Find Family Hotels in Charleston, MO

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Check availability on Charleston Family Hotels

Our top choices for Charleston family-friendly hotels

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (409 reviews)
  • cleanliness
    Kids stay active and happy with free activities, family-friendly rooms, and morning meals at this welcoming Charleston hotel.
The price is NT$2,229
NT$2,474 total
includes taxes & fees
Mar 20 - Mar 21
The Riverstone Hotel Charleston-Sikeston

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (625 reviews)
  • cleanliness
    Unleash family fun in Charleston with premium TV channels, pay movies, and free cribs, all while friendly staff elevate your stay.
The price is NT$1,978
NT$2,195 total
includes taxes & fees
Mar 20 - Mar 21
Super 8 by Wyndham Charleston/Sikeston East MO

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,003 reviews)
  • cleanliness
    Children's paradise awaits with splash-worthy indoor and outdoor pools, free breakfast buffet, and family-focused amenities all day long.
The price is NT$2,993
NT$3,442 total
includes taxes & fees
Mar 26 - Mar 27
Drury Inn & Suites Sikeston, MO

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,001 reviews)
  • cleanliness
    A family paradise with splash-worthy fun awaits, where complimentary breakfast and an indoor pool create lasting memories for all ages.
The price is NT$3,184
NT$3,592 total
includes taxes & fees
Mar 23 - Mar 24
Drury Plaza Hotel Cape Girardeau Conference Center

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Family-friendly adventures await with free breakfast, cribs, and easy access to Cape Splash Aquatic Center, just minutes away.
The price is NT$2,293
NT$2,586 total
includes taxes & fees
Mar 29 - Mar 30
Pear Tree Inn Cape Girardeau West

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (166 reviews)
The price is NT$2,951
NT$3,329 total
includes taxes & fees
Mar 29 - Mar 30
Fairfield Inn & Suites by Marriott Cape Girardeau

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.6 out of 10, (282 reviews)
  • cleanliness
    Quiet family comfort with free breakfast and modern amenities along the Mississippi River makes this hotel perfect for stress-free trips.
The price is NT$2,288
NT$2,540 total
includes taxes & fees
Mar 29 - Mar 30
Quality Inn Cairo I-57

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.2 out of 10, Very Good, (905 reviews)
  • cleanliness
    Family-friendly hotel offers indoor pool, fitness center, and free laundry near Cape Splash Aquatic Center.
The price is NT$2,420
NT$2,906 total
includes taxes & fees
Mar 23 - Mar 24
Candlewood Suites Cape Girardeau by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at family-friendly hotels in Charleston

Top Charleston Hotel Reviews

Frequently asked questions

What's Charleston like for family-friendly vacations?
The destination of Charleston is a good option if you've been considering a getaway with the kids. The entertainment, theaters, and restaurants are just a few things that make this an attractive family vacation spot. Arrange a flight into Cairo, IL (CIR-Cairo Regional), which is located 11.8 mi (19 km) from the city center.
When's the best time to book a family-friendly vacation in Charleston?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Charleston is 59 inches.
What's there to see and do with your family in Charleston?
While you and the family are vacationing in Charleston, you might want to check out some of the attractions here such as Front Street Studio & Art Gallery, Mississippi River, and Ohio River. Make sure you have lots of time for activities like Shawnee National Forest and Ohio River Valley.

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