Find Resorts & Hotels with Spas in Grand Isle, FL

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Check availability on Grand Isle Resorts & Hotels with Spas

Top Grand Isle Resorts & Hotels with Spas

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Recommended hotels in Grand Isle

Exterior
The Port Inn and Cottages, an Ascend Collection Hotel
The Port Inn and Cottages, an Ascend Collection Hotel
3.5 star property
9.0 out of 10, Wonderful, (390)
"The best weekend! Every staff member was so kind and helpful, we loved having fresh coffee in the lounge, and the breakfast was delicious."
United States
Elizabeth
The price is NT$3,624
NT$4,059 total
includes taxes & fees
Nov 9 - Nov 10
The Port Inn and Cottages, an Ascend Collection Hotel
Free buffet breakfast
Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG
Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG
2.5 star property
8.4 out of 10, Very Good, (437)
"Hotel was in the area we needed to be. Walkable to our location. Variety of restaurants around the area. "
United States
Amy
The price is NT$3,037
NT$3,282 total
includes taxes & fees
Nov 7 - Nov 8
Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG
Suite, Multiple Beds, Accessible, Non Smoking | Desk, iron/ironing board, free WiFi, bed sheets
MainStay Suites Port Saint Joe South
MainStay Suites Port Saint Joe South
2.5 star property
8.6 out of 10, Excellent, (678)
"The hotel is a little older but it was clean and the rooms were a nice size."
United States
Carrie
The price is NT$3,363
NT$3,767 total
includes taxes & fees
Nov 2 - Nov 3
MainStay Suites Port Saint Joe South
Aerial view
Cape Cottages by Panhandle Getaways
Cape Cottages by Panhandle Getaways
3.5 star property
10.0 out of 10, Exceptional, (3)
"Brand new, quaint spot with really comfortable beds. "
United States
Anonymous traveler
The price is NT$5,613
NT$17,968 total
includes taxes & fees
Oct 19 - Oct 20
Cape Cottages by Panhandle Getaways
Lobby
Comfort Suites
Comfort Suites
2.5 star property
8.6 out of 10, Excellent, (700)
"Convenient location & comfortable rooms . "
United States
Heidi
The price is NT$2,856
NT$3,087 total
includes taxes & fees
Oct 30 - Oct 31
Comfort Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Grand Isle Hotel Reviews

Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

10/10 Excellent
"Hotel was in the area we needed to be. Walkable to our location. Variety of restaurants around the area. "
Amy 1-night trip
Posted 4 days ago
Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG
Comfort Suites

Comfort Suites

10/10 Excellent
"Staff was friendly and helpful. Carpets could stand a cleaning, rooms were comfortable and the most part very clean, just need to do a little look see to repair a few flaws. Bed was very comfortable, plenty of comfortable pillows and plenty of towels . When we’re in the area again, we will for sure stay here…"
Karen 3-night trip
Posted 13 days ago
Comfort Suites

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Frequently asked questions

Looking to vacation at a spa hotel in Grand Isle?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Spa hotels are the perfect way to take a break from your daily routine and add a layer of luxury to your vacation.
What's there to see and do in Grand Isle?
Enjoy all that Grand Isle has to offer and visit Mexico Beach, Saint Joe Beach, and Windmark Beach. If you have extra time while you're in the area, you might want to see Forgotten Coast Sea Turtle Center and St. Joseph Peninsula State Park.
What is a Grand Isle spa hotel?
Spa hotels in Grand Isle provide lodging and have an on-site spa offering services such as therapies as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.