Madre de Dios Region Vacations & Trips

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  • Plan, book, travel with confidence

  • Better together

    Save up to NT$5,067 when you book a flight and hotel together*

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    With over 300,000 hotels worldwide, it's easy to create a perfect package

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Madre de Dios Region Hotel Deals

Libelula Hotel

Libelula Hotel

2 out of 5
Jr Puno No. 429 Tambopata Madre de Dios
Fully refundableReserve now, pay when you stay
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Libelula Hotel
Tronco Tambopata Adventure

Tronco Tambopata Adventure

3 out of 5
km 4.5 Corredor Turistico Tambopata Tambopata Madre de Dios
10/10 Exceptional! (1 review)
The guides for the tours were very knowledgeable. The food was great and plentiful. The people were kind and hospitable.

Reviewed on 2025/9/10

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Tronco Tambopata Adventure
Inkaterra Hacienda Concepcion

Inkaterra Hacienda Concepcion

3.5 out of 5
Rio Madre de Dios Km. 7 Tambopata
9.4/10 Exceptional! (40 reviews)
It felt like it was probably one of the comfiest ways to experience the Amazon. Great staff, knowledgeable guides, all transportation taken care of. Would definitely recommend Inkaterra!

Reviewed on 2026/2/22

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Inkaterra Hacienda Concepcion
See all 56 properties in Madre de Dios Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Madre de Dios Region vacation package cost?
Choose from any combination of hotels, flights and car rentals, and you can be vacationing in Madre de Dios Region from just . And the more you bundle, the more money you save. The getaway of your dreams has never been more affordable.
How do I get a cheap travel package to Madre de Dios Region?
Browse and book everything all in one place with our Madre de Dios Region vacation packages. We have incredible bargains on hotels, flights and more that'll keep your pocket happy and your sense of adventure alive. And, with more than 550 airlines and 1,000,000 properties throughout the world to pick from, you'll have endless opportunities to mix and match as you please.
What are the top hotels in Madre de Dios Region?
For properties in Tambopata with friendly service and cozy beds, you can't beat Kapievi Ecovillage and Inkaterra Reserva Amazonica. If you plan to explore Las Piedras as well, you'll get a solid night's sleep at Copasu Hotel or Tarantula Hostel.
How far in advance should I book my Madre de Dios Region vacation?
Reward yourself with the biggest variety and the lowest prices by booking your vacation to Madre de Dios Region nice and early. Airlines generally advertise flight tickets around 12 months prior to departure, so reserve your spot ASAP. Having said that, Expedia is constantly working to give you the best deals around, so it's never a bad time to book your dream vacation!
What does an Expedia Madre de Dios Region travel package include?
Hotels, flights and car rentals — we connect you to the very best bargains. All you have to do is decide on your favorite combination. After you've made your booking, you can add on the fun stuff like sightseeing activities. Our travel packages make it easy to create an awesome Madre de Dios Region getaway.
What should I know before booking a Madre de Dios Region travel package?
When you book your flights, hotels and car rentals together, you'll enjoy amazing discounts. Whether you're planning a mountain getaway in a cabin or want to stay in a cozy apartment in the city, Expedia will help make it happen.
Can I choose my airline with a Madre de Dios Region Expedia vacation package?
Yes — and it's easy too. Expedia has access to more than 550 partner airlines globally. Our packages give you the flexibility to pick from available flights, hotels and activities that suit you.
If I'm not able to travel, can I cancel my Madre de Dios Region vacation package?
It's difficult to predict what tomorrow might bring, so it's comforting to know that you can cancel or change your Madre de Dios Region vacation package. If you booked in the last 24 hours, you may be entitled to a refund. If your booking is older, your airline, hotel or car rental company may charge a fee. Check our Customer Service Portal to find out more.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.