South Central Houston, TX
Houston
Visit South Central Houston
Popular places to visit
MD Anderson Cancer Center
Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Rice University
Enjoy the collegiate vibe around Rice University, a top university in Houston. Experience the area's acclaimed art scene and great live music.
Houston Zoo
Feed a giraffe, catch a 4-D movie or cool off in the water park at this extraordinary zoo.
University of Houston
Enjoy the collegiate vibe when you visit University of Houston, during your travels in Houston. Experience the acclaimed theater scene and lively festivals in this vibrant area.
Children's Museum of Houston
You can take time to visit Children's Museum of Houston during your travels to Houston. Experience the area's entertainment choices and acclaimed theater scene.
Houston Methodist Hospital
Though Houston Methodist Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
South Central Houston Hotel Deals
Hilton Houston Plaza/Medical Center
Good stay for price and location. The room was fairly clean except shower, which was an easy fix. AC worked well and was turned on for check in. The staff were excellent.
Reviewed on 2026/4/25
Hotel Zaza Houston Museum District
Very cool redesign of the old Warwick Hotel. Room was very nice with great bedding. Staff was friendly and helpful. Really enjoyed the stay
Reviewed on 2026/4/27
InterContinental Houston by IHG
Excellent Hotel! Great price and beautiful and clean , 5 star hotel
Reviewed on 2026/4/26
The Westin Houston Medical Center/Museum District
Absolutely zero effort of keeping their pool clean. Carpet stained in the hallways. Boogers on wall of elevator.
Reviewed on 2026/4/27
Sentral Forme Houston
The check in was awesome. We got there a little early and were able to find the front easily due to the addition info provided. It made finding everything super simple. We were greeted by David and Tiffany. They were so sweet and helpful. Tiffany definitely went above and beyond helping us and showing ...
Reviewed on 2026/4/26
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Nice place
Reviewed on 2026/4/23
Check South Central Houston hotel availability
Other neighborhoods around South Central Houston
Greater Third Ward
While you're in Greater Third Ward, take in top sights like Barbara Jordan & Mickey Leland Archives or Fertitta Center, and hop on the metro to see more the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
Midtown
Characterized by a vibrant nightlife and young residents, this central Houston neighborhood boasts Ensemble Theatre, the largest African-American theater company in the US, and various parks like Midtown Park and Elizabeth Baldwin Park. Easily accessible via METRORail Red Line.
East Downtown Houston
Get to know East Downtown Houston and its many features like its restaurants and live music. You might want to explore sights like Shell Energy Stadium and Giant Beatles Statues, and you can jump on the metro at Leeland/Third Ward Station or EaDo/Stadium Station to get around the city.
Museum District
Known for its ample dining options and fascinating museums, there's plenty to explore in Museum District. You can visit top attractions like Children's Museum of Houston and Houston Natural Science Museum, and jump on the metro at Museum District Station or Hermann Park/Rice U Station to see more of the city.
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.
Downtown Houston
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
