Find hotels in East Main Street, Grand Junction

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for East Main Street hotels

Dtwn Walkability! Grand Junction Couple's Retreat

Dtwn Walkability! Grand Junction Couple's Retreat
3.0 star property
East Main Street
10.0 out of 10, Exceptional, (3 reviews)
"Our stay was fantastic! The location was perfect—close to everything. The property was clean and loved the decor. The host was super responsive and helpful, making our trip stress-free. Highly recommend!"
United States
renee
The price is NT$3,573
NT$7,944 total
includes taxes & fees
Jan 31 - Feb 1
Dtwn Walkability! Grand Junction Couple's Retreat

La Quinta Inn & Suites by Wyndham Grand Junction

La Quinta Inn & Suites by Wyndham Grand Junction
3.0 star property
Horizon Drive District, 5.4 km from East Main Street
8.8 out of 10, Excellent, (2,805 reviews)
"This was a great place to stay, and breakfast was also as expected"
United States
Michael
The price is NT$2,172
NT$2,491 total
includes taxes & fees
Feb 8 - Feb 9
La Quinta Inn & Suites by Wyndham Grand Junction

Best Western Grande River Inn & Suites

Best Western Grande River Inn & Suites
2.5 star property
8.7 km from East Main Street
8.8 out of 10, Excellent, (806 reviews)
"Very nice place."
United States
Harold
The price is NT$2,638
NT$2,803 total
includes taxes & fees
Feb 5 - Feb 6
Best Western Grande River Inn & Suites

Ramada by Wyndham Grand Junction

Ramada by Wyndham Grand Junction
2.5 star property
Horizon Drive District, 5.3 km from East Main Street
8.4 out of 10, Very Good, (1,883 reviews)
"Easy to find, close to dining, clean and hospitable staff."
United States
Darrell
The price is NT$1,835
NT$2,104 total
includes taxes & fees
Mar 2 - Mar 3
Ramada by Wyndham Grand Junction

Wine Country Inn Palisade

Wine Country Inn Palisade
3.5 star property
17.1 km from East Main Street
9.6 out of 10, Exceptional, (1,000 reviews)
"Beautiful property, great breakfast!"
United States
Amy
Wine Country Inn Palisade

Grand Vista Hotel

Grand Vista Hotel
3.5 star property
Horizon Drive District, 5.5 km from East Main Street
8.2 out of 10, Very Good, (3,499 reviews)
"Very clean and great location!"
United States
Heath Maurice
Grand Vista Hotel

Econo Lodge Grand Junction North

Econo Lodge Grand Junction North
2.0 star property
Horizon Drive District, 5.2 km from East Main Street
8.4 out of 10, Very Good, (1,000 reviews)
"Hotel was easy to find and worked quite well for a good night sleep after driving 13 hours. "
United States
Peter
The price is NT$2,101
NT$2,409 total
includes taxes & fees
Feb 8 - Feb 9
Econo Lodge Grand Junction North

Clarion Inn Grand Junction

Clarion Inn Grand Junction
2.5 star property
Horizon Drive District, 5.3 km from East Main Street
8.4 out of 10, Very Good, (1,712 reviews)
"Breakfast was good and gym , pool are in good condition. Family friendly hotel "
United States
kranthikar
The price is NT$2,252
NT$2,583 total
includes taxes & fees
Feb 9 - Feb 10
Clarion Inn Grand Junction

Tru by Hilton Grand Junction Downtown

Tru by Hilton Grand Junction Downtown
2.5 star property
Historic Grand Junction, 1.4 km from East Main Street
9.2 out of 10, Wonderful, (1,000 reviews)
"Clean rooms, quiet, friendly staff! Close to some of the best restaurants in grand junction!"
United States
Emily
The price is NT$2,678
NT$3,071 total
includes taxes & fees
Feb 8 - Feb 9
Tru by Hilton Grand Junction Downtown

Comfort Inn & Suites Fruita - Grand Junction

Comfort Inn & Suites Fruita - Grand Junction
2.5 star property
18.5 km from East Main Street
8.4 out of 10, Very Good, (1,000 reviews)
"Check-in was great and room was perfect. "
United States
Edward
The price is NT$1,762
NT$2,014 total
includes taxes & fees
Feb 8 - Feb 9
Comfort Inn & Suites Fruita - Grand Junction

Doubletree Hotel Grand Junction

Doubletree Hotel Grand Junction
4.0 star property
Horizon Drive District, 5 km from East Main Street
8.2 out of 10, Very Good, (1,001 reviews)
"Room was clean staff was very nice "
United States
Erick
The price is NT$3,021
NT$3,463 total
includes taxes & fees
Mar 1 - Mar 2
Doubletree Hotel Grand Junction

La Quinta Inn & Suites by Wyndham Fruita

La Quinta Inn & Suites by Wyndham Fruita
3.0 star property
18.8 km from East Main Street
8.4 out of 10, Very Good, (1,002 reviews)
"Breakfast was nice. "
United States
Jeremy
The price is NT$2,054
NT$2,347 total
includes taxes & fees
Feb 1 - Feb 2
La Quinta Inn & Suites by Wyndham Fruita

Hotel Maverick

Hotel Maverick
4.0 star property
Capitol Hill, 1.6 km from East Main Street
9.6 out of 10, Exceptional, (1,001 reviews)
"Great location for an athletic event at CMU! The coffee shop and restaurant are both amazing!! Our room was so comfy and nice, and the staff was super sweet. Looking forward to staying here again on our next trip into Grand Junction! "
United States
Alison
Hotel Maverick

Camp Eddy

Camp Eddy
1.0 star property
Pear Park, 1.5 km from East Main Street
9.4 out of 10, Exceptional, (300 reviews)
"Room was adorable stayed in number 2 tiny home. Great river view and was very clean. "
Canada
Victoria
The price is NT$2,229
NT$4,235 total
includes taxes & fees
Feb 2 - Feb 3
Camp Eddy

Super 8 by Wyndham Fruita

Super 8 by Wyndham Fruita
2.0 star property
18.6 km from East Main Street
8.4 out of 10, Very Good, (1,001 reviews)
"The place was great. "
United States
Craig
The price is NT$1,834
NT$2,096 total
includes taxes & fees
Feb 1 - Feb 2
Super 8 by Wyndham Fruita

Courtyard by Marriott Grand Junction

Courtyard by Marriott Grand Junction
3.0 star property
Horizon Drive District, 5.6 km from East Main Street
8.4 out of 10, Very Good, (1,000 reviews)
"Nice staff and ER stay when my flight was delayed overnight. The breakfast options were great too."
United States
Rachel
The price is NT$3,103
NT$3,558 total
includes taxes & fees
Feb 3 - Feb 4
Courtyard by Marriott Grand Junction

Hampton Inn Grand Junction Downtown/Historic Main Street

Hampton Inn Grand Junction Downtown/Historic Main Street
2.5 star property
Historic Grand Junction, 1.5 km from East Main Street
8.8 out of 10, Excellent, (1,000 reviews)
"Friendly staff, clean room, great location."
United States
Katherine
The price is NT$2,855
NT$3,273 total
includes taxes & fees
Feb 1 - Feb 2
Hampton Inn Grand Junction Downtown/Historic Main Street

Home2 Suites by Hilton Grand Junction Northwest

Home2 Suites by Hilton Grand Junction Northwest
3.0 star property
24 Road Corridor, 5.8 km from East Main Street
9.2 out of 10, Wonderful, (892 reviews)
"Friendly staff, great breakfast."
United States
Larry
The price is NT$4,008
NT$4,596 total
includes taxes & fees
Feb 1 - Feb 2
Home2 Suites by Hilton Grand Junction Northwest

Motel 6 Grand Junction, CO

Motel 6 Grand Junction, CO
2.0 star property
Horizon Drive District, 5.8 km from East Main Street
6.0 out of 10, (1,004 reviews)
"Great Staff!!"
United States
Kantoa
The price is NT$1,755
NT$2,013 total
includes taxes & fees
Jan 31 - Feb 1
Motel 6 Grand Junction, CO

Comfort Inn Grand Junction I-70

Comfort Inn Grand Junction I-70
2.5 star property
Horizon Drive District, 5.4 km from East Main Street
8.6 out of 10, Excellent, (1,002 reviews)
"Clean rooms, great staff and good location "
United States
John
The price is NT$2,507
NT$2,875 total
includes taxes & fees
Feb 8 - Feb 9
Comfort Inn Grand Junction I-70
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in East Main Street

Find the best East Main Street areas and neighborhoods for the activities you enjoy most.

Redlands

You'll enjoy the mountain views and wineries in Redlands. You might want to make time for a stop at Colorado National Monument or Redlands Mesa Golf Club.

Downtown

While there might not be top attractions in Downtown, you can explore the larger area and discover places like Western Colorado Botanical Gardens and Bananas Fun Park.

Pear Park

If you're spending some time in Pear Park, Colorado River and James M. Robb – Colorado River State Park are top sights worth seeing.

Historic Grand Junction

Historic Grand Junction is popular for its abundant dining options, and you can check out Museum of the West, a top attraction in the neighborhood.

Orchard Mesa

If you're spending some time in Orchard Mesa, Mesa County Fairgrounds and Gunnison River are top sights worth seeing.

Top East Main Street Hotel Reviews

Frequently asked questions

What's it like in East Main Street?
Travelers will be sure to enjoy their time in Grand Junction's East Main Street neighborhood.
How many hotels will I be able to find in the East Main Street area?
If you're searching for places to stay in Grand Junction, Expedia has something to meet your needs with 22 East Main Street hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in East Main Street, will I receive a refund?
Yes, the majority of hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to get top deals in East Main Street.
Where can I learn more about changing or cancelling my trip to East Main Street?
To find more details about updating your trip to East Main Street or cancelling it, go to https://www.expedia.com/service/.
What is there to do around this Grand Junction neighborhood?
A few places to visit in the area around East Main Street include Museum of the West, Western Colorado Botanical Gardens, and Elliott Tennis Center. While you're out sightseeing, Western Colorado Center for the Arts and Tennis Junction Indoor Center are a couple of additional sights to visit in Grand Junction.

Explore a world of travel with Expedia