Find hotels in Mesopotamia

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Nov 22 - Nov 23
Tomorrow
Nov 23 - Nov 24
Next weekend
Nov 28 - Nov 30
In two weeks
Dec 5 - Dec 7

Filter by

Guest rating
Guest rating
Star rating

Compare hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Interior
To Spiti tis Sofias

To Spiti tis Sofias

Kastoria
10.0 out of 10, Exceptional, (1)
"Tout simplement le meilleur de notre voyage en Grèce. Simple mais tellement mieux qu'ailleurs. Accueil parfait, chambre confortable et petit déjeuner de roi. Je reviendrais à 100% si je passe dans le coin. "
France
Anonymous traveler
The price is NT$2,285
NT$2,613 total
includes taxes & fees
Nov 23 - Nov 24
To Spiti tis Sofias
3 restaurants, breakfast, lunch, dinner served; Greek cuisine
Limneon Resort & Spa

Limneon Resort & Spa

4.0 star property
Kastoria
9.2 out of 10, Wonderful, (197)
"Wonderful stay. "
Canada
Konstantinos
The price is NT$3,332
NT$3,892 total
includes taxes & fees
Nov 23 - Nov 24
Limneon Resort & Spa
Free daily buffet breakfast
Chloe Hotel

Chloe Hotel

3.0 star property
Kastoria
10.0 out of 10, Exceptional, (86)
"We enjoyed the stay, friendly staff and nice breakfast "
Australia
Fani
The price is NT$3,173
NT$3,658 total
includes taxes & fees
Nov 23 - Nov 24
Chloe Hotel
Breakfast, lunch and dinner served
Esperos Palace Luxury & Spa Hotel

Esperos Palace Luxury & Spa Hotel

4.0 star property
Kastoria
9.0 out of 10, Wonderful, (84)
"The hotel is beautiful, large room with balcony. Grate bathroom, comfortable, the dinner is good ,however the breakfast was amazing. "
United States
Michal
The price is NT$3,015
NT$3,532 total
includes taxes & fees
Nov 23 - Nov 24
Esperos Palace Luxury & Spa Hotel
Deluxe Double or Twin Room | Minibar, in-room safe, soundproofing, iron/ironing board
Orologopoulos Mansion

Orologopoulos Mansion

5.0 star property
Kastoria
9.6 out of 10, Exceptional, (36)
"Ideal accommodation in a tranquil area of the town, surrounded by character buildings. Several quality eating locations near by."
Australia
Mark
The price is NT$3,758
NT$4,412 total
includes taxes & fees
Nov 25 - Nov 26
Orologopoulos Mansion
Front of property - evening/night
Hotel Anastassiou

Hotel Anastassiou

2.0 star property
Kastoria
8.0 out of 10, Very Good, (68)
"Nice simple stay."
United States
Jeffrey
The price is NT$1,587
NT$1,820 total
includes taxes & fees
Nov 25 - Nov 26
Hotel Anastassiou
Property grounds
Calma Hotel & Spa

Calma Hotel & Spa

4.0 star property
Kastoria
9.6 out of 10, Exceptional, (35)
"Pleasant stay. Good amenities. Great staff. "
New Zealand
Robert
Calma Hotel & Spa
Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds
Kyknos De Luxe Hotel

Kyknos De Luxe Hotel

Kastoria
10.0 out of 10, Exceptional, (43)
"Very nice clean, very polite staff and great breakfast!"
United States
Vasilios
The price is NT$2,792
NT$3,225 total
includes taxes & fees
Nov 23 - Nov 24
Kyknos De Luxe Hotel
Garden
Guesthouse Vissinokipos

Guesthouse Vissinokipos

Kastoria
9.4 out of 10, Exceptional, (10)
"Wonderfull view and very friendly people.the place is avery dpecial artistic decorated.wonderfull weather.nice varieties for breakfast.price was ver good.i recommend it!"
United States
Carmen
Guesthouse Vissinokipos
Exterior
Arhontiko Christodoulou

Arhontiko Christodoulou

2.0 star property
Prespes
Arhontiko Christodoulou
Exterior
Guest House Ilektra

Guest House Ilektra

Voio
9.6 out of 10, Exceptional, (9)
"Wonderful views, easy to find, spacious rooms, and great hospitality."
United Kingdom
Maria
The price is NT$1,904
NT$2,180 total
includes taxes & fees
Dec 5 - Dec 6
Guest House Ilektra
Exterior
Andromeda Boutique hotel

Andromeda Boutique hotel

4.0 star property
Kastoria
8.8 out of 10, Excellent, (3)
Andromeda Boutique hotel
Property grounds
Anesis Hotel

Anesis Hotel

2.0 star property
Kastoria
9.0 out of 10, Wonderful, (9)
"Fantastic hotel in the heart of Kastoria. The owners are lovely people, very helpful and made me feel right at home. Will definitely stay there again!"
Canada
Adam
The price is NT$1,745
NT$2,000 total
includes taxes & fees
Nov 25 - Nov 26
Anesis Hotel
Room amenity
Guesthouse Monopati

Guesthouse Monopati

Amyntaio
10.0 out of 10, Exceptional, (3)
Guesthouse Monopati
Apartment | 3 bedrooms, Internet
The Sunset Haven Kastoria Modern Lake Elegance

The Sunset Haven Kastoria Modern Lake Elegance

Kastoria
The price is NT$3,911
NT$6,670 total
includes taxes & fees
Nov 23 - Nov 24
The Sunset Haven Kastoria Modern Lake Elegance
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Mesopotamia Hotel Reviews

Kyknos De Luxe Hotel

Kyknos De Luxe Hotel

10/10 Excellent
"The staff was warm and welcoming. The rooms were amazing and the breakfast was fantastic. Lots of ethnic Greek foods"
Theodora 4-night trip
Posted 3 weeks ago
Kyknos De Luxe Hotel

Frequently asked questions

Where is the best place for a stay in Mesopotamia?
To Spiti tis Sofias is one of the top choices for your stay based on our traveler data. This guesthouse offers free parking and free WiFi. Two other choices for your visit to the area are Limneon Resort & Spa and Esperos Palace Luxury & Spa Hotel. See all available top hotels, or vacation rentals in Mesopotamia.
What are some of the best vacation home rentals that Mesopotamia has to offer?
The Sunset Haven Kastoria Modern Lake Elegance: This vacation home rental outside of Mesopotamia offers a barbecue grill and free WiFi to help you feel comfortable in your new surroundings. See all vacation rentals in Mesopotamia.
If I need to cancel my hotel reservation in Mesopotamia, will I receive a refund?
Yes! You'll find that most room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Mesopotamia.
Where can I learn more about changing or cancelling my trip to Mesopotamia?
For more details about picking new dates or cancelling your trip to Mesopotamia, click here.
What is the best accommodation for staying close to Macedonia Airport (SKG)?
Hyatt Regency Thessaloniki is a popular 5-star hotel featuring 2 outdoor pools and a full-service spa. It's located a short 1.1 mi (1.8 km) from Macedonia Airport. Other options near the airport are Athina Airport Hotel and Hotel Nikopolis.
What is staying in Mesopotamia like?
Travelers to Mesopotamia will find plenty to explore and enjoy. There are 44 hotels and other accommodations in the surrounding area. Find out more about Mesopotamia.
What are the top places to visit in Mesopotamia?
Places to visit in the wider area include Kastoria Lake, Folklore Museum of Kastoria, and Holy Monastery of Panagias Mauriotissas. You'll also find Kastoria Aquarium and Byzantine Museum of Kastoria in the area. Check out what more to see and do in Expedia's Mesopotamia guide.
What's the seasonal weather like in Mesopotamia?
The hottest months are usually August and July with an average temp of 69°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for Mesopotamia is 28 inches.

Explore a world of travel with Expedia