A bridge spanning a body of water with a city skyline in the background during sunset.

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Sep 16 - Sep 17
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Sep 17 - Sep 18
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Sep 18 - Sep 20
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Our top choices for Mississippi River hotels

1. The Eagles Nest Inn

The Eagles Nest Inn
14.2 km from Mississippi River
United States
Gary
NT$3,578
NT$4,063 total
includes taxes & fees
Sep 20 - Sep 21
The Eagles Nest Inn

2. Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
30.3 km from Mississippi River
United States
Patricia
NT$3,488
NT$4,058 total
includes taxes & fees
Oct 11 - Oct 12
Sleep Inn & Suites Hannibal West

3. River's Edge Motel

River's Edge Motel
13.6 km from Mississippi River
United States
Paul
NT$2,640
NT$2,997 total
includes taxes & fees
Sep 30 - Oct 1
River's Edge Motel

4. Best Western On The River

Best Western On The River
25.3 km from Mississippi River
United States
Raymond
NT$3,505
NT$4,043 total
includes taxes & fees
Sep 20 - Sep 21
Best Western On The River

5. Riverside Inn Hannibal

Riverside Inn Hannibal
25.1 km from Mississippi River
United States
Jack
NT$5,132
NT$7,022 total
includes taxes & fees
Sep 20 - Sep 21
Riverside Inn Hannibal

6. Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
30 km from Mississippi River
United States
Tom
NT$2,614
NT$3,042 total
includes taxes & fees
Oct 11 - Oct 12
Quality Inn & Suites Hannibal West

7. Oak Hill Inn & Suites

Oak Hill Inn & Suites
71.8 km from Mississippi River
United States
Denny
NT$3,220
NT$3,670 total
includes taxes & fees
Oct 15 - Oct 16
Oak Hill Inn & Suites

8. Heritage Hotel Quincy

Heritage Hotel Quincy
47.8 km from Mississippi River
United States
Dustine
NT$2,477
NT$2,823 total
includes taxes & fees
Sep 26 - Sep 27
Heritage Hotel Quincy

9. Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
95.3 km from Mississippi River
United States
Melanie
NT$3,505
NT$4,030 total
includes taxes & fees
Oct 4 - Oct 5
Drury Inn & Suites St. Louis St. Peters

10. Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
104 km from Mississippi River
United States
Robert
NT$4,612
NT$5,346 total
includes taxes & fees
Sep 27 - Sep 28
Drury Plaza Hotel St. Louis St. Charles

11. Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG
93.3 km from Mississippi River
United States
Serah
NT$3,753
NT$4,511 total
includes taxes & fees
Sep 27 - Sep 28
Holiday Inn Express & Suites St Peters by IHG

12. Quality Inn & Suites Quincy - Downtown

Quality Inn & Suites Quincy - Downtown
47.8 km from Mississippi River
United States
Steve
NT$3,515
NT$4,006 total
includes taxes & fees
Oct 18 - Oct 19
Quality Inn & Suites Quincy - Downtown

13. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
26.2 km from Mississippi River
United States
Melanie
NT$2,467
NT$2,941 total
includes taxes & fees
Sep 20 - Sep 21
Comfort Inn & Suites - Hannibal

14. Stoney Creek Inn Quincy

Stoney Creek Inn Quincy
46.5 km from Mississippi River
United States
Kent
NT$3,330
NT$3,796 total
includes taxes & fees
Sep 20 - Sep 21
Stoney Creek Inn Quincy

15. Hampton Inn & Suites St. Louis/Alton

Hampton Inn & Suites St. Louis/Alton
110.3 km from Mississippi River
United States
Kristen
NT$4,147
NT$4,727 total
includes taxes & fees
Oct 18 - Oct 19
Hampton Inn & Suites St. Louis/Alton

16. Lighthouse Inn & Suites

Lighthouse Inn & Suites
25.8 km from Mississippi River
United States
Connie
NT$5,708
NT$6,585 total
includes taxes & fees
Sep 20 - Sep 21
Lighthouse Inn & Suites

17. Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
103.7 km from Mississippi River
United States
Susan Greening.
NT$3,893
NT$4,474 total
includes taxes & fees
Oct 11 - Oct 12
Country Inn & Suites by Radisson, St. Charles Historic District

18. Garden House Bed and Breakfast

Garden House Bed and Breakfast
25.2 km from Mississippi River
United States
Edward
NT$2,947
NT$3,399 total
includes taxes & fees
Sep 23 - Sep 24
Garden House Bed and Breakfast

19. The Green Tree Inn

The Green Tree Inn
95 km from Mississippi River
United States
Karen
NT$6,524
NT$7,240 total
includes taxes & fees
Sep 23 - Sep 24
The Green Tree Inn

20. Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
46.1 km from Mississippi River
United States
Charles
NT$3,920
NT$4,468 total
includes taxes & fees
Sep 27 - Sep 28
Holiday Inn Quincy East by IHG
View all properties

Compare popular hotels close to Mississippi River

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Restaurant
The Eagles Nest Inn
9.4
Exceptional
26 reviews
View
Exterior
Sleep Inn & Suites Hannibal West
9.6
Exceptional
1,002 reviews
View
Property grounds
River's Edge Motel
9.0
Wonderful
387 reviews
View
Room
Best Western On The River
8.8
Excellent
1,000 reviews
View
Living room
Riverside Inn Hannibal
9.6
Exceptional
196 reviews
View

Top Mississippi River Hotel Reviews

The Cheshire

The Cheshire

8/10 Good
"Charming and quaint alternative to a Holiday Inn. It was renovated 10-15 years ago but not much care since then. The pool was allegedly open still (mid September) but when we looked out to go use it, there was debris in it and it wasn’t very inviting. The price was affordable and it was pet friendly, I only wish we could have experienced it during its heyday years ago when it was properly maintained and cleaned."
Ed 3-night trip
Posted 3 hours ago
The Cheshire
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent
"The ice/microwave rooms are weird and only on every other floor. The rooftop bar is excellent, as is the art!"
Karen 3-night trip
Posted 6 hours ago
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

8/10 Good
"The staff was stellar, answered questions before I thought of them, knew the area and were efficient, housekeeping staff offered help and suggestions and were a highlight but front desk staff was great too. The parking garage was adequate, but parking before you checked in wasn't great (they offered a few 15 minute stalls and most folks clogged up the entrance area after that, so a bit cramped), but the garage itself wasn't bad. Room was clean, was were the public areas. Overall a nice stay!."
David 1-night trip
Posted 6 hours ago
Drury Plaza Hotel St. Louis Union Station
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent
"Great location, very clean. Highly recommend!"
Tina 1-night trip
Posted 9 hours ago
Drury Plaza Hotel St. Louis at the Arch
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent
"We will stay here again. Good bkfst, convenient. Nice pool & spa."
Penny 1-night trip
Posted 9 hours ago
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"We enjoyed the hotel. Lobby was beautiful and staff was helpful."
KYLE 1-night trip
Posted 9 hours ago
Clayton Plaza Hotel & Extended Stay
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent
"Room was clean and comfy. Breakfast was Delicious 😋"
Abel 1-night trip
Posted 1 day ago
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

10/10 Excellent
"We only spent one night but the room was gorgeous the checking was easy and the employees were great. The food at the restaurants were also good and of course we did enjoy our time at the casino"
John 1-night trip
Posted 1 day ago
Ameristar Casino Resort and Spa
21C Museum Hotel St Louis

21C Museum Hotel St Louis

10/10 Excellent
"Great location, spacious room."
Guillaume 1-night trip
Posted 1 day ago
21C Museum Hotel St Louis

Other attractions near Mississippi River

Mark Twain Cave

8.8/10 (89 reviews)
You can find out about the history of Hannibal with a visit to Mark Twain Cave. While in this trendy area, you can savor the top-notch restaurants.
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Sawyer's Creek Fun Park

7.8/10 (16 reviews)
Explore the great outdoors at Sawyer's Creek Fun Park, a lovely green space in Hannibal. While in this walkable area, you can savor the top-notch restaurants.
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Lovers Leap

8.8/10 (171 reviews)
Find out about the history of Hannibal with a stop at Lovers Leap. While in this walkable area, you can savor the top-notch restaurants.
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Sodalis Nature Preserve

Explore the great outdoors at Sodalis Nature Preserve, a lovely green space in Hannibal. While in this family-friendly area, you can savor the top-notch restaurants.
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Bluff City Theater

7.6/10 (5 reviews)
Enjoy a show at Bluff City Theater, a theater with a story to tell in Hannibal. While in this family-friendly area, you can savor the top-notch restaurants.
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Planters Barn Theater

8.8/10 (22 reviews)
Enjoy a show at Planters Barn Theater, a storied theater in Hannibal. While in this walkable area, you can savor the top-notch restaurants.
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Mark Twain Boyhood Home and Museum

9.0/10 (278 reviews)
Find out about the history of Hannibal when you take a trip to Mark Twain Boyhood Home and Museum. While in this family-friendly area, you can savor the top-notch restaurants.
See properties

Jim's Journey: The Huck Finn Freedom Center

8.4/10 (33 reviews)
You can browse the exhibits at Jim's Journey: The Huck Finn Freedom Center, a museum with a story of its own, during your travels to Hannibal. While in this family-friendly area, you can savor the top-notch restaurants.
See properties

Find out more about Mississippi River

Top reasons to visit Mississippi River

  • Scenic River Views: Experience breathtaking sights along the majestic Mississippi River, including iconic landmarks like the Memphis Bridge.
  • Cultural Exploration: Immerse yourself in the rich history and vibrant culture of the Mississippi Delta and nearby cities like Minneapolis.
  • Outdoor Activities: Enjoy bird watching, leisurely floating, and family-friendly adventures in beautiful natural settings.
  • Historic Attractions: Discover charming historic houses, intriguing caves, and engaging museums throughout the region.
  • Cozy Accommodations: Choose from a variety of charming bed & breakfasts and guesthouses for a memorable stay.

Find great hotels near Mississippi River

Discover a variety of hotel accommodations along the picturesque Mississippi River, where you can choose from charming bed & breakfasts and cozy guesthouses. Ideal for families, couples, and history enthusiasts, these lodging options provide a unique blend of comfort and romantic appeal. Whether you’re interested in rustic wilderness cabins or modern amenities at places like the Hampton Inn, the Mississippi River has something to make your stay memorable.

  • Best Western On The River: Nestled in the heart of the city, Best Western On The River is a budget-friendly lodging option with a guest rating of 8.6 out of 10. Located 26km from the Mississippi River, this hotel is ideal for families and business travelers alike. It features child-friendly amenities, including a PoolGate, making it a great choice for those traveling with kids. Its central location allows easy access to local attractions and dining options, ensuring a convenient stay while exploring the area.
  • Super 8 by Wyndham Bowling Green: With a guest rating of 8.4 out of 10, Super 8 by Wyndham Bowling Green offers a budget-friendly stay just 24km from the Mississippi River. This motel is well-known for its complimentary breakfast options, including daily free breakfast and to-go breakfast services, making it a great start to your day. Entertainment options abound with multiple television channels available for guests to enjoy. The welcoming atmosphere and essential amenities make it a suitable choice for travelers seeking comfort on a budget.
  • River's Edge Motel: River's Edge Motel boasts a guest rating of 9.0 out of 10 and is located a mere 13km from the Mississippi River. This pet-friendly motel is perfect for travelers who want to bring their furry companions along. The property features accommodating pet policies, allowing for a seamless stay with your pets. Its rustic charm and proximity to the river create a warm and inviting atmosphere, making it an excellent option for those seeking a cozy getaway in a natural setting.

Where to stay near Mississippi River

Your vacation along the Mississippi River promises a delightful blend of friendly people and family-friendly activities. Explore vibrant cities like Minneapolis near the Minnesota River, or immerse yourself in the rich culture of the Mississippi Delta. Enjoy relaxing excursions along the main river and the scenic Iowa River, each offering unique experiences and warm hospitality. Get ready to create unforgettable memories in this beautiful region.

  • Louisiana: Louisiana is a charming city located 14km from the Mississippi River, offering a delightful mix of outdoor activities and scenic views. The city experiences a steady flow of visitors throughout the year, with peak times in April, July, and September. Travelers are drawn here for its romantic atmosphere and recreational opportunities. Enjoy the local theater scene or explore nearby entertainment venues. Notable attractions include the picturesque river, serene lake, and the expansive national state park, making Louisiana a perfect getaway for nature lovers and couples alike.
  • New Canton: Situated 11km away from the Mississippi River, New Canton is a quaint city that attracts visitors with its seasonal charm. The peak travel months are January to February, April, August, and November. Families often visit to enjoy the beautiful scenery and partake in outdoor activities. Golf enthusiasts will appreciate the local golf courses, while those interested in education can explore various learning opportunities. Key landmarks include the nearby river, tranquil lake, and a fascinating natural history museum, ensuring a well-rounded experience for all ages.
  • Rockport: Located 13km from the Mississippi River, Rockport is a vibrant city that offers a blend of outdoor adventures and family-friendly attractions. The city sees an influx of visitors during May, July, and September, making it a popular choice for those seeking a city-themed experience. Enjoy educational outings, catch a show at the local theater, or hit the golf course for a day of fun. Rockport’s notable landmarks include an urban park, an engaging history museum, and a modern college university, providing a unique cultural experience for travelers.

Things to do in Mississippi River

Shopping

In the Mississippi River area, visit the Riverwalk Marketplace for unique gifts and local crafts. If you're up for a drive, head to the Mall of America, about 24km away, featuring a wide range of shops and dining options for a fun shopping experience.

Recreation

Experience the tranquility of the River View Wellness Retreat, where you can indulge in yoga classes and spa treatments surrounded by nature. Enjoy leisurely strolls along the riverbanks and rejuvenate with guided meditation sessions to enhance your overall well-being.

At the Mississippi River Spa, immerse yourself in a soothing environment with massages and wellness therapies. Participate in outdoor activities like kayaking or biking along the scenic river trails for a refreshing blend of relaxation and adventure.

Adventure

The Mississippi River offers thrilling kayaking and canoeing experiences, allowing you to paddle through stunning landscapes. Explore vibrant wildlife on guided riverboat tours or try your hand at fishing in its bountiful waters. For a unique angle, consider a scenic bike ride along the riverfront trails.

Nightlife

The nightlife along the Mississippi River is vibrant and diverse. Enjoy live music at B.B. King's Blues Club in Memphis, or sip craft cocktails at Rooftop Bar in New Orleans. For a laid-back vibe, visit a local pub in Baton Rouge and soak in the lively atmosphere.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Mississippi River

To save money during your visit to the Mississippi River, consider traveling between December and February for lower accommodation rates, with Sundays being the cheapest days to stay. Use Expedia to compare hotel prices and find exclusive offers, and consider bundling your hotel, flights, and activities for additional savings. Look for Eco-certified hotels for sustainable options. Also, explore free activities along the river, such as parks and walking trails, to enhance your experience without breaking the bank.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Mississippi River are December to February, where the prices are slightly lower. This is in comparison to May to July, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Mississippi River is Sunday. The most expensive day to stay around Mississippi River is Saturday.
  • Find cheap hotels on Expedia: Expedia's search tool enables you to choose your budget, desired location, and additional preferences. You can arrange your search results to display prices from lowest to highest, making it easy to find the most affordable hotels first. Additionally, you have the option to narrow down your choices by hotel type; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels that you can reserve.
  • Consider bundling your trip: You can save money by combining your hotel stay along the Mississippi River with your flights and activities through an Expedia package.

Find the best attractions near Mississippi River

The Mississippi River offers a variety of attractions, including historic houses, caves, and museums, perfect for travelers seeking culture, outdoor activities, and family experiences. Explore the majestic Mississippi River itself, the scenic Chippewa River, the iconic Memphis Bridge, and the tranquil Mississippi River headwaters for a memorable vacation experience along this mighty waterway.

  • Mark Twain Boyhood Home and Museum: Explore the childhood home of Samuel Clemens, known as Mark Twain, in Hannibal, Missouri. This museum offers a glimpse into the author's early life and the influences that shaped his literary career. With engaging exhibits and guided tours, visitors can immerse themselves in the culture and history of the area.
  • Mark Twain Cave: Venture into the historic Mark Twain Cave, a site of adventure and exploration. Just 23km from the Mississippi River, this cave features fascinating rock formations and a rich history tied to Twain's storytelling. Guided tours provide insight into its natural beauty and geological significance.
  • Mark Twain Memorial Lighthouse: Visit this historic lighthouse, which stands as a tribute to Mark Twain's legacy. Located 26km from the river, the lighthouse offers scenic views of the Mississippi and serves as a cultural landmark, celebrating the region's literary heritage.

The nearest major airports for your trip to Mississippi River

Traveling to the Mississippi River can be done via several major airports. St. Louis Lambert International Airport (STL), located 113km away, offers hotels like The Ritz-Carlton and Ameristar Casino Resort and Spa, both just 11km from the airport. Greater Peoria Regional Airport (PIA), 175km distant, has options like Embassy Suites by Hilton and Peoria Marriott Pere Marquette, both within 10km. Columbia Regional Airport (COU) is 122km away, with nearby accommodations such as The Broadway Columbia - a DoubleTree by Hilton and voco The Tiger Hotel, both around 18km from the airport. Each location provides convenient transportation services for easy access.

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travelers like for its baseball games. When you want to settle in and find a place to stay, check out some of the hotels and other accommodations that Expedia offers in the area.
What's the best place to stay close to Mississippi River?
Hollywood Casino & Hotel St. Louis is one of the top choices for your stay based on our traveler data, and this hotel offers a casino and 7 restaurants. You'll find it 65.7 mi (105.7 km) from Mississippi River. Other good options around the area include Hyatt Regency St. Louis at The Arch and Clayton Plaza Hotel & Extended Stay.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes, you'll find most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get top deals close to Mississippi River.
Where can I learn more about changing or cancelling my trip in the area near Mississippi River?
For additional details about updating your stay near Mississippi River or cancelling it, head over to our customer service page.