Bridge over Mississippi River, New Orleans in background

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Our top choices for Mississippi River hotels

River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
9.0 out of 10, Wonderful, (367 reviews)
"Hotel was in a great location overlooking the Mississippi River and right next to the bridge entrance. Parking lot was tight for larger vehicles and not trailer friendly but the staff was wonderful! This hotel worked out great for our 2 night stay. Thank you!!"
United States
Michael
The price is NT$2,524
NT$2,866 total
includes taxes & fees
Jun 25 - Jun 26
River's Edge Motel

The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.4 out of 10, Exceptional, (25 reviews)
"Very nice place to stay loved the brick walls and wood floors leading up to the rooms"
United States
Gary
The price is NT$3,353
NT$3,806 total
includes taxes & fees
Jun 22 - Jun 23
The Eagles Nest Inn

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
26.3 km from Mississippi River
6.4 out of 10, (775 reviews)
"The staff were very friendly and helpful, The breakfast was probably the best we had experienced at any hotel where we have stayed. If we pass through the area again, we will likely choose to stay there again."
United States
Carol
The price is NT$1,988
NT$2,309 total
includes taxes & fees
Jun 28 - Jun 29
Baymont by Wyndham Hannibal

Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,000 reviews)
"Clean rooms, decent breakfast"
United States
Christina
The price is NT$3,485
NT$4,020 total
includes taxes & fees
Jun 28 - Jun 29
Best Western On The River

Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.4 out of 10, Exceptional, (179 reviews)
"Surprisingly fun property, clean, quiet (except for the train whistles). Hot tub was a great addition! Close to downtown fun! Would stay here again!"
United States
Michael
The price is NT$5,380
NT$7,298 total
includes taxes & fees
Jun 19 - Jun 20
Riverside Inn Hannibal

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
9.0 out of 10, Wonderful, (30 reviews)
"Fun themed rooms."
United States
Kelly
The price is NT$5,394
NT$7,315 total
includes taxes & fees
Jun 18 - Jun 19
Lighthouse Inn & Suites

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
86.8 km from Mississippi River
6.4 out of 10, (546 reviews)
"Room was clean but basic"
United States
James
The price is NT$2,209
NT$2,506 total
includes taxes & fees
Jun 28 - Jun 29
Economy Inn Wentzville

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,001 reviews)
"Room was great and breakfast was fantastic "
United States
Sheila
The price is NT$3,869
NT$4,502 total
includes taxes & fees
Jun 28 - Jun 29
Sleep Inn & Suites Hannibal West

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1,010 reviews)
"Nice staff, good parking, clean room."
United States
Susan
The price is NT$1,704
NT$1,965 total
includes taxes & fees
Jun 29 - Jun 30
Motel 6 Hannibal, MO

Garden House Bed and Breakfast

Garden House Bed and Breakfast
2.0 star property
25.2 km from Mississippi River
8.4 out of 10, Very Good, (43 reviews)
"Very welcoming hosts, they went the extra mile and had a very comfortable bed! There were lots of cool antiques and they knew a lot of history on the home itself. We would recommend staying here again. "
United States
Andy Nicole
The price is NT$3,365
NT$3,881 total
includes taxes & fees
Jun 24 - Jun 25
Garden House Bed and Breakfast

Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
26.4 km from Mississippi River
7.4 out of 10, Good, (250 reviews)
"A good place to stay in Hannibal."
United States
Marcia
The price is NT$2,046
NT$2,360 total
includes taxes & fees
Jun 21 - Jun 22
Days Inn by Wyndham Hannibal

Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (1,004 reviews)
"Property was clean and staff was friendly."
United States
Etta
The price is NT$1,988
NT$2,293 total
includes taxes & fees
Jun 29 - Jun 30
Super 8 by Wyndham Hannibal

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (705 reviews)
"As always the beds at comfort inn are so comfortable. Enjoyed our stay."
United States
Tracey
The price is NT$2,729
NT$3,243 total
includes taxes & fees
Jul 12 - Jul 13
Comfort Inn & Suites - Hannibal

LAKEVIEWINN

LAKEVIEWINN
2.5 star property
89.4 km from Mississippi River
6.0 out of 10, (54 reviews)
"Good place to stay"
United States
Jeremy
The price is NT$2,131
NT$2,407 total
includes taxes & fees
Jul 12 - Jul 13
LAKEVIEWINN

Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk
2.5 star property
96.1 km from Mississippi River
6.2 out of 10, (521 reviews)
"Room was very clean, A/C worked great. Exterior of the property is a bit rough but besides that the stay was good! Friendly staff"
United States
Adam
The price is NT$2,330
NT$2,610 total
includes taxes & fees
Jun 21 - Jun 22
Baymont by Wyndham Keokuk

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
30 km from Mississippi River
8.0 out of 10, Very Good, (1,015 reviews)
"Parking was easy and safe, when the staff was available, they were courteous, and breakfast was good."
United States
Dan
The price is NT$2,373
NT$2,761 total
includes taxes & fees
Jul 12 - Jul 13
Quality Inn & Suites Hannibal West

La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North
3.0 star property
109.6 km from Mississippi River
6.6 out of 10, (1,013 reviews)
"Great stay"
United States
Micaela
The price is NT$2,120
NT$2,591 total
includes taxes & fees
Jul 12 - Jul 13
La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

Sleep Inn Saint Charles North

Sleep Inn Saint Charles North
2.5 star property
97.1 km from Mississippi River
5.8 out of 10, (543 reviews)
"I enjoy my fligth"
United States
Eulogio
The price is NT$2,573
NT$2,957 total
includes taxes & fees
Jul 3 - Jul 4
Sleep Inn Saint Charles North

Extended Stay America Select Suites St Louis Earth City

Extended Stay America Select Suites St Louis Earth City
2.5 star property
107.1 km from Mississippi River
6.6 out of 10, (911 reviews)
"Not a bad place"
United States
Robert
The price is NT$2,840
NT$3,395 total
includes taxes & fees
Jul 5 - Jul 6
Extended Stay America Select Suites St Louis Earth City

Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn
2.5 star property
103.4 km from Mississippi River
5.6 out of 10, (1,015 reviews)
"The pool was out of order which was one of the reasons for our trip. We got locked out of our room when coming back but the staff was nice and the rooms was clean"
United States
teri
The price is NT$2,414
NT$2,798 total
includes taxes & fees
Jun 18 - Jun 19
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mississippi River

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Property grounds
River's Edge Motel
2.0 star property
9.0
Wonderful
367 reviews
View
Lunch and dinner served
The Eagles Nest Inn
3.0 star property
9.4
Exceptional
25 reviews
View
Indoor pool
Baymont by Wyndham Hannibal
2.5 star property
6.4
775 reviews
View
Desk, iron/ironing board, WiFi, bed sheets
Best Western On The River
2.5 star property
8.6
Excellent
1,000 reviews
View
55-inch TV with cable channels, Netflix, Hulu
Riverside Inn Hannibal
2.5 star property
9.4
Exceptional
179 reviews
View

Top Mississippi River Hotel Reviews

Hotels near other Mississippi River attractions

Find out more about Mississippi River

Top reasons to visit Mississippi River

  • Vibrant Atmosphere: Experience exciting activities like baseball games, live music, and thrilling water parks along the scenic Mississippi River.
  • Outdoor Adventures: Discover hiking and nature walks at Mississippi River State Park, ideal for nature enthusiasts.
  • Cultural Exploration: Immerse yourself in local history with captivating caves, historic houses, and lighthouses.
  • Charming Cities: Visit vibrant cities like Memphis and New Orleans, offering stunning river views and lively downtowns.
  • Diverse Accommodations: Choose from cozy bed and breakfasts to waterfront hotels for a memorable stay.

Find great hotels near Mississippi River

Explore the enchanting Mississippi River with a variety of hotel accommodations tailored to your needs. From charming bed and breakfasts to cozy guesthouses, you'll find ideal lodging for family getaways, romantic retreats, or historic adventures. Whether you're seeking a waterfront hotel or the best hotels near the river, the options available promise unforgettable experiences along this iconic waterway. Enjoy the perfect blend of comfort and convenience on your journey through this captivating region.

  • Best Western On The River: Nestled 25.7km from the majestic Mississippi River, Best Western On The River is a welcoming retreat for both business travelers and families seeking a memorable vacation. This hotel emphasizes family-friendly amenities, including a PoolGate for safety and cribs available for a small fee. The blend of comfort and convenience makes it an ideal choice for visitors looking to balance work and leisure while enjoying regional attractions.
  • Super 8 by Wyndham Bowling Green: Located 24.1km from the Mississippi River, Super 8 by Wyndham Bowling Green is a budget-friendly option that doesn’t skimp on comfort. Guests can indulge in complimentary breakfast options, including ToGoBreakfast and daily breakfast offerings, ensuring a great start to each day. The entertainment options are plentiful with a television, satellite TV, and even a DVD player, making it a perfect spot for relaxation after a day of exploring.
  • River's Edge Motel: Just 12.9km away from the iconic Mississippi River, River's Edge Motel is a haven for pet lovers looking to enjoy a vacation without leaving their furry friends behind. This motel welcomes pets with certain restrictions, and service animals are accommodated without additional fees. With its laid-back atmosphere and focus on pet-friendly amenities, it provides a unique and comfortable experience for those traveling with pets.

Where to stay near Mississippi River

Experience the charm and warmth of the Mississippi River region, where friendly locals and family-friendly attractions abound. Explore vibrant cities like Memphis and New Orleans, both offering stunning river views and downtown locations perfect for a weekend getaway. Enjoy relaxing excursions along the river, taking in the picturesque scenery and unique atmosphere that make this area a delightful destination for every traveler.

  • Louisiana: Nestled 14.5km from the Mississippi River, Louisiana is a charming city that offers a blend of outdoor activities and scenic beauty. This destination is especially popular during the spring and summer months, with peak visitor numbers in April, July, and September. Travelers are drawn to Louisiana for its romantic ambiance and ample opportunities for outdoor adventures. Key attractions include an arena entertainment facility, an amusement park, and an arcade adventure zone, making it a perfect spot for family fun. Additionally, the nearby river, lake, and island provide picturesque settings that enhance the overall travel experience.
  • New Canton: Located 11.3km from the Mississippi River, New Canton is a delightful city that offers seasonal experiences for visitors, particularly during the winter and spring months, with peak travel times in January, February, April, August, and November. Known for its outdoor adventures and scenic landscapes, New Canton is a haven for nature enthusiasts. Popular activities include golfing at local country clubs and exploring the national state park. The close proximity of the river and lake adds to the area's allure, providing stunning views and recreational opportunities.
  • Rockport: A vibrant city situated 12.9km from the Mississippi River, Rockport welcomes tourists with a rich cultural experience and a city-themed atmosphere. The peak travel seasons occur in May, July, and September, making it an ideal time to explore its educational venues and modern college university. Rockport's blend of culture and city life offers plenty of opportunities for visitors to engage with local art and history, making it a worthwhile stop on your journey along the Mississippi River.

Things to do near Mississippi River

Experience the vibrant atmosphere along the Mississippi River with exciting activities such as baseball games, live music, and thrilling water parks. Enjoy memorable stays while exploring the scenic riverfront with paddle boats and engaging in free activities. Don’t miss the captivating river shows that showcase the beauty and culture of the region, making your visit truly unforgettable.

Shopping

For a great shopping experience, visit Quincy Mall, located 46.7km away from the Mississippi River. This shopping center offers a mix of entertainment and family-friendly vibes, making it perfect for finding gifts and souvenirs during your stay.

Recreation

At Old Orchard Country Club, enjoy a round of golf surrounded by lush landscapes and a vibrant outdoor atmosphere, only 33.8km from the Mississippi River. Westview Golf Course, 43.5km away, offers a similar outdoor experience, while Norwoods Golf Club, just 32.2km from the river, provides an inviting golfing vibe.

Adventure

Greeman Tennis Center, located 48.3km from the Mississippi River, offers an exhilarating experience for tennis enthusiasts. Embrace the adventure vibes as you engage in friendly matches and enjoy the vibrant atmosphere, perfect for both beginners and seasoned players looking to challenge their skills.

Nightlife

Along the Mississippi River, nightlife comes alive at Bluff City Theater and Planters Barn Theater, both 25.7km away. These venues exude romance and culture, offering captivating performances that immerse you in the local entertainment scene and create unforgettable evening experiences.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Mississippi River

To save money during your visit to the Mississippi River, consider traveling between December and February for lower accommodation rates, with Sundays being the cheapest days to stay. Use Expedia to compare hotel prices and find exclusive offers, and consider bundling your hotel, flights, and activities for additional savings. Look for Eco-certified hotels for sustainable options. Also, explore free activities along the river, such as parks and walking trails, to enhance your experience without breaking the bank.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Mississippi River are December to February, where the prices are slightly lower. This is in comparison to May to July, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Mississippi River is Sunday. The most expensive day to stay around Mississippi River is Saturday.
  • Find cheap hotels on Expedia: Expedia's search tool enables you to choose your budget, desired location, and additional preferences. You can arrange your search results to display prices from lowest to highest, making it easy to find the most affordable hotels first. Additionally, you have the option to narrow down your choices by hotel type; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels that you can reserve.
  • Consider bundling your trip: You can save money by combining your hotel stay along the Mississippi River with your flights and activities through an Expedia package.

Find the best attractions near Mississippi River

Explore the vibrant Mississippi River, where you can discover captivating caves, historic houses, and lighthouses. Enjoy outdoor adventures at Mississippi River State Park, perfect for hiking and nature walks. Immerse yourself in the local culture and history, while seeking thrilling experiences along the river. Whether you're after adventure or relaxation, the Mississippi River offers a diverse range of attractions for every traveler.

  • Mark Twain Cave: Experience the thrill of adventure as you explore Mark Twain Cave, a fascinating natural wonder located 19.3km from the Mississippi River. With its stunning rock formations and underground passages, the cave offers a unique outdoor adventure vibe that will leave you in awe.
  • Mark Twain Boyhood Home and Museum: Immerse yourself in the rich culture of American literature at the Mark Twain Boyhood Home and Museum, situated 25.7km away. Discover the life and inspirations of Samuel Clemens in this historic house that captures the essence of his childhood.
  • Sawyer's Creek Fun Park: Enjoy a fun-filled day at Sawyer's Creek Fun Park, located 22.5km from the river. This urban park offers a family-friendly atmosphere with various outdoor activities, perfect for creating lasting memories with loved ones.

The nearest major airports for your trip to Mississippi River

Traveling to the Mississippi River can be convenient with two major airports nearby. St. Louis, MO (SUS-Spirit of St. Louis) is 107.8km away, offering hotel options like the 4.5-star Ameristar Casino Resort and Spa, located 17.7km from the airport, and the 4-star DoubleTree by Hilton Hotel St. Louis - Chesterfield, just 6.4km away. Quincy, IL (UIN-Quincy Regional-Baldwin Field) is closer at 43.5km, with accommodations such as the 3-star Holiday Inn Quincy East, 12.9km from the airport. Each airport has accessible transportation services available from these hotels to ensure a seamless travel experience.

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travelers like for its baseball games. When you want to settle in and find a place to stay, check out some of the hotels and other accommodations that Expedia offers in the area.
What's the best place to stay close to Mississippi River?
Hyatt Regency St. Louis at The Arch is one of the top choices for your stay based on our traveler data, and this hotel offers 3 restaurants and 2 bars. You'll find it 82.1 mi (132.1 km) from Mississippi River. Other good options around the area include Hollywood Casino & Hotel St. Louis and Pear Tree Inn St. Louis Airport.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes, you'll find most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get top deals close to Mississippi River.
Where can I learn more about changing or cancelling my trip in the area near Mississippi River?
For additional details about updating your stay near Mississippi River or cancelling it, head over to our customer service page.