South Central Houston, TX

Houston

A water feature with multiple tiers and a circular viewing platform at the top.
A city skyline at night with illuminated skyscrapers and a large brick plaza in the foreground.
A train on tracks with graffiti on a nearby building.
A park with a gazebo, a fountain, and tall buildings in the background.
A water feature with a cascading waterfall, a grassy hill, and a tall building in the background.

Stay near popular South Central Houston attractions

A large historic building with a red roof and arched windows, surrounded by a well-maintained garden and a clear blue sky.

Rice University

8.6/10 (1,772 reviews)
Enjoy the collegiate vibe around Rice University, a top university in Houston. Experience the area's acclaimed theater scene and fascinating museums.
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South Central Houston Hotel Deals

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
The price is NT$8,327 per night from Oct 18 to Oct 19
NT$8,327
NT$11,000 total
Oct 18 - Oct 19
includes taxes & fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,000 reviews)
"Staff was great! Love the Za Za!"

Reviewed on 2026/9/13

Hotel Zaza Houston Museum District
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
The price is NT$3,364 per night from Oct 18 to Oct 19
NT$3,364
NT$3,973 total
Oct 18 - Oct 19
includes taxes & fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our ...
8.4/10 Very Good! (2,148 reviews)
"I really like the hotel very clean only thing about it no microwave in a charge for parking in breakfast it's not worth the price"

Reviewed on 2026/9/16

Hilton Houston Plaza/Medical Center
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
The price is NT$4,599 per night from Sep 18 to Sep 19
NT$4,599
NT$5,724 total
Sep 18 - Sep 19
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
The Westin Houston Medical Center/Museum District
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
The price is NT$5,291 per night from Sep 19 to Sep 20
NT$5,291
NT$6,827 total
Sep 19 - Sep 20
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
9.4/10 Exceptional! (1,008 reviews)
"Good"

Reviewed on 2026/9/16

InterContinental Houston by IHG
Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District

4 out of 5
6580 Fannin Street Houston TX
The price is NT$5,421 per night from Sep 25 to Sep 26
NT$5,421
NT$7,374 total
Sep 25 - Sep 26
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), a free area shuttle, and room service. Our guests praise the helpful staff ...
Houston Marriott Medical Center/Museum District
Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2.5 out of 5
1301 Braeswood Blvd Houston TX
The price is NT$2,461 per night from Oct 18 to Oct 19
NT$2,461
NT$2,889 total
Oct 18 - Oct 19
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6/10 (1,010 reviews)
"Tyuiio"

Reviewed on 2026/9/16

Extended Stay America Suites Houston Med Ctr Braeswood Bl
See all 1,270 properties in South Central Houston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South Central Houston

Find the best South Central Houston areas and neighborhoods for the activities you enjoy most.
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Downtown Houston

Known for its abundant dining options and live music, there's plenty to explore in Downtown Houston. Top attractions like Daikin Park and Toyota Center are major draws, and you can catch the metro at Central Station Main or Main Street Square Station to see more of the city.

A person walking in front of a building with a brick facade and three arched windows.

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Gerald D. Hines Waterwall Park.

A cityscape with tall buildings, including a prominent one with 'Texas Children's Hospital' on it, under a partly cloudy sky.

Texas Medical Center

Well-liked for its restaurants, museums, and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo is a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

An art gallery with a minimalist design, featuring a central bench and large abstract paintings on the walls.

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

A large rectangular reflecting pool with a tall building in the background.
Photo by George Zimzores
Open Photo by George Zimzores

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.

South Central Houston, TX