Find Family Hotels in Charleston, MO
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Charleston Family Hotels
Top Charleston Family Hotels

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
9.4 out of 10, Exceptional, (1006)
The price is NT$2,751
NT$3,163 total
includes taxes & fees
Sep 7 - Sep 8

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
9.6 out of 10, Exceptional, (1018)
The price is NT$2,751
NT$3,103 total
includes taxes & fees
Sep 4 - Sep 5

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
9.0 out of 10, Wonderful, (1005)
The price is NT$2,140
NT$2,414 total
includes taxes & fees
Sep 1 - Sep 2

Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MO
6.6 out of 10, (585)
The price is NT$1,767
NT$1,961 total
includes taxes & fees
Sep 8 - Sep 9

Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
9.4 out of 10, Exceptional, (1007)
The price is NT$2,354
NT$2,706 total
includes taxes & fees
Sep 15 - Sep 16

Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
9.0 out of 10, Wonderful, (1005)
The price is NT$2,140
NT$2,414 total
includes taxes & fees
Sep 1 - Sep 2

Quality Inn Cairo I-57
Quality Inn Cairo I-57
6.6 out of 10, (265)
The price is NT$2,084
NT$2,313 total
includes taxes & fees
Oct 1 - Oct 2
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Charleston Hotel Reviews
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Find More Hotels near Charleston
More Hotel Options in Charleston
- Business Hotels in Charleston
- Cheap Hotels in Charleston
- Hotels with Bars in Charleston
- Hotels with Free Parking in Charleston
- Hotels with WiFi in Charleston
- Hotels with a Pool in Charleston
- Hotels with smoking rooms in Charleston
- Pet-friendly Hotels in Charleston
- Resorts & Hotels with Spas in Charleston
More Accommodation Types in Charleston
- Condo Rentals in Missouri
- Apartments in Missouri
- Cottages in Missouri
- Vacation Homes in Missouri
- Motels in Missouri
- Cabin Rentals in Missouri
- B&B in Missouri
- Aparthotels in Missouri
- Guest Houses in Missouri
- Lodges in Missouri
- Resorts in Missouri
- Villas in Missouri
- Inns in Missouri
- RV Parks in Missouri
- Condo Resorts in Missouri
- Hostels in Missouri
- Chalets in Missouri
- Residences in Missouri
Hotels near popular Charleston Attractions
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Ohio River
- Hotels near Southeast Missouri State University
- Hotels near Reelfoot Lake
- Hotels near Isle Casino Cape Girardeau
- Hotels near Riverfront Bridge Park
- Hotels near Columbus-Belmont State Park
- Hotels near Riverfront Park
- Hotels near Cape Rock Park
Charleston Hotels by Star Rating
Explore more hotels
- Candlewood Suites Cape Girardeau by IHG
- Courtyard by Marriott Cape Girardeau Downtown
- Drury Inn & Suites Cape Girardeau
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
- Days Inn and Suites by Wyndham Sikeston
- Hampton Inn Sikeston
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Hampton Inn Cape Girardeau I 55 East
- Fairfield Inn & Suites by Marriott Sikeston
- Super 8 by Wyndham Sikeston/Miner Area
- Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
- Holiday Inn Express & Suites Sikeston Southwest by IHG
- Country Yard Inn and Suite
- Town House Inn Cape Giradreau
- Comfort Inn & Suites Sikeston I-55
- Quality Inn Cairo I-57
- TownePlace Suites by Marriott Sikeston
- La Center Motel
- Rockwood Inn
More ways to book
Expedia's Latest Trends
Hotels
Packages
General
- Visit Fort Myers Beach
- Visit Destin
- Visit Springfield
- Visit Portland
- Visit Santa Cruz
- Visit Napa
- Visit Bainbridge Island
- Visit Cupertino
- Visit Palm Springs
- Visit Yellowstone National Park
- Visit Sequoia National Park
- Visit Mount Shasta
- Visit Hawk Point
- Visit South Lake Tahoe
- Visit San Diego
- Visit Newport Beach
- Visit Honolulu
- Visit Naples
- Visit San Jose
- Visit Helen