Mytilene Vacations

Book a Hotel + Flight or Car together to unlock savings

Photo by Jadranka Džepina
    deals illustration
    Better together
    Save up to NT$5,067 when you book a flight and hotel together*
    stays illustration
    Find the right fit
    With over 300,000 hotels worldwide, it's easy to create a perfect package
    luggage illustration
    Rest easy
    Plan, book, and manage your trip all in one place

Find the Best Mytilene Vacation Packages

Mytilene Beach Vacation

Get set to live out those beachy daydreams on your upcoming Mytilene vacation. Set off on a lovely stroll, take in the sweeping ocean views and collect unique seashells during your trip to Mytilene. Located just 10 kilometers from the city center, Thermi Beach is the place to be for many travelers. Look through our Mytilene packages and watch your travel budget stretch further!

Things You Should Know About Mytilene

  • If you want that beachside lifestyle, have a look at our Mytilene beach hotels. Beautiful water views and refreshing sea air — what more could anyone want?
  • Take a look at Sunrise Resort Hotel and Elysion Hotel. These hotels might just be perfect for your vacation in Mytilene.
  • There are plenty of activities that keep the 28,300 or so residents of Mytilene busy. A quick look at our Mytilene things to do page will let you in on everything this place has to offer.
  • If you're searching for things to do while you're in town, add University of the Aegean, Thermi Beach and Port of Mytilene to your travel schedule. Also, take a look at our Mytilene vacation deals to save money on your experiences, hotels and more.

Mytilene Hotel Deals

Heliotrope Hotels
Heliotrope Hotels
4 out of 5
Varia, Mytilene, Lesvos, Lesvos Island
The price is NT$4,282 per night from Jul 6 to Jul 7
NT$4,282
NT$5,032 total
Jul 6 - Jul 7
includes taxes & fees
8.4/10 Very Good! (179 reviews)
"I LOVE the staff here. They are consistently friendly and helpful. The pool was being worked on and that was a bummer."

Reviewed on 2025/6/6

Heliotrope Hotels
Theofilos Paradise Boutique Hotel
Theofilos Paradise Boutique Hotel
4 out of 5
7, Skra str, Hatzidimitriou Park, Mytilene, Lesvos
9.6/10 Exceptional! (143 reviews)
"Our fourth time at this hotel - everything was great."

Reviewed on 2025/6/13

Get rates
Theofilos Paradise Boutique Hotel
Mythical Coast Wellness Retreat
Mythical Coast Wellness Retreat
5 out of 5
Agrilia, Lesvos
8.6/10 Excellent! (27 reviews)
"Great property with lovely views and friendly staff. Only issue is that the upper floors of some buildings are not handicapped accessible and you will have to carry luggage’s up the stairs. To avoid stay on one of the main buildings"

Reviewed on 2024/8/2

Get rates
Mythical Coast Wellness Retreat
See all 163 properties in Mytilene
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mytilene vacation package cost?
You can grab a vacation package to this top destination on Expedia. But how much your vacation to Mytilene costs will depend on the season, length of stay and hotel choice.
What are the cheapest months to go to Mytilene?
If you're hoping to score a cheap Mytilene vacation package, consider visiting in February, March and December. You're likely to find lower prices on flights and accommodations during these months --- ideal for budget-conscious travelers.
How many days is enough for Mytilene?
With a well-organized schedule, you can easily tick off the main Mytilene attractions in a few days. But if you'd like to discover lesser-known spots or go on day trips, think about booking your Mytilene vacation for longer.
Is it worth booking a vacation package to Mytilene?
Well known for its history, festivals and family-friendly attractions, a Mytilene vacation is a hit with all types of travelers. Be sure to check out top sights like Olive-press Museum of Archipelagos Society and Temple of Messon, and consider renting a set of wheels for day trips to discover even more.
How to find the best Mytilene package deals?
Use Expedia's handy filters to help you find some fabulous Mytilene package deals. When you start your search, just set your maximum budget and then order the results by "Price: low to high." If you want to save, plan your trip for midweek, or browse for Mytilene package deals in the off-season. Play around with your travel dates and you may score even better discounts. As a rule of thumb, it's usually best to book your vacation package well in advance.
Is it cheaper to book a Mytilene vacation as a package?
An Expedia vacation package could land you great savings when compared to booking stays and flights separately. Better still, you can personalize your Mytilene escape to match your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Check out our great deals to see how much you can save.
When to book a vacation package to Mytilene?
Land incredible discounts by reserving your flights ahead of time with Expedia. If being spontaneous is more your thing, snap up one of our last-minute deals for an impromptu Mytilene escape.
How to plan a trip to Mytilene?

  1. Pick your dates: The things you want to do in Mytilene and your preferred season can help you decide when to go.
  2. Set your budget: Factor in costs such as flights, food and transportation when calculating how much to save for your trip to Mytilene. Then, choose a hotel that suits your budget, whether that's a wallet-friendly stay or a high-end getaway.
  3. Decide your trip length: Think about how much time you'd like to spend discovering Mytilene. Plan your itinerary so you can get to all the experiences and attractions you're interested in at a leisurely pace.
  4. Bundle your bookings: With your travel dates in place, you can combine your flights, car rental, hotels and more into a customized Mytilene vacation package.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.