Hotel & Suites Tupelo North by IHG	9.2 Wonderful 1,000 reviews	View
Candlewood Suites Tupelo North by IHG	8.6 Excellent 463 reviews	View
Studio 6 Suites Tupelo, MS - North	7.2 Good 607 reviews	View
SureStay Hotel by Best Western Tupelo North	7.4 Good 254 reviews	View

Top North Mississippi Medical Center Hotel Reviews

Comfort Inn Tupelo Central

10/10 Excellent

"Everything was great, wll stay again. Highly recommend..."

Red Roof Inn Tupelo

10/10 Excellent

"I booked and paid for the room on the Hotels.com app, got the $9 room protection just in case something happed and check in was very fast and easy. Amazing price for a remarkable experience. The room was very nice and clean. The water pressure was amazing and the air conditioner was working overtime. The front desk lady answered very quickly and was so nice when I called to see what time the pool closed, which was both refreshing and relaxing. I had an amazing time with my family and I can’t wait for my next stay!"

Hotel Tupelo, a Wyndham Hotel

10/10 Excellent

"Superb boutique hotel. Thank you for a perfect stay."

Holiday Inn Express Hotel & Suites Tupelo by IHG

10/10 Excellent

"One night stay, room was clean spacious and comfortable, good breakfast, nearby local restaurants. Everything you need for an overnight stop."

Spark by Hilton Tupelo

8/10 Good

"all good"

Courtyard By Marriott Tupelo

10/10 Excellent

"Clean, convenient easy parking"

Holiday Inn Hotel & Suites Tupelo North by IHG

10/10 Excellent

"Love the hotel, but hate the breakfast wasn't included."

Scottish Inns

10/10 Excellent

"I try to matain a place of higher accomplishing in my living area when I do clean my room. Here at the Scottish the cleaning lady who make sure you have clean sheets do their job to the max."

Frequently asked questions

What's the area like around North Mississippi Medical Center?

North Mississippi Medical Center is located in a welcoming area of Tupelo known for its major shopping area. If you're looking for a convenient place to stay, check out the 7 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to North Mississippi Medical Center?

Best Western Plus Tupelo Inn & Suites is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 3.9 mi (6.3 km) from North Mississippi Medical Center. Other good options within a few miles include Baymont by Wyndham Tupelo and Holiday Inn Hotel & Suites Tupelo North by IHG.

How many hotels are there near North Mississippi Medical Center?

Expedia has 7 hotels and other accommodations within a mile from North Mississippi Medical Center.

If I need to cancel the hotel reservation for my stay near North Mississippi Medical Center, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best options available near North Mississippi Medical Center.

Where can I learn more about changing or cancelling my trip in the area near North Mississippi Medical Center?

For more information about rescheduling or cancelling your stay near North Mississippi Medical Center, click here.

What can I see and do near North Mississippi Medical Center?

You'll want to browse the exhibits at Elvis Presley Center and Oren Dunn City Museum. You might spend a leisurely day outdoors at Ballard Park and Elvis Presley Lake and Campground. Stopping by Cadence Bank Arena, Rob Leake City Park Tennis Center, or Cinemark Tupelo Movies 8 is a fun way to see all the area has to offer.

Find hotels near North Mississippi Medical Center, Tupelo from NT$1,737

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for North Mississippi Medical Center hotels

1. Hotel Tupelo, a Wyndham Hotel

2. Holiday Inn Hotel & Suites Tupelo North by IHG

3. Candlewood Suites Tupelo North by IHG

4. Studio 6 Suites Tupelo, MS - North

5. SureStay Hotel by Best Western Tupelo North

6. Motel 6 Tupelo, MS - Downtown

7. Scottish Inns

8. Holiday Inn Express Hotel & Suites Tupelo by IHG

9. Tru By Hilton Tupelo

10. La Quinta Inn & Suites by Wyndham Tupelo

11. Spark by Hilton Tupelo

12. Best Western Plus Tupelo Inn & Suites

13. Comfort Suites North Tupelo

14. Home2 Suites By Hilton Tupelo, Ms

15. Red Roof Inn Tupelo

16. Americas Best Value Inn Tupelo Barnes Crossing

17. Comfort Inn Tupelo Central

18. Courtyard By Marriott Tupelo

19. Quality Inn Tupelo Central

20. Baymont by Wyndham Tupelo

Compare popular hotels close to North Mississippi Medical Center

Top North Mississippi Medical Center Hotel Reviews

Comfort Inn Tupelo Central

Red Roof Inn Tupelo

Hotel Tupelo, a Wyndham Hotel

Holiday Inn Express Hotel & Suites Tupelo by IHG

Spark by Hilton Tupelo

Courtyard By Marriott Tupelo

Holiday Inn Hotel & Suites Tupelo North by IHG

Scottish Inns

Frequently asked questions

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