Find Family Hotels in Charleston, MO

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Charleston Family Hotels

Tonight
Dec 1 - Dec 2
Tomorrow
Dec 2 - Dec 3
This weekend
Dec 5 - Dec 7
Next weekend
Dec 12 - Dec 14

Top Charleston Family Hotels

Front of property - evening/night
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
Charleston
6.6 out of 10, (611)
"Staff was great! Room was nice. "
United States
Lana
The price is NT$1,841
NT$2,043 total
includes taxes & fees
Dec 2 - Dec 3
Super 8 by Wyndham Charleston/Sikeston East MO
Desk, laptop workspace, blackout drapes, iron/ironing board
Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston

2.5 star property
Charleston
6.8 out of 10, (406)
"The staff was very friendly and accommodating "
United States
Arturo
The price is NT$2,062
NT$2,289 total
includes taxes & fees
Dec 8 - Dec 9
Quality Inn Charleston - Sikeston
Property amenity
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1010)
"Clean room, great location and friendly staff"
United States
Mark
The price is NT$2,825
NT$3,248 total
includes taxes & fees
Dec 6 - Dec 7
Drury Inn & Suites Sikeston, MO
Lobby
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1007)
"I liked how comfortable the beds and pillows were."
United States
Christine
The price is NT$2,197
NT$2,479 total
includes taxes & fees
Dec 7 - Dec 8
Pear Tree Inn Cape Girardeau Near the Medical Center
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1006)
"Very nice stay."
United States
Charity
The price is NT$2,825
NT$3,187 total
includes taxes & fees
Dec 11 - Dec 12
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1006)
"Everything was clean, staff was friendly "
United States
Matthew
The price is NT$2,417
NT$2,778 total
includes taxes & fees
Dec 6 - Dec 7
Pear Tree Inn Sikeston
Lobby
Quality Inn Cairo I-57

Quality Inn Cairo I-57

2.5 star property
Cairo
6.6 out of 10, (272)
"Break fast was excellent "
United States
Uma
The price is NT$2,267
NT$2,516 total
includes taxes & fees
Dec 12 - Dec 13
Quality Inn Cairo I-57
Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (137)
"Great hotel!"
United States
Will
The price is NT$2,762
NT$3,116 total
includes taxes & fees
Dec 11 - Dec 12
Fairfield Inn & Suites by Marriott Cape Girardeau
Property amenity
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 star property
Cape Girardeau
8.0 out of 10, Very Good, (875)
"Great room"
United States
Kevin
The price is NT$2,210
NT$2,666 total
includes taxes & fees
Dec 7 - Dec 8
Candlewood Suites Cape Girardeau by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Charleston Hotel Reviews

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

10/10 Excellent
"I liked how comfortable the beds and pillows were."
Christine 4-night trip
Posted 1 day ago
Pear Tree Inn Cape Girardeau Near the Medical Center

Explore a world of travel with Expedia

Frequently asked questions

What's Charleston like for family-friendly vacations?
The destination of Charleston is a good option if you've been considering a getaway with the kids. The entertainment, theaters, and restaurants are just a few things that make this an attractive family vacation spot. Arrange a flight into Cairo, IL (CIR-Cairo Regional), which is located 11.8 mi (19 km) from the city center.
When's the best time to book a family-friendly vacation in Charleston?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Charleston is 59 inches.
What's there to see and do with your family in Charleston?
While you and the family are vacationing in Charleston, you might want to check out some of the attractions here such as Front Street Studio & Art Gallery, Mississippi River, and Ohio River. Make sure you have lots of time for activities like Shawnee National Forest and Ohio River Valley.