An aerial view of a city with a prominent building labeled "ART" and a church with a green spire.

Find hotels in Main South, Worcester

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Sep 4 - Sep 6
Next weekend
Sep 11 - Sep 13

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Main South hotels

A modern living room with a fireplace, comfortable seating, and a large window.

1. AC Hotel by Marriott Worcester

AC Hotel by Marriott Worcester
3.5 star property
Worcester Central Business District, 2.1 km from Main South
9.4 out of 10, Exceptional, (1,002 reviews)
"A great experience…clean rooms, clean facility, quiet and well maintained."
United States
Jessica
The price is NT$5,666
NT$6,485 total
includes taxes & fees
Sep 6 - Sep 7
AC Hotel by Marriott Worcester
A modern lounge area with a stone wall, a fireplace, and a seating arrangement including sofas and a coffee table.

2. Homewood Suites By Hilton Worcester

Homewood Suites By Hilton Worcester
3.0 star property
Worcester Central Business District, 2.5 km from Main South
9.2 out of 10, Wonderful, (1,001 reviews)
"My stay this time was amazing."
United States
Robin
The price is NT$5,295
NT$6,060 total
includes taxes & fees
Sep 9 - Sep 10
Homewood Suites By Hilton Worcester
An outdoor seating area with wicker furniture and blue cushions, string lights overhead, and a fire feature in the center.

3. Hampton Inn & Suites Worcester

Hampton Inn & Suites Worcester
2.5 star property
3.2 km from Main South
9.0 out of 10, Wonderful, (1,000 reviews)
"The rooms were spacious and clean,the breakfast was hot and very good,and the staff was excellent and went above and beyond"
United States
Steve
The price is NT$4,386
NT$5,020 total
includes taxes & fees
Sep 9 - Sep 10
Hampton Inn & Suites Worcester
A hotel room with a sofa, a desk, a small table, a kitchenette, and a hallway with a painting.

4. Holiday Inn Express Hotel & Suites Auburn by IHG

Holiday Inn Express Hotel & Suites Auburn by IHG
2.5 star property
6.9 km from Main South
8.8 out of 10, Excellent, (1,000 reviews)
"The buffet breakfast was very good especially the cinnamon bun and the muffins,"
United States
Brian
The price is NT$3,197
NT$3,571 total
includes taxes & fees
Sep 13 - Sep 14
Holiday Inn Express Hotel & Suites Auburn by IHG
A dining area with a central island featuring a fruit bowl and a salad.

5. Hilton Garden Inn Worcester

Hilton Garden Inn Worcester
3.0 star property
Worcester Central Business District, 2.5 km from Main South
8.0 out of 10, Very Good, (1,000 reviews)
"Clean rooms and convenient access to Worcester University."
United States
Frederik Karl
The price is NT$4,257
NT$4,872 total
includes taxes & fees
Sep 9 - Sep 10
Hilton Garden Inn Worcester
An outdoor seating area with wicker furniture and a fire pit.

6. Courtyard by Marriott Worcester

Courtyard by Marriott Worcester
3.0 star property
3.1 km from Main South
8.4 out of 10, Very Good, (1,001 reviews)
"Great location. Room was clean and staff was helpful. Close to WPI campus if you are visiting."
United States
Jennifer
The price is NT$4,957
NT$5,673 total
includes taxes & fees
Sep 7 - Sep 8
Courtyard by Marriott Worcester
A hotel entrance with a covered walkway, a parking area, and a well-lit building facade.

7. Hampton Inn Auburn

Hampton Inn Auburn
2.5 star property
8.1 km from Main South
8.6 out of 10, Excellent, (1,001 reviews)
"The property was nice I was renovated nicely. But didn’t really too much like the staff"
United States
Alaysha
The price is NT$3,478
NT$3,885 total
includes taxes & fees
Sep 13 - Sep 14
Hampton Inn Auburn
A pool table with billiard balls, a fireplace, and a dining area with chairs and a table.

8. Residence Inn by Marriott Worcester

Residence Inn by Marriott Worcester
3.0 star property
6 km from Main South
8.4 out of 10, Very Good, (1,001 reviews)
"Clean hotel. Staff was friendly. Great gym and decent breakfast options."
United States
Jennifer
The price is NT$5,096
NT$5,833 total
includes taxes & fees
Sep 7 - Sep 8
Residence Inn by Marriott Worcester
A hotel room with a bed, pillows, a nightstand with a lamp, and a power outlet.

9. La Quinta Inn by Wyndham Auburn Worcester

La Quinta Inn by Wyndham Auburn Worcester
3.0 star property
5.9 km from Main South
8.4 out of 10, Very Good, (104 reviews)
"Great price, great breakfast, and great staff"
United States
Jose
The price is NT$2,496
NT$2,788 total
includes taxes & fees
Sep 20 - Sep 21
La Quinta Inn by Wyndham Auburn Worcester
A Fairfield Inn & Suites by Marriott hotel with a covered entrance and landscaped surroundings.

10. Fairfield Inn & Suites by Marriott Worcester Auburn

Fairfield Inn & Suites by Marriott Worcester Auburn
3.0 star property
8.2 km from Main South
8.6 out of 10, Excellent, (739 reviews)
"Great stay"
United States
Marcus
The price is NT$3,134
NT$3,500 total
includes taxes & fees
Sep 13 - Sep 14
Fairfield Inn & Suites by Marriott Worcester Auburn
A hotel with a patio area featuring outdoor seating and a garden with blue hydrangea flowers.

11. Beechwood Hotel

Beechwood Hotel
4.0 star property
5.1 km from Main South
9.2 out of 10, Wonderful, (1,000 reviews)
"We had no issues at all. Stayed about 5 nights."
United States
Michelle
The price is NT$7,810
NT$8,939 total
includes taxes & fees
Sep 4 - Sep 5
Beechwood Hotel
A modern building with a red carpet entrance, stone facade, and a covered walkway.

12. enVision Hotel Worcester Downtown

enVision Hotel Worcester Downtown
2.0 star property
Worcester Central Business District, 2.7 km from Main South
7.6 out of 10, Good, (1,000 reviews)
"This property has been completely upgraded and rebranded. You should disregard any reviews (positive or negative from befor August 20,2026. The room was amazing but the staff was better. I had an issue that was my own fault and they went out of their way to help. The property really embraces the community and highlights the best of Worcester and it's history. I They don't habe their own restaurant but Mezval next door is fantastic. I especially appreciate the updated bathroom in the room...
United States
Matthew
The price is NT$4,730
NT$5,413 total
includes taxes & fees
Sep 6 - Sep 7
enVision Hotel Worcester Downtown
A cozy living room with a fireplace, wooden bookshelves, and comfortable seating.

13. Comfort Inn Auburn - Worcester

Comfort Inn Auburn - Worcester
2.5 star property
5.7 km from Main South
8.0 out of 10, Very Good, (1,226 reviews)
"Good location, pleasant staff, value"
United States
Patricia
The price is NT$2,671
NT$2,984 total
includes taxes & fees
Oct 1 - Oct 2
Comfort Inn Auburn - Worcester
A multi-story hotel with a prominent "Hyatt Place" sign, a covered entrance, and a parking lot.

14. Hyatt Place Marlborough/Apex Center

Hyatt Place Marlborough/Apex Center
3.0 star property
21.1 km from Main South
9.2 out of 10, Wonderful, (1,000 reviews)
"Breakfast menu was good. Place was clean and in good shape."
United States
Jeanne
The price is NT$4,031
NT$4,503 total
includes taxes & fees
Sep 11 - Sep 12
Hyatt Place Marlborough/Apex Center
A modern restaurant with a central bar, wooden paneling, and a high ceiling with skylights.

15. Embassy Suites by Hilton Boston Marlborough

Embassy Suites by Hilton Boston Marlborough
3.5 star property
21.6 km from Main South
9.4 out of 10, Exceptional, (1,076 reviews)
"Great staff Amazing team and great buffet"
United States
Monica Geraldine
The price is NT$4,351
NT$4,860 total
includes taxes & fees
Sep 6 - Sep 7
Embassy Suites by Hilton Boston Marlborough
A hotel room with a large bed, bedside tables, a TV, a wardrobe, and a window with curtains.

16. Spark By Hilton Northborough

Spark By Hilton Northborough
3.0 star property
13.6 km from Main South
9.0 out of 10, Wonderful, (228 reviews)
"Great stay and very clean space."
United States
Francis
The price is NT$3,218
NT$3,595 total
includes taxes & fees
Sep 9 - Sep 10
Spark By Hilton Northborough
A modern hotel dining area with a long table, chairs, and a television on the wall.

17. Hampton Inn Boston - Westborough

Hampton Inn Boston - Westborough
2.5 star property
19.6 km from Main South
9.2 out of 10, Wonderful, (1,000 reviews)
"Great place to stay"
United States
Cheri
The price is NT$4,269
NT$4,768 total
includes taxes & fees
Oct 4 - Oct 5
Hampton Inn Boston - Westborough
A hotel room with two beds, a nightstand with a phone and a clock, and a headboard with built-in lighting.

18. Holiday Inn Express Hotel & Suites Boston-Marlboro by IHG

Holiday Inn Express Hotel & Suites Boston-Marlboro by IHG
2.5 star property
24.2 km from Main South
8.6 out of 10, Excellent, (844 reviews)
"The staff at the front desk was fantastic- incredibly friendly and helpful. The coffee was amazing- on-the-spot fresh ground. Beds comfortable, hotel accessible, wonderful stay!"
United States
Beverly
The price is NT$3,319
NT$3,707 total
includes taxes & fees
Sep 7 - Sep 8
Holiday Inn Express Hotel & Suites Boston-Marlboro by IHG
A patio area with outdoor seating and a grill, surrounded by stone walls and small plants.

19. Homewood Suites by Hilton Marlborough

Homewood Suites by Hilton Marlborough
3.0 star property
20 km from Main South
9.2 out of 10, Wonderful, (564 reviews)
"We had a wonderful stay"
United States
Elena
The price is NT$4,506
NT$5,033 total
includes taxes & fees
Sep 20 - Sep 21
Homewood Suites by Hilton Marlborough
A restaurant with multiple dining tables set for guests, large windows offering a view of the outdoors, and a variety of hanging pendant lights.

20. Hilton Garden Inn Boston/Marlborough

Hilton Garden Inn Boston/Marlborough
3.0 star property
21.9 km from Main South
9.2 out of 10, Wonderful, (1,000 reviews)
"Staff was great and helpful."
United States
Thina
The price is NT$3,849
NT$4,299 total
includes taxes & fees
Sep 7 - Sep 8
Hilton Garden Inn Boston/Marlborough
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Main South

Find the best Main South areas and neighborhoods for the activities you enjoy most.
A historic white building with two towers and green windows, located at a city intersection.

Worcester Central Business District

If you're spending some time in Worcester Central Business District, DCU Center and Mechanics Hall are top sights worth seeing.

An indoor dining area with tables and chairs, large windows, and hanging light bulbs.
Photo by Lisa Frackiewicz
Open Photo by Lisa Frackiewicz

Shrewsbury Street

Shrewsbury Street might not have many top sights, but Union Station and EcoTarium are two attractions nearby that you can check out.

A red bridge over a calm lake with stone steps leading up to it.

Union HIll

While Union HIll isn't home to many top sights, Union Station and The Hanover Theatre for the Performing Arts are some notable places to visit nearby.

Piedmont

If you're looking for some top things to see and do in Piedmont and surrounding area, you can visit The Hanover Theatre for the Performing Arts and Mechanics Hall.

Franklin Plantation

While Franklin Plantation isn't home to many top sights, EcoTarium and Union Station are some notable places to visit nearby.

Top Main South Hotel Reviews

northborough inn

northborough inn

10/10 Excellent
"The staff was very helpful and the rooms were simple but very clean. Overall, a very good value."
Donald 1-night trip
Posted 7 hours ago
northborough inn

Frequently asked questions

What is Main South like?
Travelers will be sure to enjoy their time in Worcester's Main South neighborhood.
How many hotels are there in Main South?
Book one of Expedia's 6 hotels and other accommodations in Main South and start exploring everything Worcester has to offer.
If I need to cancel my hotel reservation in Main South, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you may still be able to cancel and get a refund within 24 hours of your booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Main South.
Where can I learn more about changing or cancelling my trip to Main South?
To find more details about picking new dates or cancelling your trip to Main South, head over to our customer service page.
What is there to do in this Worcester neighborhood?
Fitton Field, Fitton Baseball Field, and Fitton Field are just a few of the places to visit in and around Main South. While you're out sightseeing in Worcester, be sure to visit other sights like The Hanover Theatre for the Performing Arts or John J. Binienda Memorial Beach.

Explore a world of travel with Expedia